Slide 9

The influence of changes in synaptic activity on action potential responses was examined by injecting actual synaptic responses recorded in real neurons into a model neuron

Figure 9. Do the changes we observe in synaptic potentials explain the increase in sparseness and reliability of action potential responses? Here we examined this question by injecting actual synaptic potential (EPSP and IPSP) traces recorded from individual trials in vivo into a model leaky integrate and fire model cell. We mixed together EPSP and IPSP responses from different conditions to see which would give us the observed effects on action potential responses.