Select Publications

  1. Bilguvar K, Tyagi NK, Ozkara C, Tuysuz B, Bakircioglu M, Choi M, Delil S, Caglayan AO, Baranoski JF, Erturk O, Yalcinkaya C, Karacorlu M, Dincer A, Johnson MH, Mane S, Chandra SS, Louvi A, Boggon TJ, Lifton RP, Horwich AL, Gunel M. (2013) Recessive loss of function of the neuronal ubiquitin hydrolase UCHL1 leads to early-onset progressive neurodegeneration. Proc. Natl. Acad. Sci. USA, 110(9):3489-94.
  2. Louvi, A.* and Artavanis-Tsakonas, S.* (2012). Notch and disease: A growing field. Semin. Cell Dev. Biol 23(4):473-80.
  3. Fre, S., Hannezo, E., Sale, S., Huyghe, M., Lafkas, D., Kissel, H., Louvi, A., Greve, J., Louvard, D., and Artavanis-Tsakonas, S. (2011) Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice. PLoS ONE, 6:e25785.
  4. Barak, T.*, Kwan, K. Y.*, Louvi, A., Demirbilek, V., Saygı, S., Tüysüz, B., Choi, M., Boyacı, H., Doerschner, K., Zhu, Y., Kaymakçalan, H., Yılmaz, S., Bakırcıoğlu, M., Çağlayan, A. O., Öztürk, A. K., Yasuno, K., Brunken, W. J., Atalar, E., Yalçınkaya, C., Dinçer, A., Bronen, R. A., Mane, S., Özçelik, T., Lifton, R. P., Šestan, N., Bilgüvar, K., and Günel, M. (2011). Recessive laminin g3 mutations cause malformations of occipital cortical development. Nat. Genet. 43, 590-594.
  5. Arboleda-Velasquez, J. F., Manent, J., Lee, J. H., Tikka, S., Ospina, C., Vanderburg, C. R., Frosch, M., Rodríguez-Falcón, M., Villen, J., Gygi, S., Lopera, F., Kalimo, H., Moskowitz, M., Ayata, C., Louvi, A.*, and Artavanis-Tsakonas, S.* (2011). Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease. Proc. Natl. Acad. Sci. USA. 108, E128-135.
  6. Louvi, A. and Grove, E.A. (2011). Cilia in the CNS: the Quiet Organelle Claims Center Stage. Neuron 69, 1046-1060. PMC3070490
  7. Louvi, A.*, Chen, L., Two, A. M., Zhang, H., Min, W., and Günel, M.* (2011). Loss of cerebral cavernous malformation 3 (Ccm3) in neuroglia leads to CCM and vascular pathology. Proc. Natl. Acad. Sci. USA. 108, 3737-3742.
  8. Oztürk, A.K., Louvi, A., and Günel, M. (2011). Genetics of Cerebral Cavernous Malformations. Youmans Neurological Surgery. Elsevier.
  9. Bilgüvar, K.*, Oztürk, A. K.*, Louvi, A., Kwan, K. Y., Choi, M., Tatlı, B., Yalnızoğlu, D., Tüysüz, B., Cağlayan, A. O., Gökben, S., Kaymakçalan, H., Barak, T., Bakırcıoğlu, M., Yasuno, K., Ho, W., Sanders, S., Zhu, Y., Yılmaz, S., Dinçer, A., Johnson, M. H., Bronen, R. A., Koçer, N., Per, H., Mane, S., Pamir, M. N., Yalçınkaya, C., Kumandaş, S., Topçu, M., Ozmen, M., Sestan, N., Lifton, R. P., State, M. W., and Günel, M. (2010). Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations. Nature 467, 207-210.
  10. Ercan-Sencicek A. G., Stillman A. A., Ghosh A. K., Bilgüvar K., O'Roak B. J., Mason C. E., Abbott T., Gupta A., King R. A., Pauls D. L., Tischfield J. A., Heiman G. A., Singer H. S., Gilbert D. L., Hoekstra P. J., Morgan T. M., Loring E., Yasuno K., Fernandez T., Sanders S., Louvi A., Cho J. H., Mane S., Colangelo C. M., Biederer T., Lifton R. P., Günel M., and State M. W. (2010).  L-Histidine decarboxylase and Tourette’s syndrome. N. Engl. J. Med., 362:1901-1908.
  11. Chen, L., Tanriover, G., Yano, H., Friedlander, R., Louvi, A. and Gunel, M. (2009). Apoptotic functions of CCM3/PDCD10, the gene mutated in cerebral cavernous malformation 3. Stroke, 40, 1474-1481.
  12. Stillman, A., Krsnik, Z., Sun, J., Rasin, M.-R., State, M. W., Sestan, N., and Louvi, A. (2009). Developmentally regulated and evolutionarily conserved expression of SLITRK1 in brain circuits implicated in Tourette syndrome. J. Comp. Neurol., 513, 21-37. NIHMSID83721
  13. Tanriover, G., Boylan, A. J., DiLuna, M. L., Pricola, K. L., Louvi, A., and Gunel, M. (2008). PDCD10, the gene mutated in Cerebral Cavernous Malformation 3 (CCM3) is expressed in the neurovascular unit. Neurosurgery 62, 930-938.
  14. Bakkaloglu, B., O’Roak, B.J., Louvi, A., Gupta, A.R., Abelson, J.F., Morgan, T.T., Chawarska, K., Klin, A., Ercan-Sencicek, A. G., Stillman, A.A., Tanriover, G., Abrahams, B.S., Duvall, J.A., Robbins, E.M., Geschwind, D.H., Biederer, T., Gunel, M., Lifton, R.P. and State, M.W. (2008). Molecular cytogenetic analysis and re-sequencing of Contactin Associated Protein-like 2 in Autism Spectrum Disorders. Am. J. Hum. Genet. 82, 165-173.
  15. Louvi, A.*, Yoshida, M., and Grove, E.A. (2007). The derivatives of the Wnt3a lineage in the central nervous system. J. Comp. Neurol. 504, 550-569.
  16. Louvi, A. and Artavanis-Tsakonas, S. (2006). Notch signalling in vertebrate neural development. Nat. Rev. Neurosci. 7, 93-102.
  17. Louvi, A., Arboleda-Velasquez, J., and Artavanis-Tsakonas, S. (2006). CADASIL: a critical look at a Notch disease. Dev. Neurosci. 28, 5-12.
  18. Abelson, J. F., Kwan K. Y., O'Roak B. J., Baek, D. Y., Stillman, A. A., Morgan, T. M., Mathews, C. A., Pauls, D. L., Rasin, M.-R., Gunel, M., Davis, N. R., Ercan-Sencicek, A. G., Guez, D. H., Spertus, J. A., Leckman, J. F., Dure, L. S., Kurlan, R., Singer, H. S., Gilbert, D. L., Farhi, A., Louvi, A., Lifton, R.P., Sestan, N., and State, M.W. (2005). Sequence Variants in SLITRK1 Are Associated with Tourette Syndrome. Science 310, 317-320.
  19. Louvi, A.*, Sisodia, S.S., and. Grove, E.A. (2004). Presenilin 1 in migration and morphogenesis in the central nervous system. Development 131, 3093-3105.
  20. Louvi, A., Alexandre, P., Métin, C., Wurst, W., and Wassef, M. (2003). The isthmic neuroepithelium is essential for cerebellar  midline fusion. Development 130, 5319-5330.