Journal Club

The broadly conserved regulator PhoP links pathogen virulence and membrane potential in Escherichia coli.

Alteri CJ, Lindner JR, Reiss DJ, Smith SN, Mobley HL.

Transfer-messenger RNA controls the translation of cell-cycle and stress proteins in Streptomyces.

Barends S, Zehl M, Bialek S, de Waal E, Traag BA, Willemse J, Jensen ON, Vijgenboom E, van Wezel GP.

Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D.

Chaigne-Delalande B et al.

Sequential evolution of bacterial morphology by co-option of a developmental regulator.

Jiang C et al.

Trade-off between bile resistance and nutritional competence drives Escherichia coli diversification in the mouse gut.

De Paepe M, Gaboriau-Routhiau V, Rainteau D, Rakotobe S, Taddei F, Cerf-Bensussan N.

A three-protein signaling pathway governing immunity to a bacterial cannibalism toxin.

Ellermeier CD, Hobbs EC, Gonzalez-Pastor JE, Losick R.

A general O-glycosylation system important to the physiology of a major human intestinal symbiont.

Fletcher CM et al.

Direct interaction between sensor kinase proteins mediates acute and chronic disease phenotypes in a bacterial pathogen.

Goodman AL, Merighi M, Hyodo M, Ventre I, Filloux A, Lory S.

Remodelling of the Escherichia coli outer membrane by two small regulatory RNAs.

Guillier M, Gottesman S.

Internalization of Salmonella by macrophages induces formation of nonreplicating persisters.

Helaine S et al.

Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling.

Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS.

Regulated virulence controls the ability of a pathogen to compete with the gut microbiota.

Kamada N, Kim YG, Sham HP, Vallance BA, Puente JL, Martens EC, Núñez G.

Functioning of a metabolic flux sensor in Escherichia coli.

Kochanowski K, Volkmer B, Gerosa L, R Haverkorn van Rijsewijk B, Schmidt A, Heinemann M.

Bacterial evolution of antibiotic hypersensitivity.

Lazar V et al.

The competitive advantage of a dual-transporter system.

Levy S, Kafri M, Carmi M, Barkai N.

The anti-Shine-Dalgarno sequence drives translational pausing and codon choice in bacteria.

Li GW, Oh E, Weissman JS.

A riboswitch-regulated antisense RNA in Listeria monocytogenes.

Mellin JR, Tiensuu T, Bécavin C, Gouin E, Johansson J, Cossart P.

Yersinia pestis genome sequencing identifies patterns of global phylogenetic diversity.

Morelli G et al.

Phenotypic landscape of a bacterial cell.

Nichols RJ et al.

Cytoplasmic ATP hydrolysis powers transport of lipopolysaccharide across the periplasm in E. coli.

Okuda S, Freinkman E, Kahne D.

Interplay of transcriptional and small RNA-dependent control mechanisms regulates chitosugar uptake in Escherichia coli and Salmonella.

Plumbridge J et al.

Secreted transcription factor controls Mycobacterium tuberculosis virulence.

Raghavan S, Manzanillo P, Chan K, Dovey C, Cox JS.

The ABC transporter MalFGK2 sequesters the MalT transcription factor at the membrane in the absence of cognate substrate.

Richet E, Davidson AL, Joly N.

Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo.

Rouskin S et al.

Local absence of secondary structure permits translation of mRNAs that lack ribosome-binding sites.

Scharff LB, Childs L, Walther D, Bock R.

Microanatomy at cellular resolution and spatial order of physiological differentiation in a bacterial biofilm.

Serra DO, Richter AM, Klauck G, Mika F, Hengge R.

Bet-hedging during bacterial diauxic shift.

Solopova A et al.

Environmental perturbations lift the degeneracy of the genetic code to regulate protein levels in bacteria. 

Subramaniam AR, Pan T, Cluzel P.

Oligonucleotide recombination in Gram-negative bacteria.

Swingle B, Markel E, Costantino N, Bubunenko MG, Cartinhour S, Court DL.

YycH regulates the activity of the essential YycFG two-component system in Bacillus subtilis.

Szurmant H, Nelson K, Kim EJ, Perego M, Hoch JA.

Structure and mechanisms of a protein-based organelle in Escherichia coli.

Tanaka S, Sawaya MR, Yeates TO.

Two variable active site residues modulate response regulator phosphoryl group stability.

Thomas SA, Brewster JA, Bourret RB.

Sensing wetness: a new role for the bacterial flagellum.

Wang Q, Suzuki A, Mariconda S, Porwollik S, Harshey RM.

The ydaO motif is an ATP-sensing riboswitch in Bacillus subtilis.

Watson PY, Fedor MJ.

Regulation of yeast pyruvate kinase by ultrasensitive allostery independent of phosphorylation.

Xu YF, Zhao X, Glass DS, Absalan F, Perlman DH, Broach JR, Rabinowitz JD.

pH sensing by intracellular Salmonella induces effector translocation.

Yu XJ, McGourty K, Liu M, Unsworth KE, Holden DW.

Conformational control of the Ste5 scaffold protein insulates against MAP kinase misactivation.

Zalatan JG, Coyle SM, Rajan S, Sidhu SS, Lim WA.

Sequential checkpoints govern substrate selection during cotranslational protein targeting.

Zhang X, Rashid R, Wang K, Shan SO.

Mg2+ facilitates leader peptide translation to induce riboswitch-mediated transcription termination.

Zhao G, Kong W, Weatherspoon-Griffin N, Clark-Curtiss J, Shi Y.