Reproduction Publications

Bing X, Attardo GM, Vigneron A, Aksoy E, Scolari F, Malacrida A, Weiss BL, Aksoy S. Unravelling the relationship between the tsetse fly and its obligate symbiont Wigglesworthia: transcriptomic and metabolomic landscapes reveal highly integrated physiological networks. Proc Biol Sci. 2017;284(1857). doi: 10.1098/rspb.2017.0360. PubMed PMID: 28659447; PMCID: 5489720.

Scolari F, Benoit JB, Michalkova V, Aksoy E, Takac P, Abd-Alla AM, Malacrida AR, Aksoy S, Attardo GM. The Spermatophore in Glossina morsitans morsitans: Insights into Male Contributions to Reproduction. Sci Rep. 2016;6:20334. doi: 10.1038/srep20334. PubMed PMID: 26847001; PMCID: 4742874.

Michalkova V, Benoit JB, Weiss BL, Attardo GM, Aksoy S. Vitamin B6 generated by obligate symbionts is critical for maintaining proline homeostasis and fecundity in tsetse flies. Applied and environmental microbiology. 2014;80(18):5844-53. doi: 10.1128/AEM.01150-14. PubMed PMID: 25038091; PMCID: 4178588.

Benoit JB, Attardo GM, Baumann AA, Michalkova V, Aksoy S. Adenotrophic viviparity in tsetse flies: potential for population control and as an insect model for lactation. Annual review of entomology. 2015;60:351-71. doi: 10.1146/annurev-ento-010814-020834. PubMed PMID: 25341093.

Benoit JB, Attardo GM, Michalkova V, Krause TB, Bohova J, Zhang Q, Baumann AA, Mireji PO, Takac P, Denlinger DL, Ribeiro JM, Aksoy S. A novel highly divergent protein family identified from a viviparous insect by RNA-seq analysis: a potential target for tsetse fly-specific abortifacients. PLoS genetics. 2014;10(4):e1003874. doi: 10.1371/journal.pgen.1003874. PubMed PMID: 24763277; PMCID: 3998918.

Attardo GM, Benoit JB, Michalkova V, Patrick KR, Krause TB, Aksoy S. The homeodomain protein ladybird late regulates synthesis of milk proteins during pregnancy in the tsetse fly (Glossina morsitans). PLoS neglected tropical diseases. 2014;8(4):e2645. doi: 10.1371/journal.pntd.0002645. PubMed PMID: 24763082; PMCID: 3998940.

Michalkova V, Benoit JB, Attardo GM, Medlock J, Aksoy S. Amelioration of reproduction-associated oxidative stress in a viviparous insect is critical to prevent reproductive senescence. PloS one. 2014;9(4):e87554. doi: 10.1371/journal.pone.0087554. PubMed PMID: 24763119; PMCID: 3998933.

Benoit JB, Hansen IA, Attardo GM, Michalkova V, Mireji PO, Bargul JL, Drake LL, Masiga DK, Aksoy S. Aquaporins are critical for provision of water during lactation and intrauterine progeny hydration to maintain tsetse fly reproductive success. PLoS neglected tropical diseases. 2014;8(4):e2517. doi: 10.1371/journal.pntd.0002517. PubMed PMID: 24762803; PMCID: 3998938.

Baumann AA, Benoit JB, Michalkova V, Mireji PO, Attardo GM, Moulton JK, Wilson TG, Aksoy S. Juvenile hormone and insulin suppress lipolysis between periods of lactation during tsetse fly pregnancy. Molecular and cellular endocrinology. 2013;372(1-2):30-41. doi: 10.1016/j.mce.2013.02.019. PubMed PMID: 23499946; PMCID: 4222070.

Wang J, Aksoy S. PGRP-LB is a maternally transmitted immune milk protein that influences symbiosis and parasitism in tsetse's offspring. Proceedings of the National Academy of Sciences of the United States of America. 2012;109(26):10552-7. doi: 10.1073/pnas.1116431109. PubMed PMID: 22689989; PMCID: 3387098.

Attardo GM, Benoit JB, Michalkova V, Yang G, Roller L, Bohova J, Takáč P,Aksoy S. Analysis of lipolysis underlying lactation in the tsetse fly, Glossina morsitans. Insect Biochem Mol Biol. 2012 May;42(5):360-70. PubMed PMID: 22509523.

Benoit JB, Attardo GM, Michalkova V, Takac P, Bohova J, Aksoy S. Sphingomyelinase Activity in Mother's Milk Is Essential for Juvenile Development: A Case from Lactating Tsetse Flies. Biol Reprod. 2012 Apr 18. [Epub ahead of print] PubMed PMID: 22517621.

Benoit JB, Yang G, Krause TB, Patrick KR, Aksoy S, Attardo GM. Lipophorin acts as a shuttle of lipids to the milk gland during tsetse fly pregnancy. J Insect Physiol. 2011 Nov;57(11):1553-61. Epub 2011 Aug 22. PubMed PMID: 21875592; PubMed Central PMCID: PMC3209505.

Yang G, Attardo GM, Lohs C, Aksoy S. Molecular characterization of two novel milk proteins in the tsetse fly (Glossina morsitans morsitans). Insect Mol Biol. 2010 Apr;19(2):253-62. Epub 2010 Feb 1. PubMed PMID: 20136662; PubMed Central PMCID: PMC2862765.

Attardo GM, Lohs C, Heddi A, Alam UH, Yildirim S, Aksoy S. Analysis of milk gland structure and function in Glossina morsitans: milk protein production, symbiont populations and fecundity. J Insect Physiol. 2008 Aug;54(8):1236-42. Epub 2008 Jul 4. PubMed PMID: 18647605; PubMed Central PMCID: PMC2613686.

Hu C, Rio RV, Medlock J, Haines LR, Nayduch D, Savage AF, Guz N, Attardo GM, Pearson TW, Galvani AP, Aksoy S. Infections with immunogenic trypanosomes reduce tsetse reproductive fitness: potential impact of different parasite strains on vector population structure. PLoS Negl Trop Dis. 2008 Mar 12;2(3):e192. PubMed PMID: 18335067; PubMed Central PMCID: PMC2265429.

Guz N, Attardo GM, Wu Y, Aksoy S. Molecular aspects of transferrin expression in the tsetse fly (Glossina morsitans morsitans). J Insect Physiol. 2007 Jul;53(7):715-23. Epub 2007 Apr 1. PubMed PMID: 17498733; PubMed Central PMCID: PMC2065764.

Strickler-Dinglasan PM, Guz N, Attardo G, Aksoy S. Molecular characterization of iron binding proteins from Glossina morsitans morsitans (Diptera: Glossinidae). Insect Biochem Mol Biol. 2006 Dec;36(12):921-33. Epub 2006 Sep 26. PubMed PMID: 17098167; PubMed Central PMCID: PMC1698469.

Attardo GM, Guz N, Strickler-Dinglasan P, Aksoy S. Molecular aspects of viviparous reproductive biology of the tsetse fly (Glossina morsitans morsitans): regulation of yolk and milk gland protein synthesis. J Insect Physiol. 2006 Nov-Dec;52(11-12):1128-36. Epub 2006 Sep 5. PubMed PMID: 17046784; PubMed Central PMCID: PMC1779500.