The Baserga Lab

The Baserga Lab studies yeast and ribosome biogenesis. Ribosome biogenesis is a complex process requiring the coordinated expression of rRNA and protein moieties and their assembly in the eukaryotic nucleolus. In order to better understand each aspect of this process, we are using an array of genetic, biochemical, biophysical, and cell biological techniques in humans, yeast and archaea. My laboratory focuses on the role of the ribonucleoprotein and protein complexes involved in generating the mature rRNAs.