Publications
2024
- Intracellular calcium links milk stasis to lysosome-dependent cell death during early mammary gland involution.Jeong J, Lee J, Talaia G, Kim W, Song J, Hong J, Yoo K, Gonzalez DG, Athonvarangkul D, Shin J, Dann P, Haberman AM, Kim LK, Ferguson SM, Choi J, Wysolmerski J. Cell Mol Life Sci. 2024 Jan 12; 2024 Jan 12. PMID: 38212474.
2023
- Lysosomal TBK1 Responds to Amino Acid Availability to Relieve Rab7-Dependent mTORC1 Inhibition.Talaia G, Bentley-DeSousa A, Ferguson SM. bioRxiv. 2023 Dec 17; 2023 Dec 17. PMID: 38168426.
- A kinesin-1 adaptor complex controls bimodal slow axonal transport of spectrin in Caenorhabditis elegans.Glomb O, Swaim G, Munoz LLancao P, Lovejoy C, Sutradhar S, Park J, Wu Y, Cason SE, Holzbaur ELF, Hammarlund M, Howard J, Ferguson SM, Gramlich MW, Yogev S. Dev Cell. 2023 Oct 9; 2023 Sep 25. PMID: 37751746.
- LRRK2 suppresses lysosome degradative activity in macrophages and microglia through MiT-TFE transcription factor inhibition.Yadavalli N, Ferguson SM. Proc Natl Acad Sci U S A. 2023 Aug; 2023 Jul 24. PMID: 37487100.
- Cab45 deficiency leads to the mistargeting of progranulin and prosaposin and aberrant lysosomal positioning.Tran ML, Tüshaus J, Kim Y, Ramazanov BR, Devireddy S, Lichtenthaler SF, Ferguson SM, von Blume J. Traffic. 2023 Jan. PMID: 36398980.
2022
- ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling.Hancock-Cerutti W, Wu Z, Xu P, Yadavalli N, Leonzino M, Tharkeshwar AK, Ferguson SM, Shadel GS, De Camilli P. J Cell Biol. 2022 Jul 4; 2022 Jun 3. PMID: 35657605.
- Efficient progranulin exit from the ER requires its interaction with prosaposin, a Surf4 cargo.Devireddy S, Ferguson SM. J Cell Biol. 2022 Feb 7; 2021 Dec 17. PMID: 34919127.
- JIP3 links lysosome transport to regulation of multiple components of the axonal cytoskeleton.Rafiq NM, Lyons LL, Gowrishankar S, De Camilli P, Ferguson SM. Commun Biol. 2022 Jan 10; 2022 Jan 10. PMID: 35013510.
2021
- TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism.Alesi N, Akl EW, Khabibullin D, Liu HJ, Nidhiry AS, Garner ER, Filippakis H, Lam HC, Shi W, Viswanathan SR, Morroni M, Ferguson SM, Henske EP. Nat Commun. 2021 Jul 12; 2021 Jul 12. PMID: 34253722.
- Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons.Gowrishankar S, Lyons L, Rafiq NM, Roczniak-Ferguson A, De Camilli P, Ferguson SM. Mol Biol Cell. 2021 May 15; 2021 Mar 31. PMID: 33788575.