Slide 10

Removing gNa+ from the Soma Reveals the Axonal Basis of the Kink

Figure 10. A, D. Axonal and somatic spikes before (blue) and after (red) removing gNa+ from the soma. Note that the residual spike in the soma results from the back-propagation of the axonal spike. B,E. dV/dt of the spikes in the axon and soma before and after removing gNa+ from the soma. Note that the initial component of the spike dV/dt in the soma results entirely from the spike in the axon. C,F. Phase plot of spike dV/dt versus Vm for the axonal and somatic spikes before and after removal of gNa+ from the soma. Note that the rising phase of the phase plot in the soma is mediated entirely by the spike in the axon.