Mass Spectrometry

FT-ICR

Uses

  • Exact/Accurate mass of small molecules, peptides, oligos (RNA/DNA), lipids, intact proteins, drugs, etc. for determining elemental composition
  • Structural Elucidation of small molecule; Use of multi-fragmentation techniques of FT-ICR for small molecules to determine structural information.
  • Protein Post Translational Modification
  • Protein Identification & Peptide sequencing
  • Comparative protein/peptide profiling

Advantages of FT-ICR

  • Ultra High Resolution for separation of molecular masses less than 0.002 Da
  • High Mass Accuracy (<3ppm with Ext. Calibration) for elemental assignment
  • Multi-fragmentation capabilities for structural elucidation and protein PTM analysis
  • Protein Identification & Peptide sequencing
  • Comparative protein/peptide profiling.