Susan Kaech PhD

Associate Professor of Immunobiology; HHMI Early Career Scientist

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Immunology | MicrobiologyInfectious Diseases

Molecular Virology

Immunobiology: Lymphocyte Development | HTI

Molecular Virology

Research Interests

Mechanisms of memory T cell development; Developmental Biology; Immunobiology; Immunology; Vaccine; Immunobiology; T-Cells; Vaccines; Adaptive immunity and immunological memory to viruses more...


  • B.S., University of Washington, Seattle, WA, 1993
  • Ph.D., Stanford University, 1998

Selected Publications

  • Cui W, Liu Y, Weinstein JS, Craft J & Kaech SM. An IL-21/IL-10/STAT3 pathway is critical for functional maturation of memory CD8+ T cells. Immunity 35:792-805 (2011). PMCID in progress.
  • Marshall HD, Chandele A, Jung YW, Meng H, Poholek AC, Parish IA, Rustishauser R, Cui W, Kleinstein SH, Craft J and Kaech SM. Differential Expression of Ly6C and T-bet Distinguish Effector and Memory Th1 CD4(+) Cell Properties during Viral Infection. Immunity 35:633-46 (2011). PMCID in process.
  • Joshi NS, Cui W, Dominguez CX, Chen JH, Hand TW and Kaech SM. Increased numbers of pre-existing memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells. J Immunol 187(8):4068-76 (2011). PMCID in process.



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