Melissa Langhan MD, MHS

Associate Professor of Pediatrics (Emergency Medicine); Fellowship Director, Pediatric Emergency Medicine; Director of Education, Pediatric Emergency Medicine

Research Interests

Pediatric Emergency Medicine; End-tidal carbon dioxide monitoring; Capnography; Acute exacerbations of asthma; Prehospital care; Patient safety; Objective measures of severity

Current Projects

  • Can end-tidal carbon dioxide monitoring reduce the frequency of hypoxia during moderate sedation with ketamine in children?
  • Identifying the barriers and facilitators to the implementation of new technology in acute care areas
  • A qualitative study regarding providers perceptions on capnography use during moderate sedation
  • Evaluating trainees' ability to normally ventilate children via bag-valve mask ventilation through capnography
  • Assessing the use of capnography during critical events in the Emergency Department

Research Summary

Dr. Langhan is interested in performing research to improve the safety of acutely ill children and develop objective measurements of illness.

Extensive Research Description

I plan to devote my academic career to applying new, noninvasive technologies to the clinical problems seen acutely in children by designing and executing carefully planned patient-oriented research. During the past several years I have been able to successfully complete several research projects using new technologies in the pediatric emergency department such as capnography and portable spirometry. Furthermore, I have been able to document that capnography is not being utilized to its full potential in both the emergency and critical care settings. My goal is to continue patient oriented research using noninvasive technologies that provide us with objective patient assessment and can be used to make timely clinical decisions, improve patient safety and reduce medical costs.

Selected Publications

  • Thornton M, Langhan ML, Chen L. Neonatal Seizures: Soothing a Burning Topic. Pediatric Emergency Care. 2013; 29(10): 1107-1110.
  • Becker H, Langhan M. Capnography in the Pediatric Emergency Department: Clinical Applications. Pediatric Emergency Medicine Practice 2013; 10(6): 1-26.
  • Tiyyagura G, Arnold L, Cone D, Langhan M. Pediatric Anaphylaxis in the prehospital setting. Prehospital Emergency Care, 2014 Jan-Mar;18(1):46-51.
  • Langhan ML. Acute Alcohol Intoxication in Adolescents: Frequency of Respiratory Depression. The Journal of Emergency Medicine, 2013; 44(6): 1063-9.
  • Langhan ML, Mallory M, Hertzog J, Lowrie L, Cravero JP. Physiologic Monitoring Practices during Pediatric Procedural Sedation: A Report from the Pediatric Sedation Research Consortium. Archives of Pediatrics and Adolescent Medicine. In press. Epub Sept 10, 2012.
  • Langhan ML, Auerbach M, Smith A, Chen L. Improving Detection of Endotracheal Tube Dislodgement by Pediatric Residents with Capnography: A Randomized Controlled Trial. Journal of Pediatrics, 2012; 160(6): 1009-1014.
  • Riera A, Hsiao A, Langhan ML, Goodman R, Chen L. Diagnosis of Intussusception by Physician Novice Sonographers in the Emergency Department. Annals of Emergency Medicine, 2012; 60(3):264-8.
  • Langhan ML, Ching K, Northrup V, Alletag M, Kadia P, Santucci K, Chen L. A Randomized Controlled Trial of Capnography in the Correction of Simulated Endotracheal Tube Dislodgement. Academic Emergency Medicine. 2011; 18(6): 590-6.
  • Riera A, Langhan M, Northrup V, Santucci K, Chen L. Remember the saphenous: ultrasound evaluation and intravenous site selection of peripheral veins in young children. Pediatric Emergency Care. 2011; 27(12):1121-5.
  • Langhan ML, Chen L, Marshall C, Santucci KA. Detection of Hypoventilation by Capnography and its Association with Hypoxia in Children Undergoing Sedation with Ketamine. Pediatric Emergency Care 2011; 27(5): 394-7.


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