Slide 8

Application of a sinewave field strongly modulates the timing of network activity

Figure 8. Extracellular multiple unit recording illustrating the cortical network activity of the slow oscillationin the absence of an electric field (black, top; dashed sinewave is for illustration only) and in the presence of a sinewave (red below). During the presentation of the sinewave, the slow oscillation phase locks to the beginning of the EF. Examining the autocorrelation of the multiple unit activity illustrates the enhanced oscillatory nature of the network activity (increased sideband peaks; red line).

  • Sine-wave EF modulates ongoing slow oscillation
  • Increased sideband (SB) to central peak (CP) ration indicates enhanced SO.