Yorgo Eugene Modis PhD

Research Scientist in Molecular Biophysics and Biochemistry

Departments & Organizations

Structural Biology

Molecular Biophysics and Biochemistry: Biology and Structure of Membrane Proteins | Structural Biology | Mechanisms of Viral Pathogenesis

Molecular Virology

Research Interests

Bacterial Infections; Biochemistry; Biophysics; Disease Resistance; Immune System; Immune System Disorders; Immunology; Infectious Diseases or Agents; Inflammatory Bowel Disease; Natural Processes Health Safety Medical; Pathogenesis; Receptors; Structural Biology; Structure or Function (Health or Safety or Medical); Vaccine more...


  • Ph.D., European Molecular Biology Laboratorium (EMBL), 1999

Selected Publications

  • Berke IC, Modis Y (2012) MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA. EMBO J 31:1714-26.
  • Li Y, Berke IC, Modis Y (2012) DNA binding to proteolytically activated TLR9 is sequence-independent and enhanced by DNA curvature. EMBO J 31:919-31
  • Zhou k, Kanai R, Lee P, Wang HW, Modis Y (2012) Toll-like receptor 5 forms asymmetric dimers in the absence of flagellin. J Struct Biol 77:402-9.



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