Publications from PubMed

• The Rosetta Phenotype Harmonization Method Facilitates Finding a Relationship Quantitative Trait Locus for a Complex Cognitive Trait.Petrill SA, Klamer BG, Buyske S, Willcutt EG, Gruen JR, Francis DJ, Flax JF, Brzustowicz LM, Bartlett CW. Genes (Basel). 2023 Aug 31; 2023 Aug 31. PMID: 37761888.
• Author Correction: Discovery of 42 genome-wide significant loci associated with dyslexia.Doust C, Fontanillas P, Eising E, Gordon SD, Wang Z, Alagöz G, Molz B, Pourcain BS, Francks C, Marioni RE, Zhao J, Paracchini S, Talcott JB, Monaco AP, Stein JF, Gruen JR, Olson RK, Willcutt EG, DeFries JC, Pennington BF, Smith SD, Wright MJ, Martin NG, Auton A, Bates TC, Fisher SE, Luciano M. Nat Genet. 2023 Mar. PMID: 36823321.
• Discovery of 42 genome-wide significant loci associated with dyslexia.Doust C, Fontanillas P, Eising E, Gordon SD, Wang Z, Alagöz G, Molz B, Pourcain BS, Francks C, Marioni RE, Zhao J, Paracchini S, Talcott JB, Monaco AP, Stein JF, Gruen JR, Olson RK, Willcutt EG, DeFries JC, Pennington BF, Smith SD, Wright MJ, Martin NG, Auton A, Bates TC, Fisher SE, Luciano M. Nat Genet. 2022 Nov; 2022 Oct 20. PMID: 36266505.
• Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people.Eising E, Mirza-Schreiber N, de Zeeuw EL, Wang CA, Truong DT, Allegrini AG, Shapland CY, Zhu G, Wigg KG, Gerritse ML, Molz B, Alagöz G, Gialluisi A, Abbondanza F, Rimfeld K, van Donkelaar M, Liao Z, Jansen PR, Andlauer TFM, Bates TC, Bernard M, Blokland K, Bonte M, Børglum AD, Bourgeron T, Brandeis D, Ceroni F, Csépe V, Dale PS, de Jong PF, DeFries JC, Démonet JF, Demontis D, Feng Y, Gordon SD, Guger SL, Hayiou-Thomas ME, Hernández-Cabrera JA, Hottenga JJ, Hulme C, Kere J, Kerr EN, Koomar T, Landerl K, Leonard GT, Lovett MW, Lyytinen H, Martin NG, Martinelli A, Maurer U, Michaelson JJ, Moll K, Monaco AP, Morgan AT, Nöthen MM, Pausova Z, Pennell CE, Pennington BF, Price KM, Rajagopal VM, Ramus F, Richer L, Simpson NH, Smith SD, Snowling MJ, Stein J, Strug LJ, Talcott JB, Tiemeier H, van der Schroeff MP, Verhoef E, Watkins KE, Wilkinson M, Wright MJ, Barr CL, Boomsma DI, Carreiras M, Franken MJ, Gruen JR, Luciano M, Müller-Myhsok B, Newbury DF, Olson RK, Paracchini S, Paus T, Plomin R, Reilly S, Schulte-Körne G, Tomblin JB, van Bergen E, Whitehouse AJO, Willcutt EG, St Pourcain B, Francks C, Fisher SE. Proc Natl Acad Sci U S A. 2022 Aug 30; 2022 Aug 23. PMID: 35998220.
• Dyslexia associated gene KIAA0319 regulates cell cycle during human neuroepithelial cell development.Paniagua S, Cakir B, Hu Y, Kiral FR, Tanaka Y, Xiang Y, Patterson B, Gruen JR, Park IH. Front Cell Dev Biol. 2022; 2022 Aug 9. PMID: 36016658.
• Orthographic Depth May Influence the Degree of Severity of Maze Learning Performance in Children at Risk for Reading Disorder.Gabel LA, Battison A, Truong DT, Lindström ER, Voss K, Yu YC, Roongruengratanakul S, Shyntassov K, Riebesell S, Toumanios N, Nielsen-Pheiffer CM, Paniagua S, Gruen JR. Dev Neurosci. 2022; 2022 Oct 12. PMID: 36223729.
• D-bifunctional protein deficiency caused by splicing variants in a neonate with severe peroxisomal dysfunction and persistent hypoglycemia.Werner KM, Cox AJ, Qian E, Jain P, Ji W, Tikhonova I, Castaldi C, Bilguvar K, Knight J, Ferdinandusse S, Fawaz R, Jiang YH, Gallagher PG, Bizzarro M, Gruen JR, Bale A, Zhang H. Am J Med Genet A. 2022 Jan; 2021 Oct 8. PMID: 34623748.
• Sex-specific associations between traumatic experiences and resting-state functional connectivity in the Philadelphia Neurodevelopmental Cohort.Wang S, Malins JG, Zhang H, Gruen JR. JCPP Adv. 2021 Dec; 2021 Dec 6. PMID: 34970657.
• Identifying Dyslexia: Link between Maze Learning and Dyslexia Susceptibility Gene, DCDC2, in Young Children.Gabel LA, Voss K, Johnson E, Lindström ER, Truong DT, Murray EM, Cariño K, Nielsen CM, Paniagua S, Gruen JR. Dev Neurosci. 2021; 2021 Jun 29. PMID: 34186533.
• The temporal dynamics of first and second language processing: ERPs to spoken words in Mandarin-English bilinguals.Xue J, Li B, Yan R, Gruen JR, Feng T, Joanisse MF, Malins JG. Neuropsychologia. 2020 Sep; 2020 Jul 17. PMID: 32682798.
• DCDC2 READ1 regulatory element: how temporal processing differences may shape language.Tang K, DeMille MMC, Frijters JC, Gruen JR. Proc Biol Sci. 2020 Jun 10; 2020 Jun 3. PMID: 32486976.
• Effect of READ1 on latent profiles of reading disorder and comorbid attention and language impairment subtypes.Li M, Truong DT, DeMille M, Malins JG, Lovett MW, Bosson-Heenan J, Gruen JR, Frijters JC. Child Neuropsychol. 2020 Feb; 2019 Aug 14. PMID: 31411106.
• Multivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth.Truong DT, Adams AK, Paniagua S, Frijters JC, Boada R, Hill DE, Lovett MW, Mahone EM, Willcutt EG, Wolf M, Defries JC, Gialluisi A, Francks C, Fisher SE, Olson RK, Pennington BF, Smith SD, Bosson-Heenan J, Gruen JR. J Med Genet. 2019 Aug; 2019 Apr 17. PMID: 30995994.
• Genetics of bronchopulmonary dysplasia: When things do not match up, it is only the beginning.Bhandari V, Gruen JR, Jang KL, Göpel W, Hallman M, Lavoie PM. J Pediatr. 2019 May; 2019 Feb 6. PMID: 30737034.
• Causal Attribution Profiles as a Function of Reading Skills, Hyperactivity, and Inattention.Tsujimoto KC, Boada R, Gottwald S, Hill D, Jacobson LA, Lovett M, Mahone EM, Willcutt E, Wolf M, Bosson-Heenan J, Gruen JR, Frijters JC. Sci Stud Read. 2019; 2018 Oct 22. PMID: 32523329.
• A molecular-genetic and imaging-genetic approach to specific comprehension difficulties in children.Li M, Malins JG, DeMille MMC, Lovett MW, Truong DT, Epstein K, Lacadie C, Mehta C, Bosson-Heenan J, Gruen JR, Frijters JC. NPJ Sci Learn. 2018; 2018 Nov 21. PMID: 30631481.
• Increased variability of stimulus-driven cortical responses is associated with genetic variability in children with and without dyslexia.Centanni TM, Pantazis D, Truong DT, Gruen JR, Gabrieli JDE, Hogan TP. Dev Cogn Neurosci. 2018 Nov; 2018 May 26. PMID: 29894888.
• Worldwide distribution of the DCDC2 READ1 regulatory element and its relationship with phoneme variation across languages.DeMille MMC, Tang K, Mehta CM, Geissler C, Malins JG, Powers NR, Bowen BM, Adams AK, Truong DT, Frijters JC, Gruen JR. Proc Natl Acad Sci U S A. 2018 May 8; 2018 Apr 16. PMID: 29666269.
• Achievement attributions are associated with specific rather than general learning delays.Tsujimoto KC, Frijters JC, Boada R, Gottwald S, Hill D, Jacobson LA, Lovett MW, Mahone EM, Willcutt EG, Wolf M, Bosson-Heenan J, Gruen JR. Learn Individ Differ. 2018 May; 2018 Apr 19. PMID: 32523322.
• Reading-Related Causal Attributions for Success and Failure: Dynamic Links With Reading Skill.Frijters JC, Tsujimoto KC, Boada R, Gottwald S, Hill D, Jacobson LA, Lovett MW, Mahone EM, Willcutt EG, Wolf M, Bosson-Heenan J, Gruen JR. Read Res Q. 2018 Jan-Mar; 2017 Apr 29. PMID: 29391653.
• Enrichment of putatively damaging rare variants in the DYX2 locus and the reading-related genes CCDC136 and FLNC.Adams AK, Smith SD, Truong DT, Willcutt EG, Olson RK, DeFries JC, Pennington BF, Gruen JR. Hum Genet. 2017 Nov; 2017 Sep 2. PMID: 28866788.
• Executive Functions Contribute Uniquely to Reading Competence in Minority Youth.Jacobson LA, Koriakin T, Lipkin P, Boada R, Frijters JC, Lovett MW, Hill D, Willcutt E, Gottwald S, Wolf M, Bosson-Heenan J, Gruen JR, Mahone EM. J Learn Disabil. 2017 Jul/Aug; 2016 Jan 11. PMID: 26755569.
• A method for integrating neuroimaging into genetic models of learning performance.Mehta CM, Gruen JR, Zhang H. Genet Epidemiol. 2017 Jan; 2016 Nov 18. PMID: 27859682.
• Multipoint genome-wide linkage scan for nonword repetition in a multigenerational family further supports chromosome 13q as a locus for verbal trait disorders.Truong DT, Shriberg LD, Smith SD, Chapman KL, Scheer-Cohen AR, DeMille MM, Adams AK, Nato AQ, Wijsman EM, Eicher JD, Gruen JR. Hum Genet. 2016 Dec; 2016 Aug 17. PMID: 27535846.
• Anxiety is related to indices of cortical maturation in typically developing children and adolescents.Newman E, Thompson WK, Bartsch H, Hagler DJ Jr, Chen CH, Brown TT, Kuperman JM, McCabe C, Chung Y, Libiger O, Akshoomoff N, Bloss CS, Casey BJ, Chang L, Ernst TM, Frazier JA, Gruen JR, Kennedy DN, Murray SS, Sowell ER, Schork N, Kenet T, Kaufmann WE, Mostofsky S, Amaral DG, Dale AM, Jernigan TL. Brain Struct Funct. 2016 Jul; 2015 Jul 17. PMID: 26183468.
• The regulatory element READ1 epistatically influences reading and language, with both deleterious and protective alleles.Powers NR, Eicher JD, Miller LL, Kong Y, Smith SD, Pennington BF, Willcutt EG, Olson RK, Ring SM, Gruen JR. J Med Genet. 2016 Mar; 2015 Dec 11. PMID: 26660103.
• Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children.Eicher JD, Montgomery AM, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork NJ, Darst BF, Casey BJ, Chang L, Ernst T, Frazier J, Kaufmann WE, Keating B, Kenet T, Kennedy D, Mostofsky S, Murray SS, Sowell ER, Bartsch H, Kuperman JM, Brown TT, Hagler DJ Jr, Dale AM, Jernigan TL, Gruen JR. Brain Imaging Behav. 2016 Mar. PMID: 25953057.
• The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository.Jernigan TL, Brown TT, Hagler DJ Jr, Akshoomoff N, Bartsch H, Newman E, Thompson WK, Bloss CS, Murray SS, Schork N, Kennedy DN, Kuperman JM, McCabe C, Chung Y, Libiger O, Maddox M, Casey BJ, Chang L, Ernst TM, Frazier JA, Gruen JR, Sowell ER, Kenet T, Kaufmann WE, Mostofsky S, Amaral DG, Dale AM. Neuroimage. 2016 Jan 1; 2015 May 1. PMID: 25937488.
• What is the basis for a genetic approach in neonatal disorders?Bhandari V, Gruen JR. Semin Perinatol. 2015 Dec; 2015 Oct 23. PMID: 26471062.
• Family income, parental education and brain structure in children and adolescents.Noble KG, Houston SM, Brito NH, Bartsch H, Kan E, Kuperman JM, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork NJ, Murray SS, Casey BJ, Chang L, Ernst TM, Frazier JA, Gruen JR, Kennedy DN, Van Zijl P, Mostofsky S, Kaufmann WE, Kenet T, Dale AM, Jernigan TL, Sowell ER. Nat Neurosci. 2015 May; 2015 Mar 30. PMID: 25821911.
• The DYX2 locus and neurochemical signaling genes contribute to speech sound disorder and related neurocognitive domains.Eicher JD, Stein CM, Deng F, Ciesla AA, Powers NR, Boada R, Smith SD, Pennington BF, Iyengar SK, Lewis BA, Gruen JR. Genes Brain Behav. 2015 Apr; 2015 Apr 8. PMID: 25778907.
• Language impairment and dyslexia genes influence language skills in children with autism spectrum disorders.Eicher JD, Gruen JR. Autism Res. 2015 Apr; 2014 Dec 1. PMID: 25448322.
• The DCDC2/intron 2 deletion and white matter disorganization: focus on developmental dyslexia.Marino C, Scifo P, Della Rosa PA, Mascheretti S, Facoetti A, Lorusso ML, Giorda R, Consonni M, Falini A, Molteni M, Gruen JR, Perani D. Cortex. 2014 Aug; 2014 May 9. PMID: 24926531.
• Characterization of the DYX2 locus on chromosome 6p22 with reading disability, language impairment, and IQ.Eicher JD, Powers NR, Miller LL, Mueller KL, Mascheretti S, Marino C, Willcutt EG, DeFries JC, Olson RK, Smith SD, Pennington BF, Tomblin JB, Ring SM, Gruen JR. Hum Genet. 2014 Jul; 2014 Feb 9. PMID: 24509779.
• The NIH Toolbox Cognition Battery: results from a large normative developmental sample (PING).Akshoomoff N, Newman E, Thompson WK, McCabe C, Bloss CS, Chang L, Amaral DG, Casey BJ, Ernst TM, Frazier JA, Gruen JR, Kaufmann WE, Kenet T, Kennedy DN, Libiger O, Mostofsky S, Murray SS, Sowell ER, Schork N, Dale AM, Jernigan TL. Neuropsychology. 2014 Jan; 2013 Nov 11. PMID: 24219608.
• Genome-wide association study of shared components of reading disability and language impairment.Eicher JD, Powers NR, Miller LL, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork NJ, Darst BF, Casey BJ, Chang L, Ernst T, Frazier J, Kaufmann WE, Keating B, Kenet T, Kennedy D, Mostofsky S, Murray SS, Sowell ER, Bartsch H, Kuperman JM, Brown TT, Hagler DJ Jr, Dale AM, Jernigan TL, St Pourcain B, Davey Smith G, Ring SM, Gruen JR. Genes Brain Behav. 2013 Nov; 2013 Oct 9. PMID: 24024963.
• Imaging-genetics in dyslexia: connecting risk genetic variants to brain neuroimaging and ultimately to reading impairments.Eicher JD, Gruen JR. Mol Genet Metab. 2013 Nov; 2013 Jul 17. PMID: 23916419.
• Alleles of a polymorphic ETV6 binding site in DCDC2 confer risk of reading and language impairment.Powers NR, Eicher JD, Butter F, Kong Y, Miller LL, Ring SM, Mann M, Gruen JR. Am J Hum Genet. 2013 Jul 11; 2013 Jun 6. PMID: 23746548.
• Associations of prenatal nicotine exposure and the dopamine related genes ANKK1 and DRD2 to verbal language.Eicher JD, Powers NR, Cho K, Miller LL, Mueller KL, Ring SM, Tomblin JB, Gruen JR. PLoS One. 2013; 2013 May 15. PMID: 23691092.
• Prenatal exposure to nicotine and impaired reading performance.Cho K, Frijters JC, Zhang H, Miller LL, Gruen JR. J Pediatr. 2013 Apr; 2012 Nov 2. PMID: 23122624.
• Variants in the DYX2 locus are associated with altered brain activation in reading-related brain regions in subjects with reading disability.Cope N, Eicher JD, Meng H, Gibson CJ, Hager K, Lacadie C, Fulbright RK, Constable RT, Page GP, Gruen JR. Neuroimage. 2012 Oct 15; 2012 Jun 27. PMID: 22750057.
• A highly sensitive, high-throughput assay for the detection of Turner syndrome.Rivkees SA, Hager K, Hosono S, Wise A, Li P, Rinder HM, Gruen JR. J Clin Endocrinol Metab. 2011 Mar; 2010 Dec 22. PMID: 21177792.
• The impact of environmental and genetic factors on neonatal late-onset sepsis.Bizzarro MJ, Jiang Y, Hussain N, Gruen JR, Bhandari V, Zhang H. J Pediatr. 2011 Feb; 2010 Sep 17. PMID: 20850766.
• A dyslexia-associated variant in DCDC2 changes gene expression.Meng H, Powers NR, Tang L, Cope NA, Zhang PX, Fuleihan R, Gibson C, Page GP, Gruen JR. Behav Genet. 2011 Jan; 2010 Nov 2. PMID: 21042874.
• Functional impact of a single-nucleotide polymorphism in the OPRD1 promoter region.Zhang H, Gelernter J, Gruen JR, Kranzler HR, Herman AI, Simen AA. J Hum Genet. 2010 May; 2010 Mar 19. PMID: 20300121.
• The genetic susceptibility to respiratory distress syndrome.Levit O, Jiang Y, Bizzarro MJ, Hussain N, Buhimschi CS, Gruen JR, Zhang H, Bhandari V. Pediatr Res. 2009 Dec. PMID: 19687775.
• Cognitive flexibility is associated with KIBRA variant and modulated by recent tobacco use.Zhang H, Kranzler HR, Poling J, Gruen JR, Gelernter J. Neuropsychopharmacology. 2009 Nov; 2009 Jul 15. PMID: 19606085.
• Genetic contribution to patent ductus arteriosus in the premature newborn.Bhandari V, Zhou G, Bizzarro MJ, Buhimschi C, Hussain N, Gruen JR, Zhang H. Pediatrics. 2009 Feb. PMID: 19171636.
• Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence.Yang BZ, Kranzler HR, Zhao H, Gruen JR, Luo X, Gelernter J. Alcohol Clin Exp Res. 2008 Dec; 2008 Sep 30. PMID: 18828801.
• The human lexinome: genes of language and reading.Gibson CJ, Gruen JR. J Commun Disord. 2008 Sep-Oct; 2008 Mar 25. PMID: 18466916.
• Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples.Yang BZ, Kranzler HR, Zhao H, Gruen JR, Luo X, Gelernter J. Hum Mol Genet. 2007 Dec 1; 2007 Aug 30. PMID: 17761687.
• Management of dyslexia, its rationale, and underlying neurobiology.Shaywitz SE, Gruen JR, Shaywitz BA. Pediatr Clin North Am. 2007 Jun. PMID: 17543912.
• Guideline for data analysis of genomewide association studies.Zhang H, Liu L, Wang X, Gruen JR. Cancer Genomics Proteomics. 2007 Jan-Feb. PMID: 17726238.
• Genetic approaches to complications of prematurity.Meng H, Gruen JR. Front Biosci. 2007 Jan 1; 2007 Jan 1. PMID: 17127244.
• Genetic susceptibility to retinopathy of prematurity.Bizzarro MJ, Hussain N, Jonsson B, Feng R, Ment LR, Gruen JR, Zhang H, Bhandari V. Pediatrics. 2006 Nov. PMID: 17079555.
• The genetics of bronchopulmonary dysplasia.Bhandari V, Gruen JR. Semin Perinatol. 2006 Aug. PMID: 16860158.
• Familial and genetic susceptibility to major neonatal morbidities in preterm twins.Bhandari V, Bizzarro MJ, Shetty A, Zhong X, Page GP, Zhang H, Ment LR, Gruen JR. Pediatrics. 2006 Jun. PMID: 16740829.
• DCDC2 is associated with reading disability and modulates neuronal development in the brain.Meng H, Smith SD, Hager K, Held M, Liu J, Olson RK, Pennington BF, DeFries JC, Gelernter J, O'Reilly-Pol T, Somlo S, Skudlarski P, Shaywitz SE, Shaywitz BA, Marchione K, Wang Y, Paramasivam M, LoTurco JJ, Page GP, Gruen JR. Proc Natl Acad Sci U S A. 2005 Nov 22; 2005 Nov 8. PMID: 16278297.
• TDT-association analysis of EKN1 and dyslexia in a Colorado twin cohort.Meng H, Hager K, Held M, Page GP, Olson RK, Pennington BF, DeFries JC, Smith SD, Gruen JR. Hum Genet. 2005 Oct; 2005 Oct 28. PMID: 16133186.
• Detection of Turner syndrome using high-throughput quantitative genotyping.Meng H, Hager K, Rivkees SA, Gruen JR. J Clin Endocrinol Metab. 2005 Jun; 2005 Mar 29. PMID: 15797949.
• Evidence for linkage and association with reading disability on 6p21.3-22.Kaplan DE, Gayán J, Ahn J, Won TW, Pauls D, Olson RK, DeFries JC, Wood F, Pennington BF, Page GP, Smith SD, Gruen JR. Am J Hum Genet. 2002 May; 2002 Apr 10. PMID: 11951179.
• Human MHC class III and IV genes and disease associations.Gruen JR, Weissman SM. Front Biosci. 2001 Aug 1; 2001 Aug 1. PMID: 11487469.
• Human GABA(B) receptor 1 gene: eight novel sequence variants.Hisama FM, Gruen JR, Choi J, Huseinovic M, Grigorenko EL, Pauls D, Mattson RH, Gelernter J, Wood FB, Goei VL. Hum Mutat. 2001 Apr. PMID: 11295833.
• Genetics of childhood disorders: VII. Cloning genes of interest.Sparks R, Lombroso PJ, Gruen JR. J Am Acad Child Adolesc Psychiatry. 1999 Oct. PMID: 10517067.
• The genomic organization of the histone clusters on human 6p21.3.Ahn J, Gruen JR. Mamm Genome. 1999 Jul. PMID: 10384058.
• Human gamma-aminobutyric acid B receptor gene: complementary DNA cloning, expression, chromosomal location, and genomic organization.Goei VL, Choi J, Ahn J, Bowlus CL, Raha-Chowdhury R, Gruen JR. Biol Psychiatry. 1998 Oct 15. PMID: 9798068.
• Evolving views of the major histocompatibility complex.Gruen JR, Weissman SM. Blood. 1997 Dec 1. PMID: 9373235.
• FISH-Mapped CEPH YACs spanning 0 to 46 cM on human chromosome 6.Bray-Ward P, Bowlus C, Choi J, Paslier DL, Weissenbach J, Gruen JR. Genomics. 1996 Aug 15. PMID: 8812421.
• A transcription map of the major histocompatibility complex (MHC) class I region.Gruen JR, Nalabolu SR, Chu TW, Bowlus C, Fan WF, Goei VL, Wei H, Sivakamasundari R, Liu Y, Xu HX, Parimoo S, Nallur G, Ajioka R, Shukla H, Bray-Ward P, Pan J, Weissman SM. Genomics. 1996 Aug 15. PMID: 8812418.
• Cloning of a new "finger" protein gene (ZNF173) within the class I region of the human MHC.Chu TW, Capossela A, Coleman R, Goei VL, Nallur G, Gruen JR. Genomics. 1995 Sep 1. PMID: 8530076.
• Isolation of novel non-HLA gene fragments from the hemochromatosis region (6p21.3) by cDNA hybridization selection.Goei VL, Parimoo S, Capossela A, Chu TW, Gruen JR. Am J Hum Genet. 1994 Feb. PMID: 8304341.
• Physical and genetic mapping of the telomeric major histocompatibility complex region in man and relevance to the primary hemochromatosis gene (HFE).Gruen JR, Goei VL, Summers KM, Capossela A, Powell L, Halliday J, Zoghbi H, Shukla H, Weissman SM. Genomics. 1992 Oct. PMID: 1427838.