Research

List of Current Projects

  • In silico de-mixing of genomics signals from heterogeneous tumor cell populations into their leading subclonal components (http://arxiv.org/abs/1301.1966)
  • Boosting software tool performance via effective validations and crowd-sourcing (http://arxiv.org/abs/1303.3257 and http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192143/)
  • Cancer biomarker discovery in whole-exome sequencing, RNA-Seq and immunohistochemistry
  • Approaches for studying the epigenetic landscape at different length scales
  • Combining 4C-seq, FISH and epigenetics for studying translocations in immune cells
  • Making sense of diversity of mutation profiles within specific cancer populations
  • Event detection in genomics data
  • Nonlinear dimensional reduction approaches for detecting genomic patterns
  • Inferring isoform usage by combining RNA-seq profiles from multiple states
  • Building user-friendly frameworks for ChIP-Seq analysis