Xenophon Papademetris, PhD

Associate Professor of Diagnostic Radiology and of Biomedical Engineering

Research Interests

Research Organizations

Diagnostic Radiology: Bioimaging Sciences: BioImage Suite; Image Processing & Analysis Group; Magnetic Resonance Research Center | Quantitative Neuroscience with Magnetic Resonance

Discovery to Cure Internship

Yale Translational Research Imaging Center (Y-TRIC)

Research Summary

Dr. Xenophon Papademetris's research is currently focused on three main areas: (i) brain deformation modeling and compensation during neurosurgical interventions, as well as complex 3D visualization of multimodal image data for surgical planning and guidance; (ii) Medical Image Analysis software development – primarily the BioImage Suite project (see www.bioimagesuite.org); and (iii) vascular image analysis, both in terms of monitoring angiogenesis and in the quantification of the growth of tissue engineered vessels.

Selected Publications

  • A non-parametric vessel detection method for complex vascular structures. Qian X, Brennan MP, Dione DP, Dobrucki WL, Jackowski MP, Breuer CK, Sinusas AJ, Papademetris X. Med Image Anal. 2009 Feb;13(1):49-61. Epub 2008 Jun 14. PMID: 18678521 [
  • Effective visualization of complex vascular structures using a non-parametric vessel detection method. Joshi A, Qian X, Dione DP, Bulsara KR, Breuer CK, Sinusas AJ, Papademetris X. IEEE Trans Vis Comput Graph. 2008 Nov-Dec;14(6):1603-10. PMID: 18989016
  • From medical image computing to computer-aided intervention: development of a research interface for image-guided navigation. Papademetris X, DeLorenzo C, Flossmann S, Neff M, Vives KP, Spencer DD, Staib LH, Duncan JS. Int J Med Robot. 2009 Jun;5(2):147-5
  • Shape Comparison Using Perturbing Shape Registration. Jiang Y, Edmiston E, Wang F, Blumberg HP, Staib LH, Papademetris X. Proc IEEE Comput Soc Conf Comput Vis Pattern Recognit. 2009 Jun 20;2009:683-690. PMID: 20386618 [PubMed]
  • A non-rigid registration method for serial lower extremity hybrid SPECT/CT imaging. Suh JW, Scheinost D, Dione DP, Dobrucki LW, Sinusas AJ, Papademetris X. Med Image Anal. 2011 Feb;15(1):96-111. Epub 2010 Sep 24.
  • Unified framework for development, deployment and robust testing of neuroimaging algorithms. Joshi A, Scheinost D, Okuda H, Belhachemi D, Murphy I, Staib LH, Papademetris X. Neuroinformatics. 2011 Mar;9(1):69-84.
  • Vascular Tree Reconstruction by Minimizing A Physiological Functional Cost. Jiang Y, Zhuang Z, Sinusas AJ, Papademetris X. Conf Comput Vis Pattern Recognit Workshops. 2010 Jun 13:178-185.

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Contact Info

Xenophon Papademetris, PhD
Office Location
The Anlyan Center
300 Cedar Street, Ste Suite N119

New Haven, CT 06519
Mailing Address
Diagnostic RadiologyPO Box 208043
TAC N119

New Haven, CT 06520-8043

BioImage Suite Project