Leadership


Joseph Anthony Madri

Professor of Pathology

Professor of Pathology; Director of Education

Members

Michael Centrella

Senior Research Scientist in Pathology

Research Interests:Molecular aspects of bone growth factor and receptor expression and activity; control of protein synthesis initiation

Qi Li

Associate Research Scientist in Pediatrics (Nephrology)

Research Interests:Cell- Matrix and Cell-Cell Interactions; Integrin-Mediated Signaling. Neural Stem cell development.

Thomas L McCarthy

Research Scientist in Pathology

Research Interests:Hormonal and molecular control of IGF-I expression and TGF-b function in osteoblasts; osteoblast gene expression, including steroid hormone interactions with signaling pathways that control gene expression; native and synthetic sex steroid metabolism by osteoblasts, including synthesis of a selective estrogen receptor modulator by aging osteoblast cultures; interactions of protein kinases and steroid hormones as they affect gene expression

Recent Former Lab Members

Jaime Liu - Visiting Scientist, China
Jaime, an Associate Professor at Jinlin University, China, investigated the effects of endothelial derived soluble factors (BDNF, VEGF and SDF-1) on the migratory and differentiation behaviors of neural stem cells in direct contact and non-contact co-cultures.
Jennifer Long - Former Graduate Student, Cellular and Molecular Physiology
Jennifer Long (now Baughman). Jennifer investigated the molecular mechanisms of vascular sympathetic innervation. Specifically she identified attractive and repulsive signaling molecules differentially expressed by innervated and non-innervated vessels using traditional cell biological and pharmacological methods and suppressive hybridization techniques to identify novels signaling molecules involved in this process. The importance of understanding and controlling sympathetic innervation in specific vascular beds is thought to be important and may have important clinical implications in a variety of clinical settings including its disruption following heart transplantation. She is currently a postdoctoral fellow at Harvard University.
Anjali Nath, Ph.D. - Former Graduate Student, Cellular and Molecular Physiology
Anjali demonstrated the effectiveness of a protein profiling approach in the identification of novel proteins involved in epithelial to mesenchymal transformation in the cardiac cushions during heart development and is elucidating the signaling pathways that a selected number of these proteins play roles in. She is currently a postdoctoral fellow at Harvard University.