Obstetrics, Gynecology & Reproductive Sciences Faculty
Research Interests:Homeobox genes; Embryo implantation; Endometriosis; Stem cells; Menopause; uterine Development; Endocrine disruption; Developmental programming
Clinical Interests:Infertility; In Vitro Fertilization (IVF); Reproductive surgery; Congenital anomalies; Diethylstilbesterol (DES) exposure; Implantation/endometrial receptivity; Endometriosis; Menopause; Polycystic Ovarian Syndrome (PCOS); Recurrent pregnancy loss (1st trimester); Fibroids
Clinical Interests:Maternal and fetal inflammation/ infection; pregnancy complications; chorioamnionitis; preterm birth; free radical formation; critical care; sepsis; systemic inflammatory response syndromes; renal injury in the critically ill; multiple organ dysfunction syndrome
Research Interests:Reproductive Immunology; Immunology of Pregnancy
Clinical Interests:Infertility; Egg donation; Recurrent pregnancy loss (1st trimester); Congenital anomalies; Endometriosis; Menstrual problems; Menopause
Research Interests:translational research; clinical research; gynecologic cancer
Clinical Interests:Pre-malignant and malignant gynecologic disorders involving the vulva, cervix, vagina, uterus, ovaries, and placenta, with emphasis on minimally invasive approaches for gynecologic cancer, including laparoscopic staging, radical vaginal surgeries, and radical tracheolectomy for treatment of cervical cancer with preservation of childbearing capacity; Robotic surgery; Chemotherapy for all gynecologic cancers
Research Interests:Fetal heart function; Congenital heart defects; Monochorionic pregnancy; Fetal anomalies
Clinical Interests:Congenital heart defect; Fetal echocardiogram; Fetal therapy; Twin-to-twin transfusion syndrome (TTTS); Multiple pregnancies; Fetal laser surgery
Research Interests:Pelvic organ prolapse; Vaginal Mesh; Fecal Incontinence and neuromodulation
Clinical Interests:Urinary and fecal incontinence; Pelvic organ prolapse; Pelvic floor disorders; Interstitial cystitis; Urodynamic testing office; Cystoscopy; Collagen injections; Biofeedback for urinary and fecal incontinence; Advanced laparoscopic surgery; Abdominal and pelvic floor reconstruction; Vaginal hysterectomy for the enlarged/ fibroid uterus; Vaginal fistulae; Minimally invasive surgery for prolapse and incontinence; robotic surgery.
Research Interests:Cervical ripening and preterm labor; intraamniotic infection; fetal growth restriction; epidemiological trends in obstetrics
Clinical Interests:preconception counseling; medical complications of pregnancy; prenatal diagnosis; amniocentesis; multifetal pregnancies; fetal growth restriction; preeclampsia; infectious disease in pregnancy; preterm labor; intrapartum care; postpartum care
Research Interests:Prenatal diagnosis; Fetal therapy; Chorionic villus sampling; Cordocentesis
Clinical Interests:Fetal treatment; Fetal echocardiography; Chorionic villus sampling (CVS); Fetal surgery; Amniocentesis; First trimester screening
Research Interests:Metabolism Regulation
Clinical Interests:Prenatal diagnosis; Obstetrical and pelvic ultrasound; Treatment of medical complications of pregnancy
Research Interests:Neurotransmission; Neurotransmitter response and synaptic plasticity; Cellular physiology of neuropeptides (hypocretin/orexin, melanin concentrating hormone, neuropeptide Y, ghrelin, leptin, and a-MSH); Ion channels (Na+, Ca2+, K+ channels); Electrophysiology/patch clamp recording; calcium imaging; Hypothalamus/lateral hypothalamic area; Energy homeostasis/feeding regulation; Sleep homeostasis and regulation; Drug addiction
Research Interests:Decision analysis and modeling of female sterilization procedures; patient-centered outcomes; digoxin; post-abortal contraception
Clinical Interests:Family planning; contraception; birth control; sterilization; tubal ligation; Essure. Pregnancy termination; abortion. Complex contraception consultation for women with co-morbidities (transplants, stroke, MI, bariatric surgery, clotting disorders). Medical or surgical management of early pregnancy failures (<12 weeks). Surgical management of intrauterine fetal demise.
Clinical Interests:Counseling of individuals and couples in all phases of reproduction and pregnancy regarding the emotional impact of infertility, pregnancy loss, and multi-fetal pregnancies; ethical and psychological aspects of egg and sperm donation; gestational surrogacy
Clinical Interests:Diagnostic and treatment modalities for: Urinary incontinence; Pelvic organ prolapse; Pelvic floor disorders; Interstitial cystitis; Reconstructive pelvic surgery; Advanced laparoscopy; Minimally invasive surgery; Treatment of simple and complex urogenital fistulae; Office cystoscopy; Non surgical treatment options including: Multi-channel urodynamic testing, Behavioral education and therapy; Pelvic floor-muscle rehabilitation; Physiotherapy and biofeedback; Myofascial release
Research Interests:Placental physiology; intrauterine growth restriction; preeclampsia; adverse pregnancy outcomes
Clinical Interests:Dr. Guller directs the Yale Gyn/Endocrine Laboratory which uses Immulite technology to analyze hormone levels in serum from patients seen in the Division of Reproductive Endocrinology and Infertility.
Clinical Interests:Diabetes in pregnancy; Endocrine disorders in pregnancy; Obesity in pregnancy; Immune disorders in pregnancy; Preeclampsia; In-utero fetal programming; Ultrasound
Research Interests:Steroid biochemistry; Steroid receptors; Synthesis of estrogens; locally active estrogens; SERMs; Radiochemistry; Estrogens and Androgens labeled with high energy isotopes
Research Interests:Neurobiology of obesity; Neuroendocrine physiology
Clinical Interests:Neurodegenerative diseases; aging; diet; nutrition
Research Interests:RNA biology; Stem cells; Post-transcriptional regulation of gene expression; Cancer biology
Clinical Interests:Sperm function tests; sperm structure; donor insemination; sperm cryopreservation (freezing) prior to vasectomy or oncological treatment; In Vitro Fertilization (IVF)
Research Interests:Obstetric Intervention; group B streptococcus
Clinical Interests:evaluating the feasibility and need for a low intervention birth setting for low risk mothers
Research Interests:Endometrium; placenta; infertility; pregnancy complications; autism
Clinical Interests:infertility; endometrial function tests; recurrent pregnancy loss; placental pathology
Research Interests:Polycystic ovary syndrome; Endometrial angiogenesis; Oxidative stress and endothelial dysfunction
Clinical Interests:Infertility; Polycystic ovary syndrome; Premature ovarian failure; Asherman's syndrome; Abnormal uterine bleeding; Reproductive surgery; Recurrent pregnancy loss
Research Interests:Endometrial hemostasis; Angiogenesis; Endometrial immune response; Endometriosis.
Clinical Interests:- infertility treatment - polycystic ovarian syndrome - recurrent pregnancy loss
Research Interests:Genetics of reproductive disorders; Cell signaling of the Follicle Stimulating Hormone; Receptor Mutation analysis of patients with abnormal folliculogenesis and oogenesis; Preimplantation genetic diagnosis
Research Interests:Positive gonadal hormonal negative bisphenol A
Research Interests:epidemiology; outcomes research
Clinical Interests:high risk pregnancy; preterm labor; multiple gestations; ultrasound; labor and birth; critical care obstetrics; obesity
Research Interests:obstetric care delivery; cognitive behavioral therapy; complications of pregnancy; centering pregnancy
Clinical Interests:Prenatal diagnosis; Treatment of medical complications of pregnancy; global and international healthcare initiatives.
Research Interests:Cancer; Women's cancers; Diagnostics; Theragnostics; Biotherapeutics; Precision/personalized medicine, signal transduction; EGFR/ERBB/HER-driven adult solid tumors
Clinical Interests:1)Discovery and application of disruptive innovations to improve the detection, treatment, and prevention of cancer.
2) ‘Precision medicine’ in oncology -- the coupling of early detection and theragnostic biomarkers with the treatment of patients using biologically-targeted therapeutics.
3) Use of “soluble” EGFR/HER receptors (sEGFR and sHERs) as novel serum/tissue biomarkers and also as potential biotherapeutics for the treatment of adult solid tumors.
Research Interests:Embryogenesis; epigenetic regulation of placental development; role of Pumilio, RNA binding protein in oogenesis and embryogenesis; trophoblast stem cells
Clinical Interests:Infertility; Polycystic Ovarian Syndrome and recurrent pregnancy loss.
Clinical Interests:Infertility; fertility preservation for cancer patients; PCOS.
Research Interests:Immunology of Gynecologic tumors; Immunology of Implantation; Ovarian Cancer Stem Cells
Clinical Interests:1) Ovarian Cancer 2) Infection and pregnancy
Research Interests:Fetal loss; Preeclampsia; Fetal growth restriction; Preterm delivery; Abruption; Thromboembolism; Postpartum hemorrhage; Inherited and acquired thrombophilia; Antithrombin deficiency; Autoimmune disorders Alloimmune thrombocytopenia; Platelet disorders; Women’s health following pregnancy complications.
Clinical Interests:Fetal loss; recurrent miscarriage; stillbirth Preeclampsia; Fetal growth restriction; Preterm delivery; Abruption; Thromboembolism; Postpartum hemorrhage; Inherited and acquired thrombophilia; Antithrombin deficiency; Factor V Leiden; Autoimmune disorders Alloimmune thrombocytopenia; Platelet disorders; Women’s health following pregnancy complications; Thrombosis and bleeding disorders; Invasive fetal therapy; Fetal Blood Sampling (FBS); Chorionic villous sampling; Prenatal diagnosis; First trimester screening; Doppler ultrasound
Research Interests:Ovarian reserve: decline in ovarian reserve and multisystem implications thereof; Polycystic Ovarian Syndrome (PCOS) and metabolic implications; menopause; Vitamin D and Reproductive Function
Clinical Interests:Infertility; Polycystic Ovarian Syndrome (PCOS); Menopause/perimenopause; Diminished ovarian reserve; Obesity related reproductive dysfunction; Osteoporosis/osteopenia/low bone mineral density; Menstrual disturbances, Fibroids, PMDD.
Research Interests:Fertility and Infertility; Cryopreservation; Oocyte biology; Embryonic competence
Clinical Interests:Infertility (female and male) In Vitro Fertilization (IVF); Intracytoplasmic Sperm Injection (ICSI); Pre-implantation Genetic Diagnosis (PGD); Egg donation and gestational surrogacy fertility; Fertility Preservation for women and men with cancer: Egg/embryo freezing and sperm banking; Reproductive surgery; Genetics of infertility; Infertile men with vasectomy; Failed vasectomy or absence of the vas deferens; Percutaneous Epididymal Sperm Aspiration (PESA); Testicular Sperm Extraction (TESE)
Research Interests:Patient Safety; Induction of labor; Management of labor and delivery; Intra-amniotic infection and inflammation; Clinical trials and clinical research design
Clinical Interests:High-risk pregnancies; Prenatal diagnosis; Labor and delivery; Patient Safety; Obesity
Research Interests:ovarian cancer; cancer genetics; cancer prophylaxis; micro RNA; sexuality
Clinical Interests:ovarian cancer; uterine cancer; cervical cancer; cancer prevention; cancer prophylaxis; genetic risk factors; sexuality; menopause; early cancer detection
Clinical Interests:Pelvic muscle floor rehabilitation or training; electrical stimulation; behavioral modification; frequent urinary tract infection; urinary frequency and urgency; pessary fitting; urodynamic studies; cystoscopy; rectocele; cystocele sexual dysfunction
Research Interests:Minimally invasive surgical techniques; Ovarian stem cell research; Micro-RNA; Novel biologic agents for treatment; Early detection of ovarian cancer
Clinical Interests:Ovarian; uterine; vaginal; cervical and vulvar cancer; Difficult gynecologic surgery; Trophoblastic neoplasia; Unknown primary cancer; Brachytherapy; Gestational trophoblastic neoplasia
Research Interests:Mutational landscape of gynecolocic tumors; Therapeutic vaccine development for gynecologic malignancies; Tumor immunology; Immunotherapy; Tumor angiogenesis; Radiation biology; Experimental therapeutics in gynecologic oncology
Clinical Interests:Cancer of the ovary, uterus, vagina, cervix and vulva; Intraperitoneal chemotherapy; Tumor immunology and immunotherapy; Tumor angiogenesis; Radiation biology; Experimental therapeutics in Gynecologic Oncology
Research Interests:Ovarian Cancer, uterine, vaginal, cervical and vulvar cancer. Screening for ovarian cancer.
Clinical Interests:Ovarian, uterine, vaginal, cervical and vulvar cancer; Difficult gynecologic surgery; Screening for ovarian cancer; Gestational neoplasia; Brachytherapy
Research Interests:Translational regulation of gene expression during oocyte end early embryo development. Assessment of embryo viability in assisted reproductive technologies. Pathogenesis of endomentriosis.
Clinical Interests:Oocyte donation and surrogacy; infertility; In Vitro Fertilization (IVF); reproductive surgery; advanced endoscopic surgery; reproductive options for women with cancer; endometriosis; menstrual disorders; dysfunctional uterine bleeding; polycystic ovarian syndrome; hirsutism; recurrent pregnancy loss (1st trimester); menopause; premature ovarian failure
Clinical Interests:Preterm birth prediction; Preterm birth prevention and treatment; Prenatal diagnosis; Family Planning; Gynecologic ultrasound
Clinical Interests:Gynecologic cancers (ovarian, uterine, cervical, vulvar, and vaginal cancers); Gestational trophoblastic neoplasia; Complicated laparoscopic surgery; Robotic surgery; Single-port laparoscopic surgery; Advanced and complicated pelvic surgery; Chemotherapy for gynecologic cancers
Clinical Interests:high-risk maternity;
Research Interests:Environmental physiology; Reproductive hormone effects on temperature and body fluid regulation; Polycystic Ovary Syndrome; Orthostatic tolerance; Blood pressure regulation
Research Interests:Contraceptive care and access.
Clinical Interests:Family Planning; Long-acting reversible contraception (LARC, intrauterine devices, implants), Medically Complex Contraception; Teen Reproductive Health.