People
Hochstrasser, Mark
Eugene Higgins Professor of Molecular Biophysics and Biochemistry and Professor of Molecular, Cellular, and Developmental Biology
Biography
Part of the Yale faculty since 2000, Prof. Mark Hochstrasser holds appointments in the Department of Molecular Biophysics and Biochemistry, the Department of Molecular, Cellular and Developmental Biology and the School of Medicine’s Biological and Biomedical Sciences Program. He earned his B.A. at Rutgers University and his Ph.D. at the University of California, San Francisco, and conducted postdoctoral research at the Massachusetts Institute of Technology. He has earned numerous honors for...
Part of the Yale faculty since 2000, Prof. Mark Hochstrasser holds appointments in the Department of Molecular Biophysics and Biochemistry, the Department of Molecular, Cellular and Developmental Biology and the School of Medicine’s Biological and Biomedical Sciences Program. He earned his B.A. at Rutgers University and his Ph.D. at the University of California, San Francisco, and conducted postdoctoral research at the Massachusetts Institute of Technology. He has earned numerous honors for his scientific contributions, including a Young Investigator Award from the Cancer Research Foundation and designation as a Searle Scholar and a Fletcher Scholar. Prof. Hochstrasser holds two patents related to this work, which has been published in numerous scientific and medical journals, including Nature, the Journal of Cell Biology, Cell, the Proceedings of the National Academy of Sciences, Genetics and Nature Cell Biology. A member of the editorial board/virtual faculty of the Targeted Proteins Database and the journal Cell, Hochstrasser has served on several National Institutes of Health study sections. He is a member of the American Society for Biochemistry and Molecular Biology, the American Association for the Advancement of Science and the American Society for Microbiology.
- Email: mark.hochstrasser@yale.edu
Hickey, Christopher
Postdoctoral Fellow in Molecular Biophysics and Biochemistry
Li, Yanjie
Postdoctoral Fellow in Molecular Biophysics and Biochemistry
Padmanabhan, Achuth
Postdoctoral Associate in Molecular Biophysics and Biochemistry
Sakata, Eri
Postdoctoral Associate in Molecular Biophysics and Biochemistry
Tomko, Robert, Jr.
Postdoctoral Fellow in Molecular Biophysics and Biochemistry
Jennifer Gillies
Graduate Students
Regulation of sumoylation and desumoylation
B.Sc. University of Pittsburgh
Publications- A new class of SUMO proteases.Gillies J, Hochstrasser M. EMBO Rep. 2012 Apr 2;13(4):284-5.
Mary Kunjappu
Graduate Student
Assembly of 20S Proteasome
B.A. Barnard College, Columbia University
Publications- A conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor binding. Kusmierczyk AR, Kunjappu MJ, Kim RY, Hochstrasser M. Nat Struct Mol Biol. 2011 May;18(5):622-9.
- A multimeric assembly factor controls the formation of alternative 20S proteasomes.Kusmierczyk AR, Kunjappu MJ, Funakoshi M, Hochstrasser M. Nat Struct Mol Biol. 2008 Mar;15(3):237-44.
Maria Bebiana Vigário da Silva Sá Moura
Graduate Student - GABBA Program
Functional and biological characterization of a novel arsenite-induced protein
M.Sc. Universidade do Porto
Nicole Wilson
Graduate Student
Cellular functions of SUMO
B.S. Brown University
Publications- Function and regulation of SUMO proteases.;Hickey CM,Wilson NR, Hochstrasser M. Nat Rev Mol Cell Biol. 2012 Nov 23;13(12):755-66.
- Desumoylation of the endoplasmic reticulum membrane VAP family protein Scs2 by Ulp1 and SUMO regulation of the inositol synthesis pathway.Felberbaum R, Wilson NR, Cheng D, Peng J, Hochstrasser M. Mol Cell Biol. 2012 Jan;32(1):64-75.
- Incidence and persistence of 8-oxo-7,8-dihydroguanine within a hairpin intermediate exacerbates a toxic oxidation cycle associated with trinucleotide repeat expansion.Jarem DA, Wilson NR, Schermerhorn KM, Delaney S. DNA Repair (Amst). 2011 Aug 15;10(8):887-96.
- Structure-dependent DNA damage and repair in a trinucleotide repeat sequence.Jarem DA, Wilson NR, Delaney S.Biochemistry. 2009 Jul 21;48(28):6655-63.
Dimitrios Zattas
Graduate Student
Structure-function of the yeast Doa10 E3 ligase
B.Sc. University of Thessaly
Publications- Identification and in vitro characterization of follicle stimulating hormone (FSH) receptor variants associated with abnormal ovarian response to FSH. Gerasimova T, Thanasoula MN, Zattas D, Seli E, Sakkas D, Lalioti MD. J Clin Endocrinol Metab. 2010 Feb;95(2):529-36
Noah Steinfeld
Undergraduate Researcher
Functional and Biological Characterization of a Novel Arsenite-Induced Protein
Claire Donnelly
Undergraduate Researcher
MATalpha2 degradation
Undergraduate Researcher
Assembly of the 19S Regulatory Particle Lid Complex
FORMER STUDENTS:
Arendt, Casey S.
Triathalon coach
Austin, TX
Chen, Ping
Associate Professor
Department of Cell Biology
Emory University School of Medicine
pchen[at]cellbio.emory.edu
Connerly, Pamela L.
Assistant Professor of Biology
Indiana University Southeast (New Albany, IN)
pconnerl[at]ius.edu
Felberbaum, Rachael
Manager of Scientific Communications
Protein Sciences Corporation (Meriden, CT)
Hannich, Thomas
Postdoctoral Fellow (Howard Riezman lab)
Dept. of Biochemistry
University of Geneva (Switzerland)
Johnson (Roberts), Phoebe
Associate Research Fellow
Pfizer (Boston)
Kroetz, Mary
Postdoc (David Zarkower lab)
Dept. Genetics, Cell Biology, and Development
University of Minnesota
Lewis, Alaron
Postdoctoral Fellow (Susan Brockerhoff and Rachel Wong labs)
Dept. Biochemistry
University of Washington (Seattle, WA)
alaron[at]u.washington.edu
Papa, Feroz
Associate Professor
Department of Medicine
UCSF (San Francisco, CA)
frpapa[at]medicine.ucsf.edu
Schiffer, Linda
Staff Scientist
Dept. Medicine
University of Illinois (Chicago, IL)
Swanson, Robert
Associate Professor
Department of Biology
Valparaiso University (Valparaiso, IN)
rob.swanson[at]valpo.edu
Swaminathan, Sowmya
Chief Editor
Nature Cell Biology (London, UK)
Xie, Yang
Presidential Postdoctoral Fellow
ovartis Institutes for Biomedical Research (Cambridge, MA)
FORMER POSTDOCS:
Adle, David
Quality Control Scientist
Protein Sciences Corporation (Meriden, CT)
dvdadle[at]gmail.com
Amerik, Alexander (Sasha)
Bloom, Joanna
Scientific Writer
Envision Pharma
joanna.f.bloom[at]gmail.com
Deng, Min
Dentistry Resident (University of Connecticut)
Funakoshi, Minoru
Section of Educational System Center for Faculty Development
Okayama University (Okayama, Japan)
funakosh[at]cc.okayama-u.ac.jp
Kerscher, Oliver
Associate Professor
Department of Biology
College of William & Mary (Williamsburg, VA)
opkers[at]wm.edu
Kreft, Stefan
Junior Group Leader
Dept. of Biochemistry
University Konstanz (Germany)
stefan.kreft[at]uni-konstanz.de
Kusmierczyk, Andrew
Assistant Professor
Department of Biology
Indiana University-Purdue University Indianapolis
akusmier[at]iupui.edu
Laney, Jeff
Assistant Professor
Department of Mol. & Cell. Biology
University of Arizona (Tucson, AZ)
jlaney[at]email.arizona.edu
Li, Shyr-Jiann
Senior Research Scientist
Exelixis, Inc. (South San Francisco, CA)
joli[at]exelixis.com
Li, Xia
Senior Research Associate (Lab of Peter Novick)
Dept. of Cellular & Molecular Medicine
University of California, San Diego
Pals-Rylaarsdam, Robin
Professor
Dept. Biological Science
Benedictine University, (Lisle, IL)
Radke, Susanne
Research Scientist
Kolltan Pharmaceuticals, Inc. (New Haven, CT)
Ravid, Tommer
Assistant Professor
Dept. of Biological Chemistry
Hebrew University (Jerusalem, Israel)
travid[at]cc.huji.ac.il
Eric (V.J.) Rubenstein
Assistant Professor
Department of Biology
Ball State University (Muncie, Indiana)
emrubenstein[at]bsu.edu
Schwartz, David
Data analyst
Bureau of Western Hemisphere Affairs
Department of State (DC)
Su, Dan
Velichutina, Irina
Research Scientist
Albert Einstein College of Medicine
Wang, Lin
Professor
Peking Union Medical College (Beijing, China)
FORMER TECHNICIANS :
Rakhilina, LarissaStaff Scientist
Regeneron Pharmaceuticals (arrytown, NY)
Larissa.Rakhilina[at]regeneron.com
