Peter James Krause MD

Senior Research Scientist in Epidemiology (Microbial Diseases), in Medicine (Infectious Diseases) and in Pediatrics (Infectious Disease) and Lecturer in Epidemiology (Microbial Diseases)

Research Interests

Vector borne diseases


Research Summary

Dr. Krause’s research interests are in vector borne diseases including babesiosis, Lyme disease and Borrelia miyamotoi, a relapsing fever spirochete. Current projects include babesiosis and Lyme disease persistence, co-infection, and geographic expansion; the host immunologic response to Babesia microti; prevention of transmission of babesiosis through blood transfusion; and human infection with Borrelia miyamotoi.

Extensive Research Description

Dr. Krause’s research interests are in vector borne diseases including babesiosis, Lyme disease and Borrelia miyamotoi, a relapsing fever spirochete. Current projects include babesiosis and Lyme disease persistence, co-infection, and geographic expansion; the host immunologic response to Babesia microti; prevention of transmission of babesiosis through blood transfusion; and human infection with Borrelia miyamotoi.


Selected Publications

  • Vannier E and Krause PJ. Human Babesiosis. New Engl J Med 2012;366:2397-407.
  • Platonov AE, Karan LS, Kolyasnikova NM, Makhneva NA, Toporkova MG, Maleev VV, Fish D, Krause PJ. Human Infection with the relapsing fever spirochete Borrelia miyamotoi. Emerg Inf Dis, 2011,17:1816-1823.
  • Wormser GP, Prasad A, Neuhaus E, Joshi S, Nowakowski J, Nelson J, Mittleman A, Aguero-Rosenfeld M, Topal J, Krause PJ. Emergence of Resistance to Azithromycin-Atovaquone in Immunocompromised Patients with Babesia microti Infection. Clin Inf Dis, 50:381-386, 2010
  • Young C and Krause PJ. The problem of transfusion transmitted babesiosis. Transfusion, 2009:49:2548-2550.
  • Vannier E, Gewurtz B, Krause PJ. Human babesiosis. Infectious Diseases Clinics of North America, 22:469-88, 2008.
  • Krause PJ, Gewurz BE, Hill D, et al. A. Persistent and relapsing babesiosis in immunocompromised patients. Clinical Infectious Diseases, 46:370-376, 2008.
  • Krause PJ, Daily J, Telford SR, Vannier E, Lantos P, Spielman A. Shared features in the pathobiology of babesiosis and malaria. Trends in Parasitology 23:605-610, 2007.
  • Krause PJ, Foley DT, Burke GS, et al. Reinfection and relapse in early Lyme disease. American Journal of Tropical Medicine and Hygiene 75: 1090-1094, 2006
  • Burke G, Wikel SK, Spielman A, Telford SR, McKay K, and Krause PJ. Hypersensitivity to ticks and Lyme disease risk, Emerging Infectious Diseases 11:36-41, 2005.
  • Krause PJ, McKay K, Gadbaw J, et al: Increasing health burden of human babesiosis in endemic sites. American Journal of Tropical Medicine and Hygiene 68:431-436, 2003.

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