Publications

Longerich S, Kwon Y, Tsai MS, Hlaing AS, Kupfer GM and Sung P: Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA. Nucleic Acids Res. 2014;42 (9) :5657-70. Epub 2014 Mar 12. PMID: 24623813

Kupfer GM: Fanconi anemia: a signal transduction and DNA repair pathway. Yale J Biol Med. 2013 Dec 13;86 (4) :491-7. Epub 2013 Dec 13. PMID: 24348213


Chirnomas SD and Kupfer GM: The inherited bone marrow failure syndromes. Pediatr Clin North Am. 2013 Dec;60 (6) :1291-310. PMID: 24237972

Omer B, Kadan-Lottick NS, Roberts KB, Wang R, Demsky C, Kupfer GM, Cooper D, Seropian S and Ma X: Patterns of subsequent malignancies after Hodgkin lymphoma in children and adults. Br J Haematol. 2012 Sep;158 (5) :615-25. Epub 2012 Jul 6. PMID: 22775513


Lo SM, Choi M, Liu J, Jain D, Boot RG, Kallemeijn WW, Aerts JM, Pashankar F, Kupfer GM, Mane S, Lifton RP and Mistry PK: Phenotype diversity in type 1 Gaucher disease: discovering the genetic basis of Gaucher disease/hematologic malignancy phenotype by individual genome analysis. Blood. 2012 May 17;119 (20) :4731-40. Epub 2012 Apr 4. PMID: 22493294

Williams SA, Wilson JB, Clark AP, Mitson-Salazar A, Tomashevski A, Ananth S, Glazer PM, Semmes OJ, Bale AE, Jones NJ and Kupfer GM: Functional and physical interaction between the mismatch repair and FA-BRCA pathways. Hum Mol Genet. 2011 Nov 15;20 (22) :4395-410. Epub 2011 Aug 24. PMID: 21865299


Williams SA, Longerich S, Sung P, Vaziri C and Kupfer GM: The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI. Blood. 2011 May 12;117 (19) :5078-87. Epub 2011 Feb 25. PMID: 21355096

Song IY, Palle K, Gurkar A, Tateishi S, Kupfer GM and Vaziri C: Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway. J Biol Chem. 2010 Oct 8;285 (41) :31525-36. Epub 2010 Jul 30. PMID: 20675655


Halene S, Gao Y, Hahn K, Massaro S, Italiano JE Jr, Schulz V, Lin S, Kupfer GM and Krause DS: Serum response factor is an essential transcription factor in megakaryocytic maturation. Blood. 2010 Sep 16;116 (11) :1942-50. Epub 2010 Jun 4. PMID: 20525922


Wilson JB, Blom E, Cunningham R, Xiao Y, Kupfer GM and Jones NJ: Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance. Mutat Res. 2010 Jul 7;689 (1-2) :12-20. Epub 2010 May 5. PMID: 20450923


Zhi G, Chen X, Newcomb W, Brown J, Semmes OJ and Kupfer GM: Purification of FANCD2 sub-complexes. Br J Haematol. 2010 Jul;150 (1) :88-92. Epub 2010 Apr 29. PMID: 20456353

Zhi G, Wilson JB, Chen X, Krause DS, Xiao Y, Jones NJ and Kupfer GM: Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction. Cancer Res. 2009 Nov 15;69 (22) :8775-83. Epub 2009 Oct 27. PMID: 19861535


Noy-Lotan S, Dgany O, Lahmi R, Marcoux N, Krasnov T, Yissachar N, Ginsberg D, Motro B, Resnitzky P, Yaniv I, Kupfer GM and Tamary H: Codanin-1, the protein encoded by the gene mutated in congenital dyserythropoietic anemia type I (CDAN1), is cell cycle-regulated. Haematologica. 2009 May;94 (5) :629-37. Epub 2009 Mar 31. PMID: 19336738


Green AM and Kupfer GM: Fanconi anemia. Hematol Oncol Clin North Am. 2009 Apr;23 (2) :193-214. PMID: 19327579


Collins NB, Wilson JB, Bush T, Thomashevski A, Roberts KJ, Jones NJ and Kupfer GM: ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function. Blood. 2009 Mar 5;113 (10) :2181-90. Epub 2008 Dec 24. PMID: 19109555

Durkin SS, Guo X, Fryrear KA, Mihaylova VT, Gupta SK, Belgnaoui SM, Haoudi A, Kupfer GM and Semmes OJ: HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase. J Biol Chem. 2008 Dec 26;283 (52) :36311-20. Epub 2008 Oct 27. PMID: 18957425


Qi L, Cazares L, Johnson C, de Alarcon P, Kupfer GM and Semmes OJ: Serum protein expression profiling in pediatric Hodgkin lymphoma: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2008 Aug;51 (2) :216-21. PMID: 18421715


Mihaylova VT, Green AM, Khurgel M, Semmes OJ and Kupfer GM: Human T-cell leukemia virus I tax protein sensitizes p53-mutant cells to DNA damage. Cancer Res. 2008 Jun 15;68 (12) :4843-52. PMID: 18559532

Machida YJ, Machida Y, Chen Y, Gurtan AM, Kupfer GM, D'Andrea AD and Dutta A: UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation. Mol Cell. 2006 Aug;23 (4) :589-96. PMID: 16916645


Hussain S, Wilson JB, Blom E, Thompson LH, Sung P, Gordon SM, Kupfer GM, Joenje H, Mathew CG and Jones NJ: Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2. DNA Repair (Amst). 2006 May 10;5 (5) :629-40. Epub 2006 Apr 18. PMID: 16621732

Collins N and Kupfer GM: Molecular pathogenesis of Fanconi anemia. Int J Hematol. 2005 Oct;82 (3) :176-83. PMID: 16207587


Mi J and Kupfer GM: The Fanconi anemia core complex associates with chromatin during S phase. Blood. 2005 Jan 15;105 (2) :759-66. Epub 2004 Jul 15. PMID: 15256425

Qiao F, Mi J, Wilson JB, Zhi G, Bucheimer NR, Jones NJ and Kupfer GM: Phosphorylation of fanconi anemia (FA) complementation group G protein, FANCG, at serine 7 is important for function of the FA pathway. J Biol Chem. 2004 Oct 29;279 (44) :46035-45. Epub 2004 Aug 6. PMID: 15299017


Mi J, Qiao F, Wilson JB, High AA, Schroeder MJ, Stukenberg PT, Moss A, Shabanowitz J, Hunt DF, Jones NJ and Kupfer GM: FANCG is phosphorylated at serines 383 and 387 during mitosis. Mol Cell Biol. 2004 Oct;24 (19) :8576-85. PMID: 15367677


Thomashevski A, High AA, Drozd M, Shabanowitz J, Hunt DF, Grant PA and Kupfer GM: The Fanconi anemia core complex forms four complexes of different sizes in different subcellular compartments. J Biol Chem. 2004 Jun 18;279 (25) :26201-9. Epub 2004 Apr 13. PMID: 15082718