Our Research

Read more about the individual projects of our lab members here.

Sreeganga Chandra

Chandra
My project involves identifying these toxic a-synuclein oligomers. I am taking advantage of Thy-1 human A30P a-synuclein transgenic mice, a mouse model for Parkinson’s disease.

Read More...

Karina Vargas

Vargas
Parkinson Disease (PD) is an age-related neurodegenerative disease. α-Synuclein plays a critical for familial and sporadic Parkinson Disease. This 14 KDa protein is highly expressed in the presynaptic compartment, but its function is still unknown.

Read More...

Chriss Westphal

Westphal
The synuclein proteins are a group of three small proteins – α-, β-, and γ-synuclein – whose precise function is unknown, and which my project aims to identify. I am using a variety of biochemical, biophysical, and cell biological methods to study synucleins’ interactions with membranes and other proteins.

Read More...

Mike Henderson

Henderson
In collaboration with Yongquan Zhang, I am investigating the cellular mechanism of synapse maintenance in a mouse model of neurodegeneration.

Read More...

Becket Greten-Harrison

Greten-Harrison
Synucleins have been shown to be a key player in the pathophysiology of Parkinson’s disease, yet they have also been shown to have a crucial role in synapse maintenance.

Read More...