Titus Boggon PhD
Associate Professor of Pharmacology
Departments & Organizations
Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural Biology: Cell Cycle and Signal Transduction; Drug Design, Discovery and Mechanism; Membrane Biology and Motion
Signal Transduction
Structural Biology
Pharmacology
Signal Transduction
Research Interests
Structural biology of signal transduction more...
Education
- BS, University of Manchester, UK, 1995
- Ph.D., University of Manchester, UK, 1998
Selected Publications
- Li X, Ji W, Zhang R, Folta-Stogniew E, Min W, Boggon TJ. Molecular recognition of leucine-aspartate repeat (LD) motifs by the focal adhesion targeting-homology domain of cerebral cavernous malformation 3 (CCM3). Journal of Biological Chemistry. 2011; 286(29):26138-26147
- Li X*, Zhang R*, Zhang H, He Y, Ji W, Min W‡, Boggon TJ‡. Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity. Journal of Biological Chemistry. 2010; 285(31):24099-24107.
- Petri ET, Celic AS, Kennedy SD, Ehrlich BE, Boggon TJ‡, Hodsdon ME‡. Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+ -dependent regulation of polcystin-2 channel activity. PNAS. 2010; 107(20):9176-81
