Tamas L. Horvath DVM, PhD

Jean and David W. Wallace Professor of Comparative Medicine and Professor of Neurobiology and of Obstetrics, Gynecology, and Reproductive Sciences; Chair, Section of Comparative Medicine; Jean and David W. Wallace Professor of Biomedical Research, Director, Yale Program in Integrative Cell Signaling and Neurobiology of Metabolism

Departments & Organizations

Biological and Biomedical Sciences (BBS): Neuroscience

Interdepartmental Neuroscience Program

Comparative Medicine: Integrative Cell Signaling & Neurobiology of Metabolism (ICSNM)

Neurobiology: Kavli Institute for Neuroscience

Diabetes Endocrinology Research Center

Obstetrics, Gynecology & Reproductive Sciences: Reproductive Neurosciences Group


Research Interests

Neurobiology of obesity; Neuroendocrine physiology more...


Education

  • D.V.M., University of Veterinary Sciences, Budapest, 1990
  • Ph.D., Jozsef Attila University of Sciences, 1998

Selected Publications

  • Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity. Diano S, Liu ZW, Jeong JK, Dietrich MO, Ruan HB, Kim E, Suyama S, Kelly K, Gyengesi E, Arbiser JL, Belsham DD, Sarruf DA, Schwartz MW, Bennett AM, Shanabrough M, Mobbs CV, Yang X, Gao XB, Horvath TL. Nat Med. 2011 Aug 28;17(9):1121-7. doi: 10.1038/nm.2421.
  • Dietrich MO, Antunes C, Geliang G, Liu Z-W, Borok E, Nie Y, Xu AW, Souza DO, Gao Q, Diano S, Gao X-B, Horvath TL (2010) AgRP neurons mediate Sirt1’s action on the melanocortin system and energy balance: roles for SirT1 in neuronal firing and synaptic plasticity. J Neurosci 2010 Sep 1;30(35):11815-25.
  • Horvath TL, Sarman B, García-Cáceres C, Enriori PJ, Shanabrough M, Borok E, Argente J, Chowen JA, Perez-Tilve D, Pfluger PT, Brönneke HS, Levin BE, Diano S, Cowley MA, Tschöp MH (2010) Synaptic Input Organization of the Melanocortin System Predicts Diet-Induced Hypothalamic Reactive Gliosis and Obesity. PNAS 2010 Aug 17;107(33):14875-80. Epub 2010 Aug 2.

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