Therapeutic Radiology Faculty

Glazer, Peter M.

Chair and Chief

Research Interests:Gene targeting and gene therapy; Genetic instability in cancer; Mutagenesis; DNA repair; Radiation resistance; Cellular responses to radiation

Clinical Interests:General radiation therapy; breast cancer; prostate cancer; lung cancer

Wilson, Lynn D.

Vice Chair and Clinical Director

Research Interests:Cutaneous Lymphoma; Lung cancer; Total Skin Electron Beam Therapy

Clinical Interests:Cutaneous lymphoma, Lung cancer, Benign and malignant tumors of the skin, Breast cancer; Thoracic cancer

Sweasy, Joann Balazs

Vice Chair for Basic Research

Research Interests:Genome Stability; Mutagenesis; DNA Replication; DNA Repair; Carcinogenesis

Ahmad, Munir

Research Interests:Monte Carlo-Based Radiation Treatment Planning; Development of Simultaneous-Integrated Boost (SIB) IMRT Techniques for Dose Escalation to Enhance Tumor Control Probability (TCP) and to Reduce Normal Tissue Complication Probability (NTCP); Radiobiological Models for Designing New Fractionation Strategies in 3-D Conformal Radiotherapy

Clinical Interests:Intensity-Modulated Radiation Therapy (IMRT); Image-Guided Adaptive Radiation Therapy (IGART); Stereotactic Radiosurgery; Electron Arc Therapy (EAT): Treatment Planning and Delivery; Interstitial and Intracavitary Brachytherapy; Reference Dosimetry and Quality Assurance in Radiotherapy

Baserga, Susan J

Research Interests:Ribosome biogenesis; RRNA processing; U3 RNP structure and function; RNA helicases; Polymerase I transcription and processing

Bindra, Ranjit S.

Research Interests:DNA repair; Translational research; Clinical trials with experimental therapeutics; High-throughput drug screening

Clinical Interests:pediatric tumors; central nervous system tumors.

Bond, James E

Clinical Interests:Stereotactic Radiation Therapy

Brash, Douglas E

Research Interests:Ultraviolet Light; Skin Cancer

Cardinale, Francis S.

Research Interests:Randomized double blinded study of Samarium-153 for Hormone Refractory Prostate Carcinoma- Burley Laboratories sponsored study. Efficacy of Three Day/Week Amifostine in Head and Neck Cancer

Clinical Interests:Central nervous system, Head and Neck, Stereotactic Cranial and Body Radiosurgery.

Cardinale, Joseph G.

Clinical Interests:prostate cancer

Carlson, David Joel

Research Interests:Biological optimization of treatment planning; Tumor hypoxia and reoxygenation effects; Heavy ion radiotherapy; Functional imaging; DNA damage and repair; Motion management; 4D imaging and treatment strategies; Prostate cancer; Lung cancer

Clinical Interests:Biologically Guided Radiation Therapy (BGRT); Proton and Carbon Ion Radiotherapy; Stereotactic Body Radiation Therapy (SBRT); Stereotactic Radiosurgery (SRS); Intensity Modulated Radiation Therapy (IMRT); Image Guided Radiation Therapy (IGRT); Total Body Irradiation (TBI); High-dose rate (HDR) brachytherapy

Chang, Bryan William

Research Interests:Combined modality treatment; Stereotactic body radiotherapy (SBRT); Intensity modulated radiation therapy (IMRT); Molecular markers of tumor response and prognosis

Clinical Interests:Gastrointestinal cancers, including esophageal, gastric, pancreatic, hepatic, rectal, and anal cancers; head and neck cancer; lung cancer; stereotactic body radiotherapy (SBRT) for tumors of the chest and abdomen; intensity modulated radiation therapy (IMRT).

Chen, Zhe (Jay)

Research Interests:Theoretical and experimental radiation dosimetry; Radiobiological analysis; Modeling for radiation therapy treatment optimization and outcome analysis; Image-guidance for tumor identification; Treatment design; Delivery verification; Treatment response evaluation in personalized adaptive radiation therapy

Clinical Interests:To provide the best clinical physics support to all aspects of radiation oncology including intensity modulated radiation therapy (IMRT); image guided radiation therapy (IGRT); total skin electron therapy (TSET); total body irradiation (TBI), stereotactic body radiosurgery (SBRT); and radiation therapy plan optimization and treatment evaluation.

Chiang, Veronica L.S.

Research Interests:Brain Tumor; Cancer; Cerebral Metastases; Clinical Outcomes; Radiation Side Effects; Radiosurgery

Clinical Interests:Gamma Knife stereotactic radiosurgery; general neurosurgery; cerebral metastases; brain cancer; pituitary cancer; endocrine cancer; peripheral nerve surgery; stereotactic needle biopsy; management of traumatic brain injury; neurosurgical critical care

Chu, Archie

Research Interests:Adaptive radiation therapy; MRI as therapeutic markers; Image-guided radiation therapy; Highly Diffusion Weighted Tensor imaging;

Clinical Interests:Clinical physics support to all aspects of radiation cancer treatments, and certain procedures are currently and have been practiced: intensity modulated radiation therapy (IMRT); image guided radiation therapy (IGRT); Stereotactic radiosurgery (SRS); High-dose rate (HDR) brachytherapy; Low-dose rate (LDR) brachytherapy; total body irradiation (TBI).

Chung, Joyce Y.

Clinical Interests:breast cancer

Contessa, Joseph N

Research Interests:Adaptive responses of tumor cells to ionizing radiation; Receptor tyrosine kinase signaling; Protein N-linked glycosylation; High throughput screens for novel therapeutic agents; Biologic markers for radiation response

Clinical Interests:Tumors of the Central Nervous System; Gamma Knife Stereotactic Radiotherapy; Brain Metastases; Head and Neck Cancer

Damast, Shari

Research Interests:Women's health; Cancer treatment; Quality of life; Patient-reported outcomes

Clinical Interests:gynecologic cancer; breast cancer; radiation therapy; brachytherapy

Decker, Roy

Research Interests:Lung Cancer; Head & Neck Cancer; Combined Modality Therapy

Clinical Interests:Head & Neck Cancer; Lung Cancer; Stereotactic Body Radiosurgery

Deng, Jun

Research Interests:Image-Guided Radiation Therapy (IGRT); Monte Carlo Treatment Planning for Radiation Therapy of Cancers; Intensity Modulated Radiation Therapy (IMRT); Organ Motion and Deformable Registration; Optimization for Radiation Therapy; Biologically Guided Radiation Therapy (BGRT)

Clinical Interests:Image-Guided Radiation Therapy (IGRT); Kilo-voltage cone beam CT (kVCBCT); Scan optimization and imaging dose reduction; Monte Carlo Treatment Planning (MCTP); Intensity Modulated Radiation Therapy (IMRT); Biologically Conformal Radiation Therapy (BCRT)

DiMaio, Daniel C.

Research Interests:Molecular Biology of Tumor Viruses; Mechanisms of Viral Carcinogenesis; Molecular Basis of Cell Growth Regulation and Senescence; Manipulating Cells and Viruses with Artificial Transmembrane Proteins; Oncogenes; Senescence; Signal Transduction; Trans-membrane Proteins; Tumor Suppressor Genes; Virology; Virus

Evans, Suzanne B.

Research Interests:Breast cancer; Gynecologic cancers; Maximizing therapeutic ratio; Dosimetric prediction and prevention of toxicity; Patient communication

Guo, Fanqing

Research Interests:Quality assurance methods and standards in radiotherapy, especially the IMRT/IGART QA; Treatment planning evaluation standards; Proton and heavier particles therapies and the miniaturization of proton accelerators; Tomotherapy; Application of nano technology in radiotherapy; Application of Monte Carlo in radiotherapy; Comparative radiotherapy between animals and human being

Clinical Interests:Intensity-modulated radiation therapy (IMRT); Image-guided radiation therapy (IGRT); Tomotherapy; Stereotactic radiosurgery; Quality assurance (QA) in radiotherapy; Brachytherapy; Electron beam radiotherapy; Proton and heavier particles therapies. Board Certification: Therapeutic Medical Physics, American Board of Radiology

Higgins, Susan A

Research Interests:General radiation therapy; Radiation techniques; Gynecologic cancer; Cervical cancer; Vulvar cancer; Ovarian cancer; Vaginal cancer; Uterine cancer; Breast cancer; Herbal medicines; Complementary medicine; Gamma knife radiosurgery; Brain metastases; Intracavitary brachytherapy; Interstitial brachytherapy

Clinical Interests:General radiation therapy; breast cancer; early stage breast cancer; locally advanced breast cancer; breast conservation therapy; mammosite radiation therapy; partial breast radiation therapy; intensity modulated radiation therapy (IMRT); radiation techniques; lymphedema; gynecological cancer; brachytherapy; cervix cancer; vaginal cancer; uterine cancer; vulvar cancer; ovarian cancer; intracavitary radiation therapy; interstitial brachytherapy; high dose rate brachytherapy; low dose rate brachytherapy

Husain, Zain A.

Clinical Interests:Head and neck cancer; stereotactic body radiation therapy (SBRT); lung cancer; spine radiosurgery.

Jensen, Ryan B.

Research Interests:Cancer biology; DNA repair; BRCA2; DNA damage signaling; Genomic instability

Johung, Kimberly Lauren

Clinical Interests:Gastrointestinal cancers, including esophageal, gastric, pancreatic, hepatic, rectal, and anal cancers; lung cancer; head and neck cancer; stereotactic body radiotherapy (SBRT) for tumors of the chest and abdomen

Knowlton, Christin A.

Clinical Interests:Experience in 3d conformal external beam radiation therapy; IMRT; IGRT using cone beam imaging; Exposure to Proton Therapy; Tomotherapy; training in SRS; SBRT using linac and Cyberknife platforms; HDR brachytherapy experience for gynecologic; breast; prostate; endobronchial; biliary cancer treatment. Training in LDR brachytherapy including prostate seed implantation and I-125 eye plaques. Work with unsealed parenteral I-125 sources. Training in hyperbaric oxygen therapy.

Lincoln, Holly M.

Research Interests:The use of Image-Guided Radiation Therapy (IGRT) for targeted conformal radiotherapy; Stereotactic Body Radiotherapy (SBRT) and Stereotactic Radiosurgery (SRS); Quality control standards for the safe and effective delivery of radiation therapy.

Clinical Interests:The use of Image-Guided Radiation Therapy (IGRT) for targeted conformal radiotherapy; Stereotactic Body Radiotherapy (SBRT) and Stereotactic Radiosurgery (SRS); Quality control standards for the safe and effective delivery of radiation therapy.

Liu, Wu

Research Interests:Image guided radiotherapy; Tumor motion monitoring and management; Dose reconstruction; Medical image analysis; Ultrasound parametric imaging

Low, K Brooks, Jr

Research Interests:DNA molecule recombination in vivo, relationship of recombination and DNA damage; use of bacteria to diagnose and treat cancer; starvation and mutagenesis

Lu, Yuhong

Research Interests:Hypoxia and Gene Silencing

Mani, Sheida

Research Interests:Study of etiology of esophageal squamous cell carcinoma in Northeastern Iran

Clinical Interests:General radiation therapy; gynecological cancer; vulvar and vaginal carcinoma; endometrial cancer; cervical cancer; gamma knife radiosurgery; trigeminal neuralgia; acoustic neuromas; vestibular schwannomas, Arterio-Venous Malformations (AVM); conformal radiation therapy; central nervous system; Intensity Modulated Radiation Therapy (IMRT); gastrointestinal cancer; esophageal cancer; pancreatic cancer; gastric cancer; rectal cancer; anal cancer; lung cancer; prostate cancer; interstitial brachytherapy; high dose rate brachytherapy

McGibbon, Bruce

Research Interests:Intra-cranial Radiosurgery; Stereotactic Body Radiosurgery; Brain Tumors; Head & Neck Cancer; Breast Cancer

Clinical Interests:Intra-cranial Radiosurgery; Stereotactic Body Radiosurgery; IMRT/IGRT; Calypso System with GPS for the Body; Head & Neck Cancer; Breast Cancer; Brain Tumors; and Prostate Cancer

Moran, Meena Savur

Research Interests:Breast Cancer; Early stage breast cancer; Breast conservation therapy; Prostate cancer; Pelvic malignancies

Clinical Interests:Clinical interest in breast cancer

Nath, Ravinder

Research Interests:Radiation Oncology Physics; Dose calculations; Dosimetry measurements and delivery techniques; Brachytherapy sources and Physics; Radiation devices; Tumor and normal tissue imaging; Radiation Biology

Clinical Interests:Radiation treatment planning, Dose calculation Algorithms, Calibration and Quality Assurance of Radiation Oncology Equipment, Brachytherapy Physics.

Patel, Abhijit A.

Research Interests:Circulating tumor DNA; Next-generation sequencing; RNA profiling; Selection of nucleic acids from combinatorial libraries

Clinical Interests:Prostate Cancer; Lung Cancer; Breast Cancer; Gastrointestinal Cancers; General Radiation Therapy

Pathare, Pradip M.

Research Interests:Image Guided Radiation, Breast Cancer, Prostate Cancer

Clinical Interests:General Radiation Therapy, Image Guided Radiation Therapy, Breast Cancer, Prostate Cancer, Head and Neck Cancer, Lung Cancer

Peschel, Richard E

Research Interests:Intensity modulated radiation therapy; Prostate cancer; Prostate implant; Prostate specific antigen; Radiation therapy

Clinical Interests:General radiation therapy; bladder cancer; testicular cancer; prostate cancer; intensity modulated radiation therapy (IMRT); brachytherapy; lung cancer; lymphoma; breast cancer; melanoma; testes cancer; prostate cancer; renal cancer; eye plaque therapy for choroiadal melanoma.

Roberts, Kenneth B

Research Interests:Cervix cancer and hypoxic cell cytotoxins; Brachytherapy; Pediatric malignancies; Hodgkin's disease; Health services research

Clinical Interests:General radiation therapy; pediatric radiation therapy; hematologic malignancy; lymphoma; Hodgkin’s disease; total body irradiation; endovascular brachytherapy; oncologic brachytherapy; gynecologic cancer; cervix cancer; gastrointestinal cancer; colorectal cancer

Rockwell, Sara

Research Interests:Microenvironmental heterogeneity in solid tumors; Experimental cancer therapy; Biological effects of ionizing radiation; Effects of hypoxia and low pH

Clinical Interests:Collaboration in the design and development of clinical trials resulting from research in our laboratory; participation in the activities of the Yale Center for Clinical Investigation that support clinical and translational research at Yale.

Rogers, Faye A

Research Interests:Breast cancer; Drug design; Altered helical structures; Cancer and genomic instability; DNA repair and apoptosis

Son, Yung H

Research Interests:Therapeutic gain factor with combination of low dose rate radiation and external beam radiation in all sites; Radiation sensitization with chemical modulator in clinical application

Clinical Interests:General radiation therapy; head and neck cancer; definitive or intra-operative brachytherapy; esophageal cancer; colon cancer; lung cancer; soft-tissue sarcoma; skin cancer; pediatric cancer; unknown primary cancer; all invasive low- or high-dose-rate interventional brachytherapy and remote after-loading gamma-Med brachytherapy, particularly in otolaryngology, broncho-pulmonary, abdominal, retro-peritoneal, and colorectal malignancies

Su, Fan-Chi Frances

Research Interests:Four-dimensional radiation therapy; Adaptive radiation therapy; Tumor control and normal tissue possibility evaluation; Outcome-driven treatment planning

Summers, William C

Research Interests:History of molecular biology; Development of target theory; History of Manchurian Plague, 1910-1911

Sung, Patrick

Research Interests:Repair of DNA double-strand breaks; Repair by homologous recombination; Repair by DNA end-joining

Weidhaas, Joanne Barnes

Research Interests:MicroRNAs; Genetics; Radiation and chemotherapy resistance

Clinical Interests:Breast Cancer; Partial Breast Irradiation (PBI); Gynecological Cancer; Cervical Cancer

Yu, James Byunghoon

Research Interests:Genitourinary cancers; Central nervous system cancers; Breast cancer; Head and neck cancer; IMRT; Health outcomes and utilization research

Clinical Interests:Genitourinary cancers; Central Nervous System cancers; prostate brachytherapy; head and neck cancer; lung cancer; breast cancer; radiation oncology

Yun, Zhong

Research Interests:Molecular and cancer biology; Stem cell biology, hypoxia; microRNA, tumor microenvironment; Obesity and metabolic syndromes