Susan Kaech PhD

Associate Professor of Immunobiology; HHMI Early Career Scientist

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Immunology | Microbiology

Office of Student ResearchInfectious DiseasesMolecular VirologyImmunobiology: Lymphocyte Development; HTIMolecular Virology

Research Interests

Mechanisms of memory T cell development; Developmental Biology; Immunobiology; Immunology; Vaccine; Immunobiology; T-Cells; Vaccines; Adaptive immunity and immunological memory to viruses more...


  • B.S., University of Washington, Seattle, WA, 1993
  • Ph.D., Stanford University, 1998

Selected Publications

  • Staron M, Gray S, Li MO, Ip WK, Kaech SM. FoxO1 directly regulates the expression of PD-1 and sustains viral specific CD8+ T-cell responses during chronic infection. Immunity 41(5) 802-14 (2014). PMCID in Progress
  • Laidlaw BJ, Zhang N, Craft J, Kaech SM. CD4 T cells required for development and function of tissue resident memory CD8 T cells through a T-bet-dependent mechanism. Immunity 41(4):633-45 (2014). PMCID in Progress.
  • Ho PC, Meeth KM, Tsui YC, Srivastava B, Bosenberg MW, Kaech SM. Immune-based antitumor effects of BRAF Inhibitors rely on signaling by CD40L and IFN-?. Cancer Res, 74(12):3205-17 (2014). PMCID: PMC4063281.



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