Publications

Xie M, Zhang W, Shu MD, Xu A, Lenis DA, DiMaio D, Steitz JA: The host Integrator complex acts in transcription-independent maturation of herpesvirus microRNA 3' ends. Genes Dev. 2015 Jul 15. PMID: 26220997

Ströh LJ, Maginnis MS, Blaum BS, Nelson CD, Neu U, Gee GV, O'Hara BA, Motamedi N, DiMaio D, Atwood WJ, Stehle T: The Greater Affinity of JC Polyomavirus Capsid for α2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J Virol. 2015 Jun; 2015 Apr 8. PMID: 25855729

DiMaio D: Nuns, warts, viruses, and cancer. Yale J Biol Med. 2015 Jun; 2015 Jun 1. PMID: 26029011

DiMaio D: Zombies in TCGA. J Virol. 2015 Apr; 2015 Jan 28. PMID: 25631081

Popa A, Zhang W, Harrison MS, Goodner K, Kazakov T, Goodwin EC, Lipovsky A, Burd CG, DiMaio D: Direct binding of retromer to human papillomavirus type 16 minor capsid protein L2 mediates endosome exit during viral infection. PLoS Pathog. 2015 Feb; 2015 Feb 18. PMID: 25693203

Lipovsky A, Zhang W, Iwasaki A, DiMaio D: Application of the proximity-dependent assay and fluorescence imaging approaches to study viral entry pathways. Methods Mol Biol. 2015. PMID: 25702134

Zhang W, Kazakov T, Popa A, DiMaio D: Vesicular trafficking of incoming human papillomavirus 16 to the Golgi apparatus and endoplasmic reticulum requires γ-secretase activity. MBio. 2014 Sep 16; 2014 Sep 16. PMID: 25227470

Carney DW, Nelson CD, Ferris BD, Stevens JP, Lipovsky A, Kazakov T, DiMaio D, Atwood WJ, Sello JK: Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma- and papillomaviruses. Bioorg Med Chem. 2014 Sep 1; 2014 Jul 10. PMID: 25087050

Dimaio D: Is virology dead? MBio. 2014 Mar 25; 2014 Mar 25. PMID: 24667711

Chacón KM, Petti LM, Scheideman EH, Pirazzoli V, Politi K, DiMaio D: De novo selection of oncogenes. Proc Natl Acad Sci U S A. 2014 Jan 7; 2013 Dec 16. PMID: 24344264

DiMaio D: Viral miniproteins. Annu Rev Microbiol. 2014; 2014 Apr 10. PMID: 24742054

Cohen EB, Jun SJ, Bears Z, Barrera FN, Alonso M, Engelman DM, DiMaio D: Mapping the homodimer interface of an optimized, artificial, transmembrane protein activator of the human erythropoietin receptor. PLoS One. 2014; 2014 Apr 30. PMID: 24788775

Goodwin EC, Motamedi N, Lipovsky A, Fernández-Busnadiego R, DiMaio D: Expression of DNAJB12 or DNAJB14 causes coordinate invasion of the nucleus by membranes associated with a novel nuclear pore structure. PLoS One. 2014; 2014 Apr 14. PMID: 24732912

Edwards AP, Xie Y, Bowers L, DiMaio D: Compensatory mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor β receptor reveal a complex direct transmembrane interaction. J Virol. 2013 Oct; 2013 Aug 7. PMID: 23926343

DiMaio D, Petti LM: The E5 proteins. Virology. 2013 Oct; 2013 May 31. PMID: 23731971

Iijima N, Goodwin EC, Dimaio D, Iwasaki A: High-risk human papillomavirus E6 inhibits monocyte differentiation to Langerhans cells. Virology. 2013 Sep; 2013 Jul 18. PMID: 23871219

Lipovsky A, Popa A, Pimienta G, Wyler M, Bhan A, Kuruvilla L, Guie MA, Poffenberger AC, Nelson CD, Atwood WJ, DiMaio D: Genome-wide siRNA screen identifies the retromer as a cellular entry factor for human papillomavirus. Proc Natl Acad Sci U S A. 2013 Apr 30; 2013 Apr 8. PMID: 23569269

Scheideman EH, Marlatt SA, Xie Y, Hu Y, Sutton RE, DiMaio D: Transmembrane protein aptamers that inhibit CCR5 expression and HIV coreceptor function. J Virol. 2012 Oct; 2012 Jul 18. PMID: 22811524

Magaldi TG, Buch MH, Murata H, Erickson KD, Neu U, Garcea RL, Peden K, Stehle T, DiMaio D: Mutations in the GM1 binding site of simian virus 40 VP1 alter receptor usage and cell tropism. J Virol. 2012 Jul; 2012 Apr 18. PMID: 22514351

DiMaio D: Viruses, masters at downsizing. Cell Host Microbe. 2012 Jun 14. PMID: 22704616

Magaldi TG, Almstead LL, Bellone S, Prevatt EG, Santin AD, DiMaio D: Primary human cervical carcinoma cells require human papillomavirus E6 and E7 expression for ongoing proliferation. Virology. 2012 Jan 5; 2011 Nov 5. PMID: 22056390

Martinez I, Dimaio D: B-Myb, cancer, senescence, and microRNAs. Cancer Res. 2011 Aug 15; 2011 Aug 9. PMID: 21828240

Goodwin EC, Lipovsky A, Inoue T, Magaldi TG, Edwards AP, Van Goor KE, Paton AW, Paton JC, Atwood WJ, Tsai B, DiMaio D: BiP and multiple DNAJ molecular chaperones in the endoplasmic reticulum are required for efficient simian virus 40 infection. MBio. 2011; 2011 Jun 14. PMID: 21673190

Marlatt SA, Kong Y, Cammett TJ, Korbel G, Noonan JP, Dimaio D: Construction and maintenance of randomized retroviral expression libraries for transmembrane protein engineering. Protein Eng Des Sel. 2011 Mar; 2010 Dec 10. PMID: 21149273

Martinez I, Almstead LL, DiMaio D: MicroRNAs and senescence. Aging (Albany NY). 2011 Feb. PMID: 21304181

Martinez I, Cazalla D, Almstead LL, Steitz JA, DiMaio D: miR-29 and miR-30 regulate B-Myb expression during cellular senescence. Proc Natl Acad Sci U S A. 2011 Jan 11; 2010 Dec 27. PMID: 21187425

Cammett TJ, Jun SJ, Cohen EB, Barrera FN, Engelman DM, Dimaio D: Construction and genetic selection of small transmembrane proteins that activate the human erythropoietin receptor. Proc Natl Acad Sci U S A. 2010 Feb 23; 2010 Feb 8. PMID: 20142506

Talbert-Slagle K, Marlatt S, Barrera FN, Khurana E, Oates J, Gerstein M, Engelman DM, Dixon AM, Dimaio D: Artificial transmembrane oncoproteins smaller than the bovine papillomavirus E5 protein redefine sequence requirements for activation of the platelet-derived growth factor beta receptor. J Virol. 2009 Oct; 2009 Jul 15. PMID: 19605488

Goodwin EC, Atwood WJ, DiMaio D: High-throughput cell-based screen for chemicals that inhibit infection by simian virus 40 and human polyomaviruses. J Virol. 2009 Jun; 2009 Mar 18. PMID: 19297472

Talbert-Slagle K, DiMaio D: The bovine papillomavirus E5 protein and the PDGF beta receptor: it takes two to tango. Virology. 2009 Feb 20; 2008 Nov 6. PMID: 18990418

Yates KE, Korbel GA, Shtutman M, Roninson IB, DiMaio D: Repression of the SUMO-specific protease Senp1 induces p53-dependent premature senescence in normal human fibroblasts. Aging Cell. 2008 Oct; 2008 Jul 24. PMID: 18616636

Liao JB, Publicover J, Rose JK, DiMaio D: Single-dose, therapeutic vaccination of mice with vesicular stomatitis virus expressing human papillomavirus type 16 E7 protein. Clin Vaccine Immunol. 2008 May; 2008 Mar 12. PMID: 18337377

Psyrri A, DiMaio D: Human papillomavirus in cervical and head-and-neck cancer. Nat Clin Pract Oncol. 2008 Jan. PMID: 18097454

DiMaio D, Miller G: Thirty years into the genomics era: tumor viruses led the way. Yale J Biol Med. 2006 Dec. PMID: 17940630

Lee BY, Han JA, Im JS, Morrone A, Johung K, Goodwin EC, Kleijer WJ, DiMaio D, Hwang ES: Senescence-associated beta-galactosidase is lysosomal beta-galactosidase. Aging Cell. 2006 Apr. PMID: 16626397

Sweasy JB, Lang T, DiMaio D: Is base excision repair a tumor suppressor mechanism? Cell Cycle. 2006 Feb; 2006 Feb 14. PMID: 16418580

DiMaio D, Liao JB: Human papillomaviruses and cervical cancer. Adv Virus Res. 2006. PMID: 16877060

Freeman-Cook LL, Dimaio D: Modulation of cell function by small transmembrane proteins modeled on the bovine papillomavirus E5 protein. Oncogene. 2005 Nov 21. PMID: 16299535

Sweasy JB, Lang T, Starcevic D, Sun KW, Lai CC, Dimaio D, Dalal S: Expression of DNA polymerase {beta} cancer-associated variants in mouse cells results in cellular transformation. Proc Natl Acad Sci U S A. 2005 Oct 4; 2005 Sep 22. PMID: 16179390

Lai CC, Edwards AP, DiMaio D: Productive interaction between transmembrane mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor beta receptor. J Virol. 2005 Feb. PMID: 15650217

Freeman-Cook LL, Edwards AP, Dixon AM, Yates KE, Ely L, Engelman DM, Dimaio D: Specific locations of hydrophilic amino acids in constructed transmembrane ligands of the platelet-derived growth factor beta receptor. J Mol Biol. 2005 Jan 28. PMID: 15588835

Freeman-Cook LL, Dixon AM, Frank JB, Xia Y, Ely L, Gerstein M, Engelman DM, DiMaio D: Selection and characterization of small random transmembrane proteins that bind and activate the platelet-derived growth factor beta receptor. J Mol Biol. 2004 May 14. PMID: 15111056

Psyrri A, DeFilippis RA, Edwards AP, Yates KE, Manuelidis L, DiMaio D: Role of the retinoblastoma pathway in senescence triggered by repression of the human papillomavirus E7 protein in cervical carcinoma cells. Cancer Res. 2004 May 1. PMID: 15126344

Horner SM, DeFilippis RA, Manuelidis L, DiMaio D: Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells. J Virol. 2004 Apr. PMID: 15047823

Irusta PM, Luo Y, Bakht O, Lai CC, Smith SO, DiMaio D: Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor. J Biol Chem. 2002 Oct 11; 2002 Aug 13. PMID: 12181311

DiMaio D, Mattoon D: Mechanisms of cell transformation by papillomavirus E5 proteins. Oncogene. 2001 Nov 26. PMID: 11753669

Goodwin EC, DiMaio D: Induced senescence in HeLa cervical carcinoma cells containing elevated telomerase activity and extended telomeres. Cell Growth Differ. 2001 Nov. PMID: 11714633

Mattoon D, Gupta K, Doyon J, Loll PJ, DiMaio D: Identification of the transmembrane dimer interface of the bovine papillomavirus E5 protein. Oncogene. 2001 Jun 28. PMID: 11439346

DiMaio D, Lai CC, Mattoon D: The platelet-derived growth factor beta receptor as a target of the bovine papillomavirus E5 protein. Cytokine Growth Factor Rev. 2000 Dec. PMID: 10959076

Goodwin EC, DiMaio D: Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways. Proc Natl Acad Sci U S A. 2000 Nov 7. PMID: 11070078

Wu L, Goodwin EC, Naeger LK, Vigo E, Galaktionov K, Helin K, DiMaio D: E2F-Rb complexes assemble and inhibit cdc25A transcription in cervical carcinoma cells following repression of human papillomavirus oncogene expression. Mol Cell Biol. 2000 Oct. PMID: 10982822

Goodwin EC, Yang E, Lee CJ, Lee HW, DiMaio D, Hwang ES: Rapid induction of senescence in human cervical carcinoma cells. Proc Natl Acad Sci U S A. 2000 Sep 26. PMID: 11005870

Lai CC, Henningson C, DiMaio D: Bovine papillomavirus E5 protein induces the formation of signal transduction complexes containing dimeric activated platelet-derived growth factor beta receptor and associated signaling proteins. J Biol Chem. 2000 Mar 31. PMID: 10734138

Drummond-Barbosa D, DiMaio D: Virocrine transformation. Biochim Biophys Acta. 1997 Feb 22. PMID: 9061007

Hwang ES, Naeger LK, DiMaio D: Activation of the endogenous p53 growth inhibitory pathway in HeLa cervical carcinoma cells by expression of the bovine papillomavirus E2 gene. Oncogene. 1996 Feb 15. PMID: 8632901

Kegler-Ebo DM, Polack GW, DiMaio D: Use of codon cassette mutagenesis for saturation mutagenesis. Methods Mol Biol. 1996. PMID: 8850016