Publications

Bolen CR, Ding S, Robek MD and Kleinstein SH: Dynamic expression profiling of type I and type III interferon-stimulated hepatocytes reveals a stable hierarchy of gene expression. Hepatology. 2014 Apr;59 (4) :1262-72. Epub 2014 Feb 18. PMID: 23929627


van den Pol AN, Ding S and Robek MD: Long-distance interferon signaling within the brain blocks virus spread. J Virol. 2014 Apr;88 (7) :3695-704. Epub 2014 Jan 15. PMID: 24429359


Ding S, Khoury-Hanold W, Iwasaki A and Robek MD: Epigenetic reprogramming of the type III interferon response potentiates antiviral activity and suppresses tumor growth. PLoS Biol. 2014 Jan;12 (1) :e1001758. Epub 2014 Jan 7. PMID: 24409098

Cobleigh MA, Wei X and Robek MD: A vesicular stomatitis virus-based therapeutic vaccine generates a functional CD8 T cell response to hepatitis B virus in transgenic mice. J Virol. 2013 Mar;87 (5) :2969-73. Epub 2012 Dec 26. PMID: 23269785


Cobleigh MA and Robek MD: Protective and pathological properties of IL-22 in liver disease: implications for viral hepatitis. Am J Pathol. 2013 Jan;182 (1) :21-8. Epub 2012 Nov 14. PMID: 23159948


Bolen CR, Robek MD, Brodsky L, Schulz V, Lim JK, Taylor MW and Kleinstein SH: The blood transcriptional signature of chronic hepatitis C virus is consistent with an ongoing interferon-mediated antiviral response. J Interferon Cytokine Res. 2013 Jan;33 (1) :15-23. Epub 2012 Oct 15. PMID: 23067362


Garcia ML, Reynolds TD, Mothes W and Robek MD: Functional characterization of the putative hepatitis B virus core protein late domain using retrovirus chimeras. PLoS One. 2013;8 (8) :e72845. Epub 2013 Aug 29. PMID: 24009707

Cobleigh MA, Bradfield C, Liu Y, Mehta A and Robek MD: The immune response to a vesicular stomatitis virus vaccine vector is independent of particulate antigen secretion and protein turnover rate. J Virol. 2012 Apr;86 (8) :4253-61. Epub 2012 Feb 15. PMID: 22345454

Zhang Y, Cobleigh MA, Lian JQ, Huang CX, Booth CJ, Bai XF and Robek MD: A proinflammatory role for interleukin-22 in the immune response to hepatitis B virus. Gastroenterology. 2011 Nov;141 (5) :1897-906. Epub 2011 Jun 25. PMID: 21708106

Pagliaccetti NE and Robek MD: Interferon-lambda in the immune response to hepatitis B virus and hepatitis C virus. J Interferon Cytokine Res. 2010 Aug;30 (8) :585-90. PMID: 20645875


Cobleigh MA, Buonocore L, Uprichard SL, Rose JK and Robek MD: A vesicular stomatitis virus-based hepatitis B virus vaccine vector provides protection against challenge in a single dose. J Virol. 2010 Aug;84 (15) :7513-22. Epub 2010 May 26. PMID: 20504927


Pagliaccetti NE and Robek MD: Interferon-λ in HCV Infection and Therapy. Viruses. 2010 Aug;2 (8) :1589-602. Epub 2010 Aug 5. PMID: 21994696


Pagliaccetti NE, Chu EN, Bolen CR, Kleinstein SH and Robek MD: Lambda and alpha interferons inhibit hepatitis B virus replication through a common molecular mechanism but with different in vivo activities. Virology. 2010 Jun 5;401 (2) :197-206. Epub 2010 Mar 29. PMID: 20303135


Bandi P, Pagliaccetti NE and Robek MD: Inhibition of type III interferon activity by orthopoxvirus immunomodulatory proteins. J Interferon Cytokine Res. 2010 Mar;30 (3) :123-34. PMID: 20038204


Zhang Y, Lian JQ, Huang CX, Wang JP, Wei X, Nan XP, Yu HT, Jiang LL, Wang XQ, Zhuang Y, Li XH, Li Y, Wang PZ, Robek MD and Bai XF: Overexpression of Toll-like receptor 2/4 on monocytes modulates the activities of CD4(+)CD25(+) regulatory T cells in chronic hepatitis B virus infection. Virology. 2010 Feb 5;397 (1) :34-42. Epub 2009 Nov 27. PMID: 19945134


Bandi P, Garcia ML, Booth CJ, Chisari FV and Robek MD: Bortezomib inhibits hepatitis B virus replication in transgenic mice. Antimicrob Agents Chemother. 2010 Feb;54 (2) :749-56. Epub 2009 Nov 30. PMID: 19949053

Garcia ML, Byfield R and Robek MD: Hepatitis B virus replication and release are independent of core lysine ubiquitination. J Virol. 2009 May;83 (10) :4923-33. Epub 2009 Feb 25. PMID: 19244316

Pagliaccetti NE, Eduardo R, Kleinstein SH, Mu XJ, Bandi P and Robek MD: Interleukin-29 functions cooperatively with interferon to induce antiviral gene expression and inhibit hepatitis C virus replication. J Biol Chem. 2008 Oct 31;283 (44) :30079-89. Epub 2008 Aug 29. PMID: 18757365

Ying C, Li Y, Leung CH, Robek MD and Cheng YC: Unique antiviral mechanism discovered in anti-hepatitis B virus research with a natural product analogue. Proc Natl Acad Sci U S A. 2007 May 15;104 (20) :8526-31. Epub 2007 May 8. PMID: 17488817


Wollmann G, Robek MD and van den Pol AN: Variable deficiencies in the interferon response enhance susceptibility to vesicular stomatitis virus oncolytic actions in glioblastoma cells but not in normal human glial cells. J Virol. 2007 Feb;81 (3) :1479-91. Epub 2006 Nov 15. PMID: 17108037


Robek MD, Garcia ML, Boyd BS and Chisari FV: Role of immunoproteasome catalytic subunits in the immune response to hepatitis B virus. J Virol. 2007 Jan;81 (2) :483-91. Epub 2006 Nov 1. PMID: 17079320


van den Pol AN, Robek MD, Ghosh PK, Ozduman K, Bandi P, Whim MD and Wollmann G: Cytomegalovirus induces interferon-stimulated gene expression and is attenuated by interferon in the developing brain. J Virol. 2007 Jan;81 (1) :332-48. Epub 2006 Oct 25. PMID: 17065212

Ramsburg E, Publicover J, Buonocore L, Poholek A, Robek M, Palin A and Rose JK: A vesicular stomatitis virus recombinant expressing granulocyte-macrophage colony-stimulating factor induces enhanced T-cell responses and is highly attenuated for replication in animals. J Virol. 2005 Dec;79 (24) :15043-53. PMID: 16306575


Isogawa M, Robek MD, Furuichi Y and Chisari FV: Toll-like receptor signaling inhibits hepatitis B virus replication in vivo. J Virol. 2005 Jun;79 (11) :7269-72. PMID: 15890966


Robek MD, Boyd BS and Chisari FV: Lambda interferon inhibits hepatitis B and C virus replication. J Virol. 2005 Mar;79 (6) :3851-4. PMID: 15731279

Robek MD, Boyd BS, Wieland SF and Chisari FV: Signal transduction pathways that inhibit hepatitis B virus replication. Proc Natl Acad Sci U S A. 2004 Feb 10;101 (6) :1743-7. Epub 2004 Feb 2. PMID: 14757813

Robek MD, Wieland SF and Chisari FV: Inhibition of hepatitis B virus replication by interferon requires proteasome activity. J Virol. 2002 Apr;76 (7) :3570-4. PMID: 11884582