The brain consists of numerous interconnected parts. In the human, the cerebral cortex is the most expansive and important component. The human cortex consists of two large sheets (each about the size of a large pizza), of which the cell layer is about 2 mm thick (upper right). A Golgi stain of the cortex reveals that it consists of a meshwork of highly interconnected neurons (lower left). Each pyramidal cell receives input from approximately 10,000 to 30,000 other cortical neurons. In particular cortical pyramidal cells (lower middle) are highly interconnected, particularly with neighboring pyramidal and non-pyramidal cells. Traditionally, pyramidal cells are believed to receive input on their dendrites and cell bodies and generate patterns of action potentials at their axon initial segments (lower right) and communicate this information to the next neurons through the action potential-dependent release of transmitter.
Here we demonstrate that this may be an overly simplified view of information communication in the brain.
How will my information be used?
When you express interest in a specific study, the information from your profile will be sent to the doctor conducting that study. If you're eligible to participate, you may be contacted by a nurse or study coordinator.
If you select a health category rather than a specific study, doctors who have active studies in that area may contact you to ask if you would like to participate.
In both cases, you will be contacted by the preferred method (email or phone) that you specified in your profile.