Publications

Zhang W, Xie M, Shu MD, Steitz JA, DiMaio D: A proximity-dependent assay for specific RNA-protein interactions in intact cells. RNA. 2016 Sep 22; 2016 Sep 22. PMID: 27659050

Gil da Costa RM, Peleteiro MC, Pires MA, DiMaio D: An Update on Canine, Feline and Bovine Papillomaviruses. Transbound Emerg Dis. 2016 Sep 11; 2016 Sep 11. PMID: 27615361

Coit DG, Thompson JA, Algazi A, Andtbacka R, Bichakjian CK, Carson WE 3rd, Daniels GA, DiMaio D, Fields RC, Fleming MD, Gastman B, Gonzalez R, Guild V, Johnson D, Joseph RW, Lange JR, Martini MC, Materin MA, Olszanski AJ, Ott P, Gupta AP, Ross MI, Salama AK, Skitzki J, Swetter SM, Tanabe KK, Torres-Roca JF, Trisal V, Urist MM, McMillian N, Engh A: NCCN Guidelines Insights: Melanoma, Version 3.2016. J Natl Compr Canc Netw. 2016 Aug. PMID: 27496110

Luo Y, Motamedi N, Magaldi TG, Gee GV, Atwood WJ, DiMaio D: Interaction between Simian Virus 40 Major Capsid Protein VP1 and Cell Surface Ganglioside GM1 Triggers Vacuole Formation. MBio. 2016 Mar 22; 2016 Mar 22. PMID: 27006465

DiMaio D: Thank You, Edward. Merci, Louis. PLoS Pathog. 2016 Jan; 2016 Jan 14. PMID: 26766042

Heim EN, Marston JL, Federman RS, Edwards AP, Karabadzhak AG, Petti LM, Engelman DM, DiMaio D: Biologically active LIL proteins built with minimal chemical diversity. Proc Natl Acad Sci U S A. 2015 Aug 25; 2015 Aug 10. PMID: 26261320

DiMaio D, Burd CG, Goodner K: Riding the R Train into the Cell. PLoS Pathog. 2015 Aug; 2015 Aug 20. PMID: 26291450

Xie M, Zhang W, Shu MD, Xu A, Lenis DA, DiMaio D, Steitz JA: The host Integrator complex acts in transcription-independent maturation of herpesvirus microRNA 3' ends. Genes Dev. 2015 Jul 15. PMID: 26220997

Ströh LJ, Maginnis MS, Blaum BS, Nelson CD, Neu U, Gee GV, O'Hara BA, Motamedi N, DiMaio D, Atwood WJ, Stehle T: The Greater Affinity of JC Polyomavirus Capsid for α2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J Virol. 2015 Jun; 2015 Apr 8. PMID: 25855729

DiMaio D: Nuns, warts, viruses, and cancer. Yale J Biol Med. 2015 Jun; 2015 Jun 1. PMID: 26029011

DiMaio D: Zombies in TCGA. J Virol. 2015 Apr; 2015 Jan 28. PMID: 25631081

Popa A, Zhang W, Harrison MS, Goodner K, Kazakov T, Goodwin EC, Lipovsky A, Burd CG, DiMaio D: Direct binding of retromer to human papillomavirus type 16 minor capsid protein L2 mediates endosome exit during viral infection. PLoS Pathog. 2015 Feb; 2015 Feb 18. PMID: 25693203

Lipovsky A, Zhang W, Iwasaki A, DiMaio D: Application of the proximity-dependent assay and fluorescence imaging approaches to study viral entry pathways. Methods Mol Biol. 2015. PMID: 25702134

Zhang W, Kazakov T, Popa A, DiMaio D: Vesicular trafficking of incoming human papillomavirus 16 to the Golgi apparatus and endoplasmic reticulum requires γ-secretase activity. MBio. 2014 Sep 16; 2014 Sep 16. PMID: 25227470

Carney DW, Nelson CD, Ferris BD, Stevens JP, Lipovsky A, Kazakov T, DiMaio D, Atwood WJ, Sello JK: Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma- and papillomaviruses. Bioorg Med Chem. 2014 Sep 1; 2014 Jul 10. PMID: 25087050

Dimaio D: Is virology dead? MBio. 2014 Mar 25; 2014 Mar 25. PMID: 24667711

Chacón KM, Petti LM, Scheideman EH, Pirazzoli V, Politi K, DiMaio D: De novo selection of oncogenes. Proc Natl Acad Sci U S A. 2014 Jan 7; 2013 Dec 16. PMID: 24344264

DiMaio D: Viral miniproteins. Annu Rev Microbiol. 2014; 2014 Apr 10. PMID: 24742054

Cohen EB, Jun SJ, Bears Z, Barrera FN, Alonso M, Engelman DM, DiMaio D: Mapping the homodimer interface of an optimized, artificial, transmembrane protein activator of the human erythropoietin receptor. PLoS One. 2014; 2014 Apr 30. PMID: 24788775

Goodwin EC, Motamedi N, Lipovsky A, Fernández-Busnadiego R, DiMaio D: Expression of DNAJB12 or DNAJB14 causes coordinate invasion of the nucleus by membranes associated with a novel nuclear pore structure. PLoS One. 2014; 2014 Apr 14. PMID: 24732912

Edwards AP, Xie Y, Bowers L, DiMaio D: Compensatory mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor β receptor reveal a complex direct transmembrane interaction. J Virol. 2013 Oct; 2013 Aug 7. PMID: 23926343

DiMaio D, Petti LM: The E5 proteins. Virology. 2013 Oct; 2013 May 31. PMID: 23731971

Petti LM, Talbert-Slagle K, Hochstrasser ML, DiMaio D: A single amino acid substitution converts a transmembrane protein activator of the platelet-derived growth factor β receptor into an inhibitor. J Biol Chem. 2013 Sep 20; 2013 Aug 1. PMID: 23908351

Iijima N, Goodwin EC, Dimaio D, Iwasaki A: High-risk human papillomavirus E6 inhibits monocyte differentiation to Langerhans cells. Virology. 2013 Sep; 2013 Jul 18. PMID: 23871219

Lipovsky A, Popa A, Pimienta G, Wyler M, Bhan A, Kuruvilla L, Guie MA, Poffenberger AC, Nelson CD, Atwood WJ, DiMaio D: Genome-wide siRNA screen identifies the retromer as a cellular entry factor for human papillomavirus. Proc Natl Acad Sci U S A. 2013 Apr 30; 2013 Apr 8. PMID: 23569269

Scheideman EH, Marlatt SA, Xie Y, Hu Y, Sutton RE, DiMaio D: Transmembrane protein aptamers that inhibit CCR5 expression and HIV coreceptor function. J Virol. 2012 Oct; 2012 Jul 18. PMID: 22811524

Magaldi TG, Buch MH, Murata H, Erickson KD, Neu U, Garcea RL, Peden K, Stehle T, DiMaio D: Mutations in the GM1 binding site of simian virus 40 VP1 alter receptor usage and cell tropism. J Virol. 2012 Jul; 2012 Apr 18. PMID: 22514351

DiMaio D: Viruses, masters at downsizing. Cell Host Microbe. 2012 Jun 14. PMID: 22704616

Magaldi TG, Almstead LL, Bellone S, Prevatt EG, Santin AD, DiMaio D: Primary human cervical carcinoma cells require human papillomavirus E6 and E7 expression for ongoing proliferation. Virology. 2012 Jan 5; 2011 Nov 5. PMID: 22056390

Martinez I, Dimaio D: B-Myb, cancer, senescence, and microRNAs. Cancer Res. 2011 Aug 15; 2011 Aug 9. PMID: 21828240

Goodwin EC, Lipovsky A, Inoue T, Magaldi TG, Edwards AP, Van Goor KE, Paton AW, Paton JC, Atwood WJ, Tsai B, DiMaio D: BiP and multiple DNAJ molecular chaperones in the endoplasmic reticulum are required for efficient simian virus 40 infection. MBio. 2011; 2011 Jun 14. PMID: 21673190

Marlatt SA, Kong Y, Cammett TJ, Korbel G, Noonan JP, Dimaio D: Construction and maintenance of randomized retroviral expression libraries for transmembrane protein engineering. Protein Eng Des Sel. 2011 Mar; 2010 Dec 10. PMID: 21149273

Martinez I, Almstead LL, DiMaio D: MicroRNAs and senescence. Aging (Albany NY). 2011 Feb. PMID: 21304181

Martinez I, Cazalla D, Almstead LL, Steitz JA, DiMaio D: miR-29 and miR-30 regulate B-Myb expression during cellular senescence. Proc Natl Acad Sci U S A. 2011 Jan 11; 2010 Dec 27. PMID: 21187425

Cammett TJ, Jun SJ, Cohen EB, Barrera FN, Engelman DM, Dimaio D: Construction and genetic selection of small transmembrane proteins that activate the human erythropoietin receptor. Proc Natl Acad Sci U S A. 2010 Feb 23; 2010 Feb 8. PMID: 20142506

Talbert-Slagle K, Marlatt S, Barrera FN, Khurana E, Oates J, Gerstein M, Engelman DM, Dixon AM, Dimaio D: Artificial transmembrane oncoproteins smaller than the bovine papillomavirus E5 protein redefine sequence requirements for activation of the platelet-derived growth factor beta receptor. J Virol. 2009 Oct; 2009 Jul 15. PMID: 19605488

Goodwin EC, Atwood WJ, DiMaio D: High-throughput cell-based screen for chemicals that inhibit infection by simian virus 40 and human polyomaviruses. J Virol. 2009 Jun; 2009 Mar 18. PMID: 19297472

Talbert-Slagle K, DiMaio D: The bovine papillomavirus E5 protein and the PDGF beta receptor: it takes two to tango. Virology. 2009 Feb 20; 2008 Nov 6. PMID: 18990418

Yates KE, Korbel GA, Shtutman M, Roninson IB, DiMaio D: Repression of the SUMO-specific protease Senp1 induces p53-dependent premature senescence in normal human fibroblasts. Aging Cell. 2008 Oct; 2008 Jul 24. PMID: 18616636

Liao JB, Publicover J, Rose JK, DiMaio D: Single-dose, therapeutic vaccination of mice with vesicular stomatitis virus expressing human papillomavirus type 16 E7 protein. Clin Vaccine Immunol. 2008 May; 2008 Mar 12. PMID: 18337377

Psyrri A, DiMaio D: Human papillomavirus in cervical and head-and-neck cancer. Nat Clin Pract Oncol. 2008 Jan. PMID: 18097454

DiMaio D, Miller G: Thirty years into the genomics era: tumor viruses led the way. Yale J Biol Med. 2006 Dec. PMID: 17940630

Lee BY, Han JA, Im JS, Morrone A, Johung K, Goodwin EC, Kleijer WJ, DiMaio D, Hwang ES: Senescence-associated beta-galactosidase is lysosomal beta-galactosidase. Aging Cell. 2006 Apr. PMID: 16626397

Sweasy JB, Lang T, DiMaio D: Is base excision repair a tumor suppressor mechanism? Cell Cycle. 2006 Feb; 2006 Feb 14. PMID: 16418580

DiMaio D, Liao JB: Human papillomaviruses and cervical cancer. Adv Virus Res. 2006. PMID: 16877060

Freeman-Cook LL, Dimaio D: Modulation of cell function by small transmembrane proteins modeled on the bovine papillomavirus E5 protein. Oncogene. 2005 Nov 21. PMID: 16299535

Sweasy JB, Lang T, Starcevic D, Sun KW, Lai CC, Dimaio D, Dalal S: Expression of DNA polymerase {beta} cancer-associated variants in mouse cells results in cellular transformation. Proc Natl Acad Sci U S A. 2005 Oct 4; 2005 Sep 22. PMID: 16179390

Lai CC, Edwards AP, DiMaio D: Productive interaction between transmembrane mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor beta receptor. J Virol. 2005 Feb. PMID: 15650217

Freeman-Cook LL, Edwards AP, Dixon AM, Yates KE, Ely L, Engelman DM, Dimaio D: Specific locations of hydrophilic amino acids in constructed transmembrane ligands of the platelet-derived growth factor beta receptor. J Mol Biol. 2005 Jan 28. PMID: 15588835

Freeman-Cook LL, Dixon AM, Frank JB, Xia Y, Ely L, Gerstein M, Engelman DM, DiMaio D: Selection and characterization of small random transmembrane proteins that bind and activate the platelet-derived growth factor beta receptor. J Mol Biol. 2004 May 14. PMID: 15111056

Psyrri A, DeFilippis RA, Edwards AP, Yates KE, Manuelidis L, DiMaio D: Role of the retinoblastoma pathway in senescence triggered by repression of the human papillomavirus E7 protein in cervical carcinoma cells. Cancer Res. 2004 May 1. PMID: 15126344

Horner SM, DeFilippis RA, Manuelidis L, DiMaio D: Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells. J Virol. 2004 Apr. PMID: 15047823

Irusta PM, Luo Y, Bakht O, Lai CC, Smith SO, DiMaio D: Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor. J Biol Chem. 2002 Oct 11; 2002 Aug 13. PMID: 12181311

DiMaio D, Mattoon D: Mechanisms of cell transformation by papillomavirus E5 proteins. Oncogene. 2001 Nov 26. PMID: 11753669

Goodwin EC, DiMaio D: Induced senescence in HeLa cervical carcinoma cells containing elevated telomerase activity and extended telomeres. Cell Growth Differ. 2001 Nov. PMID: 11714633

Mattoon D, Gupta K, Doyon J, Loll PJ, DiMaio D: Identification of the transmembrane dimer interface of the bovine papillomavirus E5 protein. Oncogene. 2001 Jun 28. PMID: 11439346

DiMaio D, Lai CC, Mattoon D: The platelet-derived growth factor beta receptor as a target of the bovine papillomavirus E5 protein. Cytokine Growth Factor Rev. 2000 Dec. PMID: 10959076

Goodwin EC, DiMaio D: Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways. Proc Natl Acad Sci U S A. 2000 Nov 7. PMID: 11070078

Wu L, Goodwin EC, Naeger LK, Vigo E, Galaktionov K, Helin K, DiMaio D: E2F-Rb complexes assemble and inhibit cdc25A transcription in cervical carcinoma cells following repression of human papillomavirus oncogene expression. Mol Cell Biol. 2000 Oct. PMID: 10982822

Goodwin EC, Yang E, Lee CJ, Lee HW, DiMaio D, Hwang ES: Rapid induction of senescence in human cervical carcinoma cells. Proc Natl Acad Sci U S A. 2000 Sep 26. PMID: 11005870

Lai CC, Henningson C, DiMaio D: Bovine papillomavirus E5 protein induces the formation of signal transduction complexes containing dimeric activated platelet-derived growth factor beta receptor and associated signaling proteins. J Biol Chem. 2000 Mar 31. PMID: 10734138

Drummond-Barbosa D, DiMaio D: Virocrine transformation. Biochim Biophys Acta. 1997 Feb 22. PMID: 9061007

Hwang ES, Naeger LK, DiMaio D: Activation of the endogenous p53 growth inhibitory pathway in HeLa cervical carcinoma cells by expression of the bovine papillomavirus E2 gene. Oncogene. 1996 Feb 15. PMID: 8632901

Kegler-Ebo DM, Polack GW, DiMaio D: Use of codon cassette mutagenesis for saturation mutagenesis. Methods Mol Biol. 1996. PMID: 8850016