Slide 12

Inhibitory postsynaptic potentials contribute most to sparseness while excitatory postsynaptic potentials contribute most to reliability

Figure 12. A. Injection of EPSPs and IPSPs from CRF+nCRF results in a marked increase in sparseness. A similar effect is seen with IPSPs from nCRF+CRF plus EPSPs from CRF, but not visa versa. B. Spike reliability is also increased with injection of EPSPs and IPSPs from CRF+nCRF trials. This effect is replicated with EPSPs from these trials, but less with IPSPs from CRF+nCRF trials. C. The similarity betwen PSTH responses between the different conditions reveal that the EPSPs carry a high degree of similarity, with the IPSPs contributing less.