Pitt Publications


Concise review: modeling multiple sclerosis with stem cell biological platforms: toward functional validation of cellular and molecular phenotypes in inflammation-induced neurodegeneration.

Orack JC, Deleidi M, Pitt D, Mahajan K, Nicholas JA, Boster AL, Racke MK, Comabella M, Watanabe F, Imitola J.

Stem Cells Transl Med. 2015 Mar;4 (3) :252-60. Epub 2015 Jan 15. PMID: 25593207


Quantitative susceptibility mapping (QSM) of white matter multiple sclerosis lesions: Interpreting positive susceptibility and the presence of iron.

Wisnieff C, Ramanan S, Olesik J, Gauthier S, Wang Y, Pitt D.

Magn Reson Med. 2014 Aug 18; Epub 2014 Aug 18. PMID: 25137340


B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes.

Stern JN, Yaari G, Vander Heiden JA, Church G, Donahue WF, Hintzen RQ, Huttner AJ, Laman JD, Nagra RM, Nylander A, Pitt D, Ramanan S, Siddiqui BA, Vigneault F, Kleinstein SH, Hafler DA, O'Connor KC.

Sci Transl Med. 2014 Aug 6;6 (248) :248ra107. PMID: 25100741


Quantitative susceptibility mapping of multiple sclerosis lesions at various ages.

Chen W, Gauthier SA, Gupta A, Comunale J, Liu T, Wang S, Pei M, Pitt D, Wang Y.

Radiology. 2014 Apr;271 (1) :183-92. Epub 2013 Nov 18. PMID: 24475808


IFN-β alters neurotrophic factor expression in T cells isolated from multiple sclerosis patients - implication of novel neurotensin/NTSR1 pathway in neuroprotection.

Soltys J, Knight J, Scharf E, Pitt D, Mao-Draayer Y.

Am J Transl Res. 2014;6 (3) :312-9. Epub 2014 May 15. PMID: 24936223


Macrophage migration inhibitory factor potentiates autoimmune-mediated neuroinflammation.

Cox GM, Kithcart AP, Pitt D, Guan Z, Alexander J, Williams JL, Shawler T, Dagia NM, Popovich PG, Satoskar AR, Whitacre CC.

J Immunol. 2013 Aug 1;191 (3) :1043-54. Epub 2013 Jun 24. PMID: 23797673


Lessons learned from fatal progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with natalizumab.

Boster AL, Nicholas JA, Topalli I, Kisanuki YY, Pei W, Morgan-Followell B, Kirsch CF, Racke MK, Pitt D.

JAMA Neurol. 2013 Mar 1;70 (3) :398-402. PMID: 23338729


Iron is a sensitive biomarker for inflammation in multiple sclerosis lesions.

Mehta V, Pei W, Yang G, Li S, Swamy E, Boster A, Schmalbrock P, Pitt D.

PLoS One. 2013;8 (3) :e57573. Epub 2013 Mar 14. PMID: 23516409


Detecting cortical lesions in multiple sclerosis at 7 T using white matter signal attenuation.

Bluestein KT, Pitt D, Sammet S, Zachariah CR, Nagaraj U, Knopp MV, Schmalbrock P.

Magn Reson Imaging. 2012 Sep;30 (7) :907-15. Epub 2012 May 11. PMID: 22578928


T1 and proton density at 7 T in patients with multiple sclerosis: an initial study.

Bluestein KT, Pitt D, Knopp MV, Schmalbrock P.

Magn Reson Imaging. 2012 Jan;30 (1) :19-25. Epub 2011 Sep 19. PMID: 21937183


What happens when natalizumab therapy is stopped?

Schaaf SM, Pitt D, Racke MK.

Expert Rev Neurother. 2011 Sep;11 (9) :1247-50. PMID: 21864070


Efficacy, safety, and cost-effectiveness of glatiramer acetate in the treatment of relapsing-remitting multiple sclerosis.

Boster A, Bartoszek MP, O'Connell C, Pitt D, Racke M.

Ther Adv Neurol Disord. 2011 Sep;4 (5) :319-32. PMID: 22010043


TMDL implementation in agricultural landscapes: a communicative and systemic approach.

Jordan NR, Slotterback CS, Cadieux KV, Mulla DJ, Pitt DG, Olabisi LS, Kim JO.

Environ Manage. 2011 Jul;48 (1) :1-12. Epub 2011 Mar 10. PMID: 21547434


Imaging cortical lesions in multiple sclerosis with ultra-high-field magnetic resonance imaging.

Pitt D, Boster A, Pei W, Wohleb E, Jasne A, Zachariah CR, Rammohan K, Knopp MV, Schmalbrock P.

Arch Neurol. 2010 Jul;67 (7) :812-8. PMID: 20625086


Dysmyelinated axons in shiverer mice are highly vulnerable to alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor-mediated toxicity.

Pitt D, Gonzales E, Cross AH, Goldberg MP.

Brain Res. 2010 Jan 14;1309 :146-54. Epub 2009 Nov 4. PMID: 19896473


Assessing the impact of suicide exclusion periods on life insurance.

Yip P, Pitt D, Wang Y, Wu X, Watson R, Huggins R, Xu Y.

Crisis. 2010;31 (4) :217-23. PMID: 20801752


Glutamate uptake by oligodendrocytes: Implications for excitotoxicity in multiple sclerosis.

Pitt D, Nagelmeier IE, Wilson HC, Raine CS.

Neurology. 2003 Oct 28;61 (8) :1113-20. PMID: 14581674


Experimental autoimmune encephalomyelitis (EAE) in CCR2(-/-) mice: susceptibility in multiple strains.

Gaupp S, Pitt D, Kuziel WA, Cannella B, Raine CS.

Am J Pathol. 2003 Jan;162 (1) :139-50. PMID: 12507897


Multiple sclerosis: altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage.

Werner P, Pitt D, Raine CS.

Ann Neurol. 2001 Aug;50 (2) :169-80. PMID: 11506399


Insulin-like growth factor-1 fails to enhance central nervous system myelin repair during autoimmune demyelination.

Cannella B, Pitt D, Capello E, Raine CS.

Am J Pathol. 2000 Sep;157 (3) :933-43. PMID: 10980132


Glutamate excitotoxicity--a mechanism for axonal damage and oligodendrocyte death in Multiple Sclerosis?

Werner P, Pitt D, Raine CS.

J Neural Transm Suppl. 2000; (60) :375-85. PMID: 11205156


Glutamate excitotoxicity in a model of multiple sclerosis.

Pitt D, Werner P, Raine CS.

Nat Med. 2000 Jan;6 (1) :67-70. PMID: 10613826


Neuregulin and erbB receptor expression in normal and diseased human white matter.

Cannella B, Pitt D, Marchionni M, Raine CS.

J Neuroimmunol. 1999 Dec;100 (1-2) :233-42. PMID: 10695733