Mothes, Walther H

Associate Professor of Microbial Pathogenesis

Biography

Dr. Mothes studied chemistry (Diploma 1993) and received a Ph.D. in cell biology (Humboldt-University Berlin, 1998) for his studies on protein secretion and membrane protein integration at the endoplasmic reticulum under the mentorship of Dr. Tom Rapoport at Harvard Medical School. He worked as a postdoctoral fellow with Dr. John Young and James Cunningham on retroviral entry before he started his own laboratory at Yale University in 2001. Dr. Mothes was promoted to Associate Professor in...

Dr. Mothes studied chemistry (Diploma 1993) and received a Ph.D. in cell biology (Humboldt-University Berlin, 1998) for his studies on protein secretion and membrane protein integration at the endoplasmic reticulum under the mentorship of Dr. Tom Rapoport at Harvard Medical School. He worked as a postdoctoral fellow with Dr. John Young and James Cunningham on retroviral entry before he started his own laboratory at Yale University in 2001. Dr. Mothes was promoted to Associate Professor in 2007 and received Tenure in 2011.

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Ma, Xiaochu

Graduate Student in Microbiology

I joined our lab in 2013 and my current project is using single molecule FRET to detect the conformational dynamics of the HIV-1 envelope protein, I'm focusing on the CCR5-tropic HIV-1 isolates and their behaviors during viral entry.

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Munro, James B.

Postdoctoral Fellow in Microbial Pathogenesis

I have a Ph.D. in biophysics and I am thrilled to be able to apply single molecule FRET imaging to various aspects of the HIV life cylce including entry and assembly.

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Pi, Ruoxi

Graduate Student in Microbial Pathogenesis

I am happy to be in the Mothes Lab and work on visualizing viral particles capture and spread in vivo. I am interested in studying cell types and molecular mechanisms involved in these events.

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Sewald, Franz Xaver

Associate Research Scientist in Microbial Pathogenesis

The Mothes lab thought that it is cool to images retroviruses in HEK293 cells, but the relevance was unclear. Thus, I am happy to report that we can visualize virally infected cells directly in living animals.

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Uchil, Pradeep Devappa

Associate Research Scientist in Microbial Pathogenesis

I am studying the antiviral roles of various TRIM proteins. In addition I will concentrate more on the interface between basic and translational research.

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Ventura, John

Graduate Student in the Department of Cell Biology

Retroviruses are astonishing for many reasons: their utterly fascinating life cycle, their ability to drive evolutionary change in their hosts following generations of infection, and the potent clinical threat they pose to a great many people word-wide.   After acceptance into the BBS PhD program, I was instantly drawn to the Mothes Lab because of their striking work in retroviral intercellular transmission and their use of two-photon microscopy; it is a...

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Agosto, Luis

Postdoc in Andy Henderson's lab at BU

    Chan, Wai-Tsing

    Consultant in Biotech Industry

      Herrmann, Christin

      Graduate student at UPenn

        Hinz, Angelika

        Graduate Student

          Jin, Jing

          Postdoc in Graham Simmons's lab at UCSF

            Lehmann, Maik

            Group Leader

              Li, Fei

              Living in Beijing

                Liu, Shan

                PhD Student

                  Luna, Joseph

                  Graduate Student

                    Oztop, Ilker

                    Graduate Student

                      Pawliczek, Tobias

                      Patent and Analytical Scientist

                        Quinlan, Brian

                        Graduate Student

                          Rompf, Maria

                          Graduate Student

                            Sherer, Nathan

                            Assistant Professor

                              Siegel, Steven

                              MD/PhD Student

                                Symington, Jane

                                MD/PhD Student

                                  Truong, Rosaline

                                  Working in California

                                    Zhong, Peng

                                    Employee