Selected Publications

Cheung WK, Nguyen DX: Lineage factors and differentiation states in lung cancer progression. Oncogene. 2015 Mar 30; 2015 Mar 30. PMID: 25823023

Arnal-Estapé A, Nguyen DX: Sweets for a bitter end: lung cancer cell-surface protein glycosylation mediates metastatic colonization. Cancer Discov. 2015 Feb. PMID: 25656895

Haskins JW, Nguyen DX, Stern DF: Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration. Sci Signal. 2014 Dec 9; 2014 Dec 9. PMID: 25492965

Karlin KL, Mondal G, Hartman JK, Tyagi S, Kurley SJ, Bland CS, Hsu TY, Renwick A, Fang JE, Migliaccio I, Callaway C, Nair A, Dominguez-Vidana R, Nguyen DX, Osborne CK, Schiff R, Yu-Lee LY, Jung SY, Edwards DP, Hilsenbeck SG, Rosen JM, Zhang XH, Shaw CA, Couch FJ, Westbrook TF: The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor. Cell Rep. 2014 Nov 20; 2014 Nov 6. PMID: 25453754

Colavito SA, Zou MR, Yan Q, Nguyen DX, Stern DF: Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway. Breast Cancer Res. 2014 Sep 25; 2014 Sep 25. PMID: 25252859

Zito G, Saotome I, Liu Z, Ferro EG, Sun TY, Nguyen DX, Bilguvar K, Ko CJ, Greco V: Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk. Nat Commun. 2014 Mar 26; 2014 Mar 26. PMID: 24667544

Cao J, Liu Z, Cheung WK, Zhao M, Chen SY, Chan SW, Booth CJ, Nguyen DX, Yan Q: Histone demethylase RBP2 is critical for breast cancer progression and metastasis. Cell Rep. 2014 Mar 13; 2014 Feb 27. PMID: 24582965

Breindel JL, Haskins JW, Cowell EP, Zhao M, Nguyen DX, Stern DF: EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis. Cancer Res. 2013 Aug 15; 2013 Jun 21. PMID: 23794705

Cheung WK, Zhao M, Liu Z, Stevens LE, Cao PD, Fang JE, Westbrook TF, Nguyen DX: Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis. Cancer Cell. 2013 Jun 10; 2013 May 23. PMID: 23707782

Cao PD, Cheung WK, Nguyen DX: Cell lineage specification in tumor progression and metastasis. Discov Med. 2011 Oct. PMID: 22031670

Sun T, Aceto N, Meerbrey KL, Kessler JD, Zhou C, Migliaccio I, Nguyen DX, Pavlova NN, Botero M, Huang J, Bernardi RJ, Schmitt E, Hu G, Li MZ, Dephoure N, Gygi SP, Rao M, Creighton CJ, Hilsenbeck SG, Shaw CA, Muzny D, Gibbs RA, Wheeler DA, Osborne CK, Schiff R, Bentires-Alj M, Elledge SJ, Westbrook TF: Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase. Cell. 2011 Mar 4. PMID: 21376233

Nguyen DX: Tracing the origins of metastasis. J Pathol. 2011 Jan; 2010 Oct 29. PMID: 21125675

Bos PD, Nguyen DX, Massagué J: Modeling metastasis in the mouse. Curr Opin Pharmacol. 2010 Oct; 2010 Jul 1. PMID: 20598638

Kim MY, Oskarsson T, Acharyya S, Nguyen DX, Zhang XH, Norton L, Massagué J: Tumor self-seeding by circulating cancer cells. Cell. 2009 Dec 24. PMID: 20064377

Nguyen DX, Chiang AC, Zhang XH, Kim JY, Kris MG, Ladanyi M, Gerald WL, Massagué J: WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis. Cell. 2009 Jul 10; 2009 Jul 2. PMID: 19576624

Bos PD, Zhang XH, Nadal C, Shu W, Gomis RR, Nguyen DX, Minn AJ, van de Vijver MJ, Gerald WL, Foekens JA, Massagué J: Genes that mediate breast cancer metastasis to the brain. Nature. 2009 Jun 18; 2009 May 6. PMID: 19421193

Nguyen DX, Bos PD, Massagué J: Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer. 2009 Apr. PMID: 19308067

Nguyen DX, Massagué J: Genetic determinants of cancer metastasis. Nat Rev Genet. 2007 May. PMID: 17440531

Minn AJ, Gupta GP, Padua D, Bos P, Nguyen DX, Nuyten D, Kreike B, Zhang Y, Wang Y, Ishwaran H, Foekens JA, van de Vijver M, Massagué J: Lung metastasis genes couple breast tumor size and metastatic spread. Proc Natl Acad Sci U S A. 2007 Apr 17; 2007 Apr 9. PMID: 17420468

Gupta GP, Nguyen DX, Chiang AC, Bos PD, Kim JY, Nadal C, Gomis RR, Manova-Todorova K, Massagué J: Mediators of vascular remodelling co-opted for sequential steps in lung metastasis. Nature. 2007 Apr 12. PMID: 17429393