Keck MS & Proteomics Resource Publications

1980-1989

52. Williams, K. R., Hemmings, H. C., Jr., LoPresti, M. B., and Greengard, P. (1989) ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Amino acid sequence of ARPP-21B from bovine caudate nucleus. J Neurosci 9, 3631-3637.

51. Stone, K. L., LoPresti, M. L., Williams, N. D., Crawford, J. M., DeAngeles, R., and Williams, K. R. (1989) Enzymatic digestion of proteins and HPLC peptide isolation in the sub-nanomole range, in Techniques in Protein Chemistry, (Hugli, T. E. ed), Academic Press, New York, 377-391.

50. Stone, K. L., LoPresti, M. B., Crawford, J. M., DeAngelis, R., and Williams, K. R. (1989) Enzymatic digestion of proteins and HPLC peptide isolation, in A Practical Guide to Protein and Peptide Purification for Microsequencing, (Matsudaira, P. ed), Academic Press, New York, 33-47.

49. Rush, J., Lin, T. C., Quinones, M., Spicer, E. K., Douglas, I., Williams, K. R., and Konigsberg, W. H. (1989) The 44P subunit of the T4 DNA polymerase accessory protein complex catalyzes ATP hydrolysis. J. Biol. Chem. 264, 10943-10953.

48. Niece, R. L., Williams, K. R., Wadsworth, C. L., Elliott, J., Stone, K. L., McMurray, W. J., Fowler, A., Atherton, D., Kutny, R., and Smith, A. (1989) A synthetic peptide for evaluating protein sequencer and amino acid analyzer performance in core facilities: Design and results, in Techniques in Protein Chemistry, (Hugli, T. E. ed), Academic Press, New York, 89-101.

47. Merrill, B. M., Barnett, S. F., LeStourgeon, W. M., and Williams, K. R. (1989) Primary structure differences between proteins C1 and C2 of HeLa 40S nuclear ribonucleoprotein particles. Nucleic Acids Res. 17, 8441-8449, (PMCID: PMC 335017).

46. Hemmings, H. C., Jr., Girault, J. A., Williams, K. R., LoPresti, M. B., and Greengard, P. (1989) ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro. J. Biol. Chem. 264, 7726-7733.

45. Girault, J. A., Hemmings, H. C., Jr., Williams, K. R., Nairn, A. C., and Greengard, P. (1989) Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II. J. Biol. Chem. 264, 21748-21759.

44. Elliott, J., Stone, K., Roberts, W., LoPresti, M., Crawford, M., Kapouch, J., Jacobsen, E., Williams, K. R., McMurray, W., Meng, C., Mann, M., and Fenn, J. (1989) Structure of symposium test peptide-3, in Techniques in Protein Chemistry, (Hugli, T. E. ed), Academic Press, New York, 569-579.

43. Stone, K. L., and Williams, K. (1988) Small bore HPLC purification of peptides in the subnanomole range, in Macromolecular Sequencing and Synthesis, (Schlesinger, D. H. ed), Alan R. Liss, New York, 7-24.

42. Shamoo, Y., Williams, K. R., and Konigsberg, W. H. (1988) Photochemical crosslinking of bacteriophage T4 single-stranded DNA-binding protein (gp32) to oligo-p(dT)8: identification of phenylalanine-183 as the site of crosslinking. Proteins 4, 1-6.

41. Merrill, B. M., Stone, K. L., Cobianchi, F., Wilson, S. H., and Williams, K. R. (1988) Phenylalanines that are conserved among several RNA-binding proteins form part of a nucleic acid-binding pocket in the A1 heterogeneous nuclear ribonucleoprotein. J. Biol. Chem. 263, 3307-3313.

40. Cobianchi, F., Karpel, R. L., Williams, K. R., Notario, V., and Wilson, S. H. (1988) Mammalian heterogeneous nuclear ribonucleoprotein complex protein A1. Large-scale overproduction in Escherichia coli and cooperative binding to single-stranded nucleic acids. J. Biol. Chem. 263, 1063-1071.

39. Williams, K. R., Stone, K. L., Fritz, M. K., Merrill, B. M., Konigsberg, W. H., Pandolfo, M., Valentini, O., Reddigari, S., Patel, G. L., and Chase, J. W. (1987) Use of HPLC comparative peptide mapping in structure/function studies., in Proteins: Structure and Function., (L'Italien, J. J. ed), 45-52.

38. Spicer, E. K., Horton, R., Bloem, L., Bach, R., Williams, K. R., Guha, A., Kraus, J., Lin, T. C., Nemerson, Y., and Konigsberg, W. H. (1987) Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA. Proc. Natl. Acad. Sci. U. S. A. 84, 5148-5152, (PMCID: PMC 298811).

37. Pandey, V. N., Williams, K. R., Stone, K. L., and Modak, M. J. (1987) Photoaffinity labeling of the thymidine triphosphate binding domain in Escherichia coli DNA polymerase I: identification of histidine-881 as the site of cross-linking. Biochemistry 26, 7744-7748.

36. Merrill, B. M., Lopresti, M. B., Stone, K. L., and Williams, K. R. (1987) Amino acid sequence of UP1, an hnRNP-derived single-stranded nucleic acid binding protein from calf thymus. Int. J. Pept. Protein Res. 29, 21-39.

35. Coleman, J. E., Williams, K. R., King, G. C., Prigodich, R. V., Shamoo, Y., and Konigsberg, W. H. (1987) Mapping the functional domains in single-strand DNA-binding proteins gene 5 and gene 32. , in Protein Engineering, (Oxender, D., and Fox, C. F. ed), Alan R. Liss, N.Y., 323-336.

34. Basu, A., Williams, K. R., and Modak, M. J. (1987) Ferrate oxidation of Escherichia coli DNA polymerase-I. Identification of a methionine residue that is essential for DNA binding. J. Biol. Chem. 262, 9601-9607.

33. Williams, K. R., Williams, N. D., Konigsberg, W., and Yu, R. K. (1986) Acidic lipids enhance cathepsin D cleavage of the myelin basic protein. J. Neurosci. Res. 15, 137-145.

32. Williams, K. R., Hemmings, H. C., Jr., LoPresti, M. B., Konigsberg, W. H., and Greengard, P. (1986) DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1. J. Biol. Chem. 261, 1890-1903.

31. Stone, K.L., Williams, K.R., Rabin, B.A., Murphy, J.B., Chase, J.W. and Pfeifer, R. (1986) HPLC purification and identification of peptides using microbore columns. Waters Journal, 20-27.

30. Stone, K. L., and Williams, K. R. (1986) High-performance liquid chromatographic peptide mapping and amino acid analysis in the sub-nanomole range. J. Chromatogr. 359, 203-212.

29. Shamoo, Y., Adari, H., Konigsberg, W. H., Williams, K. R., and Chase, J. W. (1986) Cloning of T4 gene 32 and expression of the wild-type protein under lambda promoter PL regulation in Escherichia coli. Proc. Natl. Acad. Sci. U. S. A. 83, 8844-8848, (PMCID: PMC 387029).

28. Riva, S., Morandi, C., Tsoulfas, P., Pandolfo, M., Biamonti, G., Merrill, B., Williams, K. R., Multhaup, G., Beyreuther, K., Werr, H., and et al. (1986) Mammalian single-stranded DNA binding protein UP I is derived from the hnRNP core protein A1. EMBO J. 5, 2267-2273, (PMCID: PMC 1167110).

27. Merrill, B. M., LoPresti, M. B., Stone, K. L., and Williams, K. R. (1986) High pressure liquid chromatography purification of UP1 and UP2, two related single-stranded nucleic acid-binding proteins from calf thymus. J. Biol. Chem. 261, 878-883.

26. Kumar, A., Williams, K. R., and Szer, W. (1986) Purification and domain structure of core hnRNP proteins A1 and A2 and their relationship to single-stranded DNA-binding proteins. J. Biol. Chem. 261, 11266-11273.

25. Kraus, J. P., Firgaira, F., Novotny, J., Kalousek, F., Williams, K. R., Williamson, C., Ohura, T., and Rosenberg, L. E. (1986) Coding sequence of the precursor of the beta subunit of rat propionyl-CoA carboxylase. Proc. Natl. Acad. Sci. U. S. A. 83, 8049-8053, (PMCID: PMC 386864).

24. Coleman, J. E., Williams, K. R., King, G. C., Prigodich, R. V., Shamoo, Y., and Konigsberg, W. H. (1986) Protein chemistry-nuclear magnetic resonance approach to mapping functional domains in single-stranded DNA binding proteins. J. Cell. Biochem 32, 305-326.

23. Chase, J. W., Rabin, B. A., Murphy, J. B., Stone, K. L., and Williams, K. R. (1986) Escherichia coli exonuclease VII. Cloning and sequencing of the gene encoding the large subunit (xseA). J. Biol. Chem. 261, 14929-14935.

22. Williams, K. R., Stone, K. L., LoPresti, M. B., Merrill, B. M., and Planck, S. R. (1985) Amino acid sequence of the UP1 calf thymus helix-destabilizing protein and its homology to an analogous protein from mouse myeloma. Proc. Natl. Acad. Sci. U. S. A. 82, 5666-5670, (PMCID: PMC 390612).

21. Williams, K. R., Reddigari, S., and Patel, G. L. (1985) Identification of a nucleic acid helix-destabilizing protein from rat liver as lactate dehydrogenase-5. Proc. Natl. Acad. Sci. U. S. A. 82, 5260-5264, (PMCID: PMC 390547).

20. Kraus, J. P., Hodges, P. E., Williamson, C. L., Horwich, A. L., Kalousek, F., Williams, K. R., and Rosenberg, L. E. (1985) A cDNA clone for the precursor of rat mitochondrial ornithine transcarbamylase: comparison of rat and human leader sequences and conservation of catalytic sites. Nucleic Acids Res. 13, 943-952, (PMCID: PMC 341044).

19. Chase, J. W., Flory, J., Ruddle, N. H., Murphy, J. B., and Williams, K. R. (1985) A monoclonal antibody that recognizes the functional domain of Escherichia coli single-stranded DNA binding protein that includes the ssb-113 mutation. J. Biol. Chem. 260, 7214-7218.

18. Adari, H. Y., Rose, K., Williams, K. R., Konigsberg, W. H., Lin, T. C., and Spicer, E. K. (1985) Cloning, nucleotide sequence, and overexpression of the bacteriophage T4 regA gene. Proc. Natl. Acad. Sci. U. S. A. 82, 1901-1905, (PMCID: PMC 397441).

17. Williams, K. R., Murphy, J. B., and Chase, J. W. (1984) Characterization of the structural and functional defect in the Escherichia coli single-stranded DNA binding protein encoded by the ssb-1 mutant gene. Expression of the ssb-1 gene under lambda pL regulation. J. Biol. Chem. 259, 11804-11811.

16. Spicer, E. K., Nossal, N. G., and Williams, K. R. (1984) Bacteriophage T4 gene 44 DNA polymerase accessory protein. Sequences of gene 44 and its protein product. J. Biol. Chem. 259, 15425-15432.

15. Patel, G., Reddigari, S., Williams, K. R., Baptist, E., Thompson, P., and Sisodia, S. (1984) A rat liver helix-destabilizing protein: properties and homology to LDH-5. , in Growth, Cancer, and the Cell Cycle, (Skehan, P., and Friedman, S. J. ed), Humana Press, Clifton, N.J., 41-58.

14. Paradiso, P. R., Williams, K. R., and Costantino, R. L. (1984) Mapping of the amino terminus of the H-1 parvovirus major capsid protein. J. Virol. 52, 77-81, (PMCID: PMC 254491).

13. Merrill, B. M., Williams, K. R., Chase, J. W., and Konigsberg, W. H. (1984) Photochemical cross-linking of the Escherichia coli single-stranded DNA-binding protein to oligodeoxynucleotides. Identification of phenylalanine 60 as the site of cross-linking. J. Biol. Chem. 259, 10850-10856.

12. Horwich, A. L., Fenton, W. A., Williams, K. R., Kalousek, F., Kraus, J. P., Doolittle, R. F., Konigsberg, W., and Rosenberg, L. E. (1984) Structure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase. Science 224, 1068-1074.

11. Hemmings, H. C., Jr., Williams, K. R., Konigsberg, W. H., and Greengard, P. (1984) DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. I. Amino acid sequence around the phosphorylated threonine. J. Biol. Chem. 259, 14486-14490.

10. Chase, J. W., L'Italien, J. J., Murphy, J. B., Spicer, E. K., and Williams, K. R. (1984) Characterization of the Escherichia coli SSB-113 mutant single-stranded DNA-binding protein. Cloning of the gene, DNA and protein sequence analysis, high pressure liquid chromatography peptide mapping, and DNA-binding studies. J. Biol. Chem. 259, 805-814.

9. Williams, K. R., Spicer, E. K., LoPresti, M. B., Guggenheimer, R. A., and Chase, J. W. (1983) Limited proteolysis studies on the Escherichia coli single-stranded DNA binding protein. Evidence for a functionally homologous domain in both the Escherichia coli and T4 DNA binding proteins. J. Biol. Chem. 258, 3346-3355.

8. Williams, K., and Konigsberg, W. (1983) Structure-function relationships in the T4 single-stranded DNA binding protein, in Bacteriophage T4 Monograph, American Society for Microbiology 82-89.

7. Horwich, A. L., Kraus, J. P., Williams, K., Kalousek, F., Konigsberg, W., and Rosenberg, L. E. (1983) Molecular cloning of the cDNA coding for rat ornithine transcarbamoylase. Proc. Natl. Acad. Sci. U. S. A. 80, 4258-4262, (PMCID: PMC 384016).

6. Chase, J. W., Merrill, B. M., and Williams, K. R. (1983) F sex factor encodes a single-stranded DNA binding protein (SSB) with extensive sequence homology to Escherichia coli SSB. Proc. Natl. Acad. Sci. U. S. A. 80, 5480-5484, (PMCID: PMC 384281).

5. Williams, K., L'Italien, J., Guggenheimer, R., Sillerud, L., Spicer, E. K., Chase, J. W., and Konigsberg, W. H. (1982) Comparative peptide mapping by HPLC: identification of single amino acid substitutions in temperature sensitive mutants, in Methods in Protein Sequence Analysis, Humana Press, Clifton, N.J., 499-507.

4. Spicer, E. K., Noble, J. A., Nossal, N. G., Konigsberg, W. H., and Williams, K. R. (1982) Bacteriophage T4 gene 45. Sequences of the structural gene and its protein product. J. Biol. Chem. 257, 8972-8979.

3. Williams, K. R., LoPresti, M. B., and Setoguchi, M. (1981) Primary structure of the bacteriophage T4 DNA helix-destabilizing protein. J. Biol. Chem. 256, 1754-1762.

2. Sancar, A., Williams, K. R., Chase, J. W., and Rupp, W. D. (1981) Sequences of the ssb gene and protein. Proc. Natl. Acad. Sci. U. S. A. 78, 4274-4278, (PMCID: PMC 319772).

1. Williams, K. R., LoPresti, M. B., Setoguchi, M., and Konigsberg, W. H. (1980) Amino acid sequence of the T4 DNA helix-destabilizing protein. Proc. Natl. Acad. Sci. U. S. A. 77, 4614-4617, (PMCID: PMC 349895).