Pharmacology Faculty

       

Anderson, Karen S

Research Interests: Enzyme function; Anti-viral agents

Bennett, Anton M.

Research Interests: Signal transduction; Protein tyrosine phosphatases; Cancer; Diabetes; Obesity; Muscle stem cells; Muscular dystrophy

Boggon, Titus

Research Interests: Structural biology of signal transduction

Calderwood, David A.

Research Interests: Integrin; Cell adhesion; Cell migration; Cytoskeleton; Structural biology

Cheng, Yung-Chi

Research Interests: Cancer; Viral chemotherapy; Chinese herbs; Chinese medicine

Cooper, Jack R.

Research Interests: Neuropharmacology

Crews, Craig M

Research Interests: Limb regeneration; wound epidermis; blastema; natural product mode of action studies; angiogenesis; Wnt signaling; protein turnover; protein kinase regulation

Dannies, Priscilla Shaw

Research Interests: Endocrinology

DiGiovanna, Michael P

Research Interests: Breast cancer; HER-2/neu/ErbB-2; IGF1 receptor; EGF receptor; Growth factor receptor tyrosine protein kinases in malignancy; Estrogen receptor; Signal transduction; Breast cancer clinical trials

Clinical Interests: Breast Cancer

Ehrlich, Barbara E

Research Interests: Intracellular calcium regulation

Eswarakumar, V. P.

Research Interests: Fibroblast Growth Factor Receptors (FGFRs)

Ha, Ya

Research Interests: Membrane protein; X-ray crystallography; Enzyme mechanism

Hodsdon, Michael Edwin

Research Interests: Biochemistry; Biophysics; Breast Cancer; Clinical Chemistry; Drug Metabolism; Health and Medicine; Laboratory Practice or Procedure; Nuclear Magnetic Resonance; Pathobiology; Pharmacology; Spectroscopy; Structural Biology; Toxicology

Clinical Interests: Clinical chemistry; toxicology and testing for drugs of abuse; therapeutic drug monitoring; tandem mass spectrometry; protein analysis for detection of multiple myeloma

Howe, James R

Research Interests: Glutamate receptors

Jordt, Sven-Eric

Research Interests: Sense of touch and pain in humans and animals; Chemosensory processes in sensory neurons and their role in chemical environmental exposures; Neural sensitization in asthma; Hypersensitivity disorders

Kaczmarek, Leonard Konrad

Research Interests: Neuroscience; Learning and memory; Ion channels

Lolis, Elias

Research Interests: Cancer; Inflammation; Infectious disease; Macromolecular X-ray crystallography; Signaling pathways; Drug design; High throughput screening (HTPS)

Nairn, Angus Clark

Research Interests: Dopaminergic signal transduction; Structure and function of protein kinases and phosphatases

Paintsil, Elijah

Research Interests: HIV translational research; Cellular pharmacology of HIV-RT inhibitors in relation to clinical toxicities; Fitness and evolution of HIV drug resistant mutants; Molecular epidemiology and dynamics of HIV/HCV transmission

Clinical Interests: Pediatric infectious diseases; pediatric HIV/AIDS - special interest in management of multi-drug-resistant HIV infection and management of pediatric HIV in resource-limited countries; and pediatric community acquired Methicillin-resistant Staphylococcus aureus (MRSA) infections.

Picciotto, Marina

Research Interests: Neuroscience; Molecular basis of behavior; Intracellular signaling; Mouse genetic models

Rockwell, Sara

Research Interests: Microenvironmental heterogeneity in solid tumors; Experimental cancer therapy; Biological effects of ionizing radiation; Effects of hypoxia and low pH

Clinical Interests: Collaboration in the design and development of clinical trials resulting from research in our laboratory; participation in the activities of the Yale Center for Clinical Investigation that support clinical and translational research at Yale.

Rudnick, Gary

Research Interests: Neurotransmitter recycling; Mechanism of membrane transport

Sartorelli, Alan Clayton

Research Interests: Cancer research; Drug development; Drug resistance

Schlessinger, Joseph

Research Interests: Growth factor receptors; Intracellular signaling pathways; Protein kinases; Phosphorylation; SH2, SH3 and other protein modules involved in signal transduction; Drug discovery

Sessa, William C.

Research Interests: Vascular endothelium and inflammation; MiRNAs; Vascular development and angiogenesis; Lipid domains and signaling; Atherosclerosis

Turk, Benjamin E

Research Interests: Cell signaling; Protein kinases; Chemical biology; Proteomics; Metalloproteases; Protein engineering

Waxman, Stephen George

Research Interests: Axons; Electrophysiology; Genes; Ion Channels; Molecular Biology; Multiple Sclerosis; Pain Syndromes; Sodium Channels; Spinal Cord Injury; Stroke

Wu, Dianqing (Dan)

Research Interests: Wnt; signal transduction; G protein, Chemotaxis;Cell migration; Cancer biology and therapeutics; Stem cell biology; Chemoattractant signaling; Inflammation