Ronald A. Albright PhD

Associate Research Scientist in Pathology; Associate Research Scientist/S

Research Interests

x-ray crystallography; protein structure/function


Selected Publications

  • Blood. 2012 Nov 22;120(22):4432-4440. Albright RA, Chang WC, Robert D, Ornstein DL, Cao W, Liu L, Redick ME, Young JI, De La Cruz EM, Braddock DT. NPP4 is a procoagulant enzyme on the vascular endothelium.
  • J. Biol. Chem. 2011 Aug 26;286(34):30130-41. Saunders LP, Cao W, Chang WC, Albright RA, Braddock DT, De La Cruz EM. Kinetic analysis of Autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution.
  • J Biol Chem. 2007 Nov 30;282(48):35046-55. Epub 2007 Oct 10. Albright RA, Joh K, Morais-Cabral JH. Probing the structure of the dimeric KtrB membrane protein.
  • Cell. 2006 Sep 22;126(6):1147-59. Albright RA, Ibar JL, Kim CU, Gruner SM, Morais-Cabral JH. The RCK domain of the KtrAB K+ transporter: multiple conformations of an octameric ring.
  • Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3431-6. Albright RA, Matthews BW. How Cro and lambda-repressor distinguish between operators: the structural basis underlying a genetic switch.
  • J Mol Biol. 1998 Jul 3;280(1):137-51. Albright RA, Matthews BW. Crystal structure of lambda-Cro bound to a consensus operator at 3.0 A resolution.
  • Protein Sci. 1998 Jul;7(7):1485-94. Albright RA, Mossing MC, Matthews BW. Crystal structure of an engineered Cro monomer bound nonspecifically to DNA: possible implications for nonspecific binding by the wild-type protein.
  • Biochemistry. 1996 Jan 23;35(3):735-42. Albright RA, Mossing MC, Matthews BW. High-resolution structure of an engineered Cro monomer shows changes in conformation relative to the native dimer.
  • Biochemistry. 1996 Jan 23;35(3):743-8. Mollah AK, Aleman MA, Albright RA, Mossing MC. Core packing defects in an engineered Cro monomer corrected by combinatorial mutagenesis.

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