Associate Professor of Pathology
Research Interests
- Calcification, Physiologic
- Osteoarthropathy, Primary Hypertrophic
- Pathology
- Pseudoxanthoma Elasticum
- Sickle Cell Trait
- Rare Diseases
- Vascular Calcification
Lab Members
Postdoctoral Associate
Research Interests- Aging
- Bone Diseases
- Cardiovascular Diseases
- Diabetes Mellitus
- Diabetes Complications
Research Associate 3, MS; Biotechnology Associate
Research Interests- Lupus Erythematosus, Systemic
- Chronic Kidney Disease-Mineral and Bone Disorder
- Purpura, Thrombocytopenic, Idiopathic
- Neutrophil Activation
- Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
- Rickets, Hypophosphatemic
Former Lab Members
Graduate Students
William Chozen Chang (2006-2012)
- Graduate Student, Yale Molecular Biophysics and Biochemistry (MB&B)
- Thesis: Autotaxin Structure, Function, & Inhibition
- Placement: FDA/CBER Division of Blood Products Evaluation and Research
Hsin-Hao Hsiao (2005-2010)
- Graduate Student, Yale Molecular Biophysics and Biochemistry (MB&B)
- Thesis: Structural Basis of FIR Mediated Transcription and Splicing
- Placement: Postdoctoral Fellow, NIH/NCI/ Laboratory of Pathology
Undergraduate Students
Mariel Covo (2015-2016)
- Yale Undergraduate, Ecology & Evolutionary Biology (EEB)
- Senior Thesis: Glycosylation and Catalytic rate of ENPP1: Novel modes of regulation for an essential enzyme
- Placement: VMD program, University of Pennsylvania School of Veterinary Medicine
Isabelle Mullen (2014-2016)
- Yale Undergraduate, Molecular Cell Biology, Genetics, and Development (MGCD)
- Senior Thesis: Physiologic function and therapeutic activity of ENPP1 in diseases of ectopic calcification
- Placement: City Year, New Orleans, LA
Anurag Deconda (2011-2013)
- Yale Undergraduate, Molecular Biophysics and Biochemistry (MB&B)
- Senior Thesis: Structural studies of ENPP4
- Placement: Columbia University, College of Physicians and Surgeons
Po-Han Chen (2003-2008)
- Yale Undergraduate, Molecular Biophysics and Biochemistry (MB&B)
- Senior Thesis: Crystallization of FIR/FUSE Protein-DNA Complexes
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Placement:
- 2008: Fulbright Scholar, Laboratory of Elena Conti, Director of the Max Plank Institute, Martinsried, Germany
- 2009-present: Northwestern Medical School, MD-PhD Program
Postdoctoral Fellows
James Zia (2012-2013)
- Fellow, Molecular Pathology
- Placement: Genentech, Pathology Department
Amy Ouellette (2006-2007)
- Postdoctoral Scientist
- Placement: Research Scientist, Ikonysis
Visiting Scientists
Logan Calderone (Summer 2016, Summer 2017)
- High School Intern, Hamden High School, Hamden, CT
- Placement: Washington University, St. Louis, MO
Aaron Wang (Summer 2015)
- High School Intern, Jericho High School, Jericho, NY
- 2016 Intel International Science and Engineering Fair Finalist
- Placement: Brown University, Providence, RI; UC-Berkeley, Berkeley, CA
Xiaomi Du (Summer 2011, Summer 2012)
- High School Intern
- Placement: California Institute of Technology, Pasadena, CA
Bonnie Hawkins (Summer 2010)
- High School Intern, Hamden High School, Hamden, CT
- Awards:
- 3rd Place, CT Junior Science and Humanities Symposium, 2011
- Invited Presenter, National Junior Science and Humanities Symposium 2011, San Diego, CA
- Finalist, CT Science, 2011
- Placement: Smith College, Northampton, MA
Isaac Young (Summer 2005; Fall 2010)
- Undergraduate, Calvin College
- Medical Student, UHSU, Bethesda MD
- Placement: Surgical Resident, Oregon Health Science University
Maxime Debrosse (2006-2007)
- STARS Post-Baccalaureate Year in Physical Science
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Placement:
- 2007: Rutgers Medical School
- 2009-2010: HHMI Medical Fellows Program, NIH