Welcome to Greif Lab

My laboratory investigates blood vessel morphogenesis, the maintenance of the adult blood vessel and diseases of the vasculature. To this end, we utilize fundamental biochemical, state-of-the-art genetic and developmental biological approaches.


Current Projects:

  • Aortic wall development and disease: specification, migration and differentiation.
  • Mural cell TGFβ signaling and blood brain barrier formation: implication for intracerebral hemorrhage.
  • Excess smooth muscle in pulmonary hypertension: cellular origins and recruitment and the role of pluripotency factors.