Publications

Bai JP, Moeini-Naghani I, Zhong S, Li FY, Bian S, Sigworth FJ, Santos-Sacchi J, Navaratnam D: Current carried by the Slc26 family member prestin does not flow through the transporter pathway. Sci Rep. 2017 Apr 19; 2017 Apr 19. PMID: 28422190

Tan WJT, Song L, Graham M, Schettino A, Navaratnam D, Yarbrough WG, Santos-Sacchi J, Ivanova AV: Novel Role of the Mitochondrial Protein Fus1 in Protection from Premature Hearing Loss via Regulation of Oxidative Stress and Nutrient and Energy Sensing Pathways in the Inner Ear. Antioxid Redox Signal. 2017 Mar 9; 2017 Mar 9. PMID: 28135838

Fleming MR, Brown MR, Kronengold J, Zhang Y, Jenkins DP, Barcia G, Nabbout R, Bausch AE, Ruth P, Lukowski R, Navaratnam DS, Kaczmarek LK: Stimulation of Slack K(+) Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex. Cell Rep. 2016 Aug 30; 2016 Aug 18. PMID: 27545877

Zhang Y, Zhang XF, Fleming MR, Amiri A, El-Hassar L, Surguchev AA, Hyland C, Jenkins DP, Desai R, Brown MR, Gazula VR, Waters MF, Large CH, Horvath TL, Navaratnam D, Vaccarino FM, Forscher P, Kaczmarek LK: Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating. Cell. 2016 Apr 7; 2016 Mar 17. PMID: 26997484

Moeini-Naghani I, Navaratnam DS: Yeast Two-Hybrid Screening to Test for Protein-Protein Interactions in the Auditory System. Methods Mol Biol. 2016. PMID: 27259923

Zhang Y, Moeini-Naghani I, Bai J, Santos-Sacchi J, Navaratnam DS: Tyrosine motifs are required for prestin basolateral membrane targeting. Biol Open. 2015 Jan 16; 2015 Jan 16. PMID: 25596279

Surguchev A, Bai JP, Joshi P, Navaratnam D: Hair cell BK channels interact with RACK1, and PKC increases its expression on the cell surface by indirect phosphorylation. Am J Physiol Cell Physiol. 2012 Jul 15; 2012 Apr 25. PMID: 22538239

Bai JP, Surguchev A, Joshi P, Gross L, Navaratnam D: CDK5 interacts with Slo and affects its surface expression and kinetics through direct phosphorylation. Am J Physiol Cell Physiol. 2012 Mar 1; 2011 Nov 16. PMID: 22094329

Frucht CS, Uduman M, Kleinstein SH, Santos-Sacchi J, Navaratnam DS: Gene expression gradients along the tonotopic axis of the chicken auditory epithelium. J Assoc Res Otolaryngol. 2011 Aug; 2011 Mar 12. PMID: 21399991

Frucht CS, Santos-Sacchi J, Navaratnam DS: MicroRNA181a plays a key role in hair cell regeneration in the avian auditory epithelium. Neurosci Lett. 2011 Apr 8; 2011 Feb 21. PMID: 21316421

Bai JP, Surguchev A, Navaratnam D: β4-subunit increases Slo responsiveness to physiological Ca2+ concentrations and together with β1 reduces surface expression of Slo in hair cells. Am J Physiol Cell Physiol. 2011 Mar; 2010 Dec 22. PMID: 21178105

Bian S, Bai JP, Chapin H, Le Moellic C, Dong H, Caplan M, Sigworth FJ, Navaratnam DS: Interactions between β-catenin and the HSlo potassium channel regulates HSlo surface expression. PLoS One. 2011; 2011 Dec 14. PMID: 22194818

Bian S, Koo BW, Kelleher S, Santos-Sacchi J, Navaratnam DS: A highly expressing Tet-inducible cell line recapitulates in situ developmental changes in prestin's Boltzmann characteristics and reveals early maturational events. Am J Physiol Cell Physiol. 2010 Oct; 2010 Jul 14. PMID: 20631244

Frucht CS, Uduman M, Duke JL, Kleinstein SH, Santos-Sacchi J, Navaratnam DS: Gene expression analysis of forskolin treated basilar papillae identifies microRNA181a as a mediator of proliferation. PLoS One. 2010 Jul 9; 2010 Jul 9. PMID: 20634979

Bai JP, Surguchev A, Bian S, Song L, Santos-Sacchi J, Navaratnam D: Combinatorial cysteine mutagenesis reveals a critical intramonomer role for cysteines in prestin voltage sensing. Biophys J. 2010 Jul 7. PMID: 20655836

Bai JP, Surguchev A, Ogando Y, Song L, Bian S, Santos-Sacchi J, Navaratnam D: Prestin surface expression and activity are augmented by interaction with MAP1S, a microtubule-associated protein. J Biol Chem. 2010 Jul 2; 2010 Apr 23. PMID: 20418376

Brown MR, Kronengold J, Gazula VR, Chen Y, Strumbos JG, Sigworth FJ, Navaratnam D, Kaczmarek LK: Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack. Nat Neurosci. 2010 Jul; 2010 May 30. PMID: 20512134

Bai JP, Surguchev A, Montoya S, Aronson PS, Santos-Sacchi J, Navaratnam D: Prestin's anion transport and voltage-sensing capabilities are independent. Biophys J. 2009 Apr 22. PMID: 19383462

Navaratnam DS: Yeast two-hybrid screening to test for protein-protein interactions in the auditory system. Methods Mol Biol. 2009. PMID: 18839352

Bai JP, Navaratnam D, Samaranayake H, Santos-Sacchi J: En block C-terminal charge cluster reversals in prestin (SLC26A5): effects on voltage-dependent electromechanical activity. Neurosci Lett. 2006 Sep 1; 2006 Jul 12. PMID: 16839688

Santos-Sacchi J, Rybalchenko V, Bai JP, Song L, Navaratnam D: On the temperature and tension dependence of the outer hair cell lateral membrane conductance GmetL and its relation to prestin. Pflugers Arch. 2006 Jun; 2006 Mar 7. PMID: 16521020

Navaratnam D, Bai JP, Samaranayake H, Santos-Sacchi J: N-terminal-mediated homomultimerization of prestin, the outer hair cell motor protein. Biophys J. 2005 Nov; 2005 Aug 19. PMID: 16113116

Samaranayake H, Saunders JC, Greene MI, Navaratnam DS: Ca(2+) and K(+) (BK) channels in chick hair cells are clustered and colocalized with apical-basal and tonotopic gradients. J Physiol. 2004 Oct 1; 2004 Jul 22. PMID: 15272029