Slide 8

Schematic of the different cell types and connections in the cerebral cortex

Long-range synchronized activity is typically associated with repetitive burst firing in single cortical neurons at 30-70 Hz. Who are these neurons that generate this unusual pattern of activity? The neocortex is filled with multiple cell types, including pyramidal and non-pyramidal cells arranged in various layers (I, II, III, IV, V, and VI). We sought to determine the cells that may be generating stimulus-induced repetitive burst discharges through intracellular recordings in vivo.
From Szentagothai, J. (1977) The neuron network of the cerebral cortex: a functional interpretation. Proc. R. Soc. Lond. B 201: 219-248.