Sequencing costs for specific applications:
Recent R&D efforts at YCGA for analyzing pooled samples has resulted in increased throughput and significant cost savings for various applications. Since one lane of a HiSeq flowcell provides sequence for approximately 30 billion bases, it is possible to sequence multiple barcoded samples in one lane and still obtain sufficient coverage for each of the pooled samples. The following table provides costs for the most common applications. We guarantee 88% 8x coverage for pooled exome analysis. If you need further information, please contact us.
# of barcoded exomes captured
Approx. # of millions of
Detection of somatic variations/
Identification of denovo mutations
Discovery of Mendelian/
*Yale Prices as of 7/1/2013