Shyam Sundar Krishnakumar PhD

Research Scientist in Cell Biology

Departments & Organizations

Cell Biology: Rothman Lab


Research Interests

Synaptic Transmission, Synaptic Regulation, SNAREs, Complexin, Synaptotagmin  more...


Education

  • M.Sc., Indian Inst Of Tech, 2001
  • Ph.D., Stony Brook University, 2007

Selected Publications

  • Krishnakumar SS, Kümmel D, Jones SJ, Radoff DT, Reinisch KM and Rothman JE. Conformational Dynamics of Calcium-triggered Activation of Fusion by Synaptotagmin. Biophys J. (2013) 105: 2507-16
  • Krishnakumar SS, Radoff DT, Kümmel D, , Giraudo CG, Li F, Khandan L, Baguley SW, Coleman J, Reinisch KM, Pincet F and Rothman JE A Conformational Switch in Complexin is Required for Synaptotagmin to Trigger Synaptic Fusion. Nat Struct Mol Biol (2011) 18: 934-40
  • Kümmel D, Krishnakumar SS, Radoff DT, Li F, Giraudo CG, Pincet F, Rothman JE and Reinisch KM Complexin Cross-links Pre-fusion SNAREs into a Zig-Zag Array. Nat Struct Mol Biol (2011) 18: 927-33.

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