Welcome to the Park Lab

Overexpression of four factors (Oct4, Sox2, Klf4, Myc, or Oct4, Sox2, Nanog, Lin28) reprograms somatic cells to become induced pluripotent stem cells (iPSCs). Reprogramming accompanies genetic and epigenetic changes. We will investigate the molecular mechanism of somatic cell reprogramming. iPSCs provide an incredible resource for cell-based therapy, in vitro disease model and screening drugs. We apply the iPSCs to investigate one of the most prevalent female mental retardation disorders called Rett syndrome.

Principal Investigator

In-Hyun Park, PhD

Associate Professor of Genetics and Associate Professor in the Child Study Center

Contact Info
Lab
The Park Lab
Amistad Street Building
10 Amistad Street
New Haven, CT 06519