Stefan Somlo MD

C. N. H. Long Professor of Medicine (Nephrology) and Professor of Genetics; Chief, Section of Nephrology

Departments & Organizations

Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development: Genetics and Genomics | Molecular Medicine, Pharmacology, and Physiology

Yale Medical Group

Physiology of Human Disease

Graduate Program in Cellular and Molecular Physiology

Internal Medicine: Nephrology

Genetics

Research Interests

Genetic kidney and liver disease; Cilia function in tissue homeostasis; Polycystin function more...

Education

• B.A., Harvard University, 1980
• M.D., Columbia University, 1984

Selected Publications

• Fedeles SV, Tian X, Gallagher AR, Mitobe M, Nishio S, Lee SH, Cai Y, Geng L, Crews CM, Somlo S: A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation. Nat Genet 43:639-647, 2011
• Nishio S, Tian X, Gallagher AR, Yu Z, Patel V, Igarashi P, Somlo S: Loss of oriented cell division does not initiate cyst formation. J Am Soc Nephrol 21:295-302, 2010
• Geng L, Boehmerle W, Maeda Y, Okuhara DY, Tian X, Yu Z, Choe CU, Anyatonwu GI, Ehrlich BE, Somlo S: Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2. Proc Natl Acad Sci U S A 105:15920-15925, 2008

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