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Publications

  1. C. Zhang, B. Balbo, M. Ma, J. Zhao, X. Tian, Y. Kluger, and S. Somlo, "Cyclin-Dependent Kinase 1 Activity Is a Driver of Cyst Growth in Polycystic Kidney Disease," Journal of the American Society of Nephrology, vol. 32, pp. 41-51, 2021.
  2. E. Sefik, B. Israelow, J. Zhao, R. Qu, E. Song, H. Mirza, E. Kaffe, S. Halene, E. Meffre, and Y. Kluger, "A humanized mouse model of chronic COVID-19 to evaluate disease mechanisms and treatment options," 2021.
  3. M. S. B. Raredon, J. Yang, J. Garritano, M. Wang, D. Kushnir, J. C. Schupp, T. S. Adams, A. M. Greaney, K. L. Leiby, N. Kaminski, Y. Kluger, A. Levchenko, and L. E. Niklason, "Connectome: computation and visualization of cell-cell signaling topologies in single-cell systems data," bioRxiv, p. 2021.01.21.427529, 2021.
  4. T. Qing, H. Mohsen, V. L. Cannataro, M. Marczyk, M. Rozenblit, J. Foldi, M. F. Murray, J. P. Townsend, Y. Kluger, and M. Gerstein, "Cancer relevance of human genes," bioRxiv, 2021.
  5. Lindenbaum, N. Nouri, Y. Kluger, and S. H. Kleinstein, "Alignment free identification of clones in B cell receptor repertoires," Nucleic Acids Res, vol. 49, p. e21, Feb 26 2021.
  6. Y.-W. E. Lin, T. Shnitzer, R. Talmon, F. Villarroel-Espindola, S. Desai, K. Schalper, and Y. Kluger, "Graph of graphs analysis for multiplexed data with application to imaging mass cytometry," PLOS Computational Biology, vol. 17, p. e1008741, 2021.
  7. B. Landa, T. T. Zhang, and Y. Kluger, "Biwhitening Reveals the Rank of a Count Matrix," arXiv preprint arXiv:2103.13840, 2021.
  8. B. Landa, R. R. Coifman, and Y. Kluger, "Doubly Stochastic Normalization of the Gaussian Kernel Is Robust to Heteroskedastic Noise," SIAM Journal on Mathematics of Data Science, pp. 388-413, 2021/01/01 2021.
  9. A. Jaffe, N. Amsel, Y. Aizenbud, B. Nadler, J. T. Chang, and Y. Kluger, "Spectral Neighbor Joining for Reconstruction of Latent Tree Models," SIAM Journal on Mathematics of Data Science, vol. 3, pp. 113-141, 2021.
  10. Y. Aizenbud, A. Jaffe, M. Wang, A. Hu, N. Amsel, B. Nadler, J. T. Chang, and Y. Kluger, "Spectral Top-Down Recovery of Latent Tree Models," arXiv preprint arXiv:2102.13276, 2021.
  11. J. Zhao, A. Jaffe, H. Li, O. Lindenbaum, E. Sefik, R. Jackson, X. Cheng, R. Flavell, and Y. Kluger, "Detection of differentially abundant cell subpopulations discriminates biological states in scRNA-seq data," bioRxiv, p. 711929, 2020.
  12. H. Zhang, H. Zhu, G. Deng, C. R. Zito, V. O. Oria, C. K. Rane, S. Zhang, S. A. Weiss, T. Tran, A. Adeniran, F. Zhang , J. Zhou, Y. Kluger, M. W. Bosenberg , H. M. Kluger, and L. B. Jilaveanu, "PLEKHA5 regulates tumor growth in metastatic melanoma," Cancer, vol. 126, pp. 1016-1030, 2020.
  13. Y. Yamada, O. Lindenbaum, S. Negahban, and Y. Kluger, "Feature selection using stochastic gates," in International Conference on Machine Learning, 2020, pp. 10648-10659.
  14. M. Roulis, A. Kaklamanos, M. Schernthanner, P. Bielecki, J. Zhao, E. Kaffe, L. S. Frommelt, R. Qu, M. S. Knapp, A. Henriques, N. Chalkidi, V. Koliaraki, J. Jiao, J. R. Brewer, M. Bacher, H. N. Blackburn, X. Zhao, R. M. Breyer, V. Aidinis, D. Jain, B. Su, H. R. Herschman, Y. Kluger, G. Kollias, and R. A. Flavell, "Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche," Nature, vol. 580, pp. 524-529, Apr 2020.
  15. T. Qing, H. Mohsen, M. Marczyk, Y. Ye, T. O’Meara, H. Zhao, J. P. Townsend, M. Gerstein, T. Qing, H. Mohsen, M. Marczyk, Y. Ye, T. O’Meara, H. Zhao, J. P. Townsend, M. Gerstein, C. Hatzis, Y. Kluger, and L. Pusztai, "Germline variant burden in cancer genes correlates with age at diagnosis and somatic mutation burden," Nature communications, vol. 11, pp. 1-8, 2020.
  16. M. Marczyk, G. A. Patwardhan, J. Zhao, R. Qu, X. Li, V. B. Wali, A. K. Gupta, M. M. Pillai, Y. Kluger, Q. Yan, C. Hatzis, L. Pusztai, and V. Gunasekharan, "Multi-Omics Investigation of Innate Navitoclax Resistance in Triple-Negative Breast Cancer Cells," Cancers, vol. 12, p. 2551, 2020.
  17. Lindenbaum, U. Shaham, J. Svirsky, E. Peterfreund, and Y. Kluger, "Let the Data Choose its Features: Differentiable Unsupervised Feature Selection," arXiv preprint arXiv:2007.04728, 2020.
  18. Lindenbaum, M. Salhov, A. Averbuch, and Y. Kluger, "Deep Gated Canonical Correlation Analysis," arXiv preprint arXiv:2010.05620, 2020.
  19. B. Landa, R. Qu, J. Chang, and Y. Kluger, "Local Two-Sample Testing over Graphs and Point-Clouds by Random-Walk Distributions," arXiv preprint arXiv:2011.03418, 2020.
  20. D. M. Kluger, Y. Aizenbud, A. Jaffe, F. Parisi, L. Aizenbud, E. Minsky-Fenick, J. M. Kluger, S. Farhadian, H. M. Kluger, and Y. Kluger, "Impact of healthcare worker shift scheduling on workforce preservation during the COVID-19 pandemic," Infection Control & Hospital Epidemiology, vol. 41, pp. 1443-1445, 2020.
  21. A.Jarret, R. Jackson, C. Duizer, M. E. Healy, J. Zhao, J. M. Rone, P. Bielecki, E. Sefik, M. Roulis, T. Rice, K. N. Sivanathan, T. Zhou, A. G. Solis, H. Honcharova-Biletska, K. Vélez, S. Hartner, J. S. Low, R. Qu, M. R. de Zoete, N. W. Palm, A. M. Ring, A. Weber, A. E. Moor, Y. Kluger, R. Nowarski, and R. A. Flavell, "Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity," Cell, vol. 180, pp. 50-63.e12, 2020/01/09/ 2020.
  22. A. Jaffe, Y. Kluger, G. C. Linderman, G. Mishne, and S. Steinerberger, "Randomized near-neighbor graphs, giant components and applications in data science," Journal of applied probability, vol. 57, pp. 458-476, 2020.
  23. A. Jaffe, Y. Kluger, O. Lindenbaum, J. Patsenker, E. Peterfreund, and S. Steinerberger, "The Spectral Underpinning of word2vec," Frontiers in Applied Mathematics and Statistics, vol. 6, 2020-December-03 2020.
  24. S. B. Goldberg, K. A. Schalper, S. N. Gettinger, A. Mahajan, R. S. Herbst, A. C. Chiang, R. Lilenbaum, F. H. Wilson, S. B. Omay, J. B. Yu, L. Jilaveanu, T. Tran, K. Pavlik, E. Rowen, H. Gerrish, A. Komlo, R. Gupta, H. Wyatt, M. Ribeiro, Y. Kluger, G. Zhou, W. Wei, V. L. Chiang, and H. M. Kluger, "Pembrolizumab for management of patients with NSCLC and brain metastases: long-term results and biomarker analysis from a non-randomised, open-label, phase 2 trial," The Lancet Oncology, vol. 21, pp. 655-663, 2020/05/01/ 2020.