Slide 14

Immunochemical Stain for GABA Illustrating the PGN and Intrageniculate interneurons

Thalamic and thalamocortical activity, of course, is not dictated by the properties of single cells alone. These cells also interact in networks to generate the various complicated patterns of the EEG. We have found that the geniculate slice maintains the necessary connections to generate one of these patterns of activity: spindle waves. Immunocytochemical staining for the inhibitory neurotransmitter GABA reveals the perigeniculate nucleus (to the left) in this sagital slice of the geniculate.