Yorgo Eugene Modis PhD
Associate Professor of Molecular Biophysics and Biochemistry
Departments & Organizations
Biological and Biomedical Sciences (BBS): Microbiology | Biochemistry, Biophysics and Structural Biology: Membrane Biology and Motion; Virology, Infection and Immunity
Structural Biology
Molecular Biophysics and Biochemistry: Biology and Structure of Membrane Proteins | Structural Biology | Mechanisms of Viral Pathogenesis | Area: Biology and Structure of Membrane Proteins
Molecular Virology
Research Interests
Bacterial Infections; Biochemistry; Biophysics; Disease Resistance; Immune System; Immune System Disorders; Immunology; Infectious Diseases or Agents; Inflammatory Bowel Disease; Natural Processes Health Safety Medical; Pathogenesis; Receptors; Structural Biology; Structure or Function (Health or Safety or Medical); Vaccine more...
Education
- Ph.D., European Molecular Biology Laboratorium (EMBL), 1999
Selected Publications
- Berke IC, Modis Y (2012) MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA. EMBO J 31:1714-26.
- Li Y, Berke IC, Modis Y (2012) DNA binding to proteolytically activated TLR9 is sequence-independent and enhanced by DNA curvature. EMBO J 31:919-31
- Zhou k, Kanai R, Lee P, Wang HW, Modis Y (2012) Toll-like receptor 5 forms asymmetric dimers in the absence of flagellin. J Struct Biol 77:402-9.
