Molecular Biophysics and Biochemistry Faculty

Baserga, Susan

Research Interests:Ribosome biogenesis; rRNA processing; U3 RNP structure and function; RNA helicases; Polymerase I transcription and processing

Biederer, Thomas

Research Interests:Biochemistry of membrane proteins; molecular and cellular neuroscience; synapse formation

Brudvig, Gary

Research Interests:photosystem II; EPR spectroscopy; metalloproteins; artificial photosynthesis

Crothers, Donald

Research Interests:DNA bending; RNA conformation; RNA-protein interactions; characterization of DNA-drug interactions

De La Cruz, Enrique

Research Interests:Cytoskeleton; RNA helicases; Kinetics; Thermodynamics; Polymer Mechanics; Processivity

DiMaio, Daniel

Research Interests:Molecular Biology of Tumor Viruses; Mechanisms of Viral Carcinogenesis; Molecular Basis of Cell Growth Regulation and Senescence; Manipulating Cells and Viruses with Artificial Transmembrane Proteins; Oncogenes; Senescence ; Signal Transduction; Trans-membrane Proteins; Tumor Suppressor Genes; Virology; Virus

Engelman, Donald

Research Interests:Helix Interactions; Lipid Bilayers; Membranes; Physical Biochemistry; Protein Folding; Proteins

Garen, Alan

Research Interests:Development; Genetics; Medical Sciences; Molecular Biology

Gerstein, Mark

Research Interests:Biochemistry; Bioinformatics; Biophysics; Computational Biology; DNA; Genomics; Molecular Simulation; Proteins; Sequence Alignment; Structural Biology

Grindley, Nigel

Research Interests:Serine recombinases; site specific recombination; mechanisms of protein-DNA transactions; DNA polymerases

Hochstrasser, Mark

Research Interests:Adenosinetriphosphatase; Cell Growth Regulation; Chemical Cleavage; Chemical Conjugate; Chimeric Protein; Enzyme Activity; Enzyme Complex; Enzyme Mechanism; Enzyme Structure; Fungal Genetics; Gene Deletion Mutation; Immunoelectron Microscopy; Isozyme; Mass Spectrometry; Mutant; Proteasome; Protein Degradation; Protein Purification; Proteinase; Protooncogene; Saccharomyces Cerevisiae; Transcription Factor; Ubiquitin

Joyce, Catherine

Research Interests:DNA polymerase pathway; Dbh polymerase

Koelle, Michael

Research Interests:C. Elegans; G Protein; Neurotransmission; RGS Protein; Serotonin; Molecular Genetics; Neurobiology; Neurotransmitters; Proteins and Macromolecules; Receptors

Koleske, Anthony

Research Interests:Neuronal morphogenesis and degeneration; stress; schizophrenia; cell migration; cancer; metastasis; adhesion receptors

Konigsberg, William

Research Interests:Blood Coagulation; DNA Replication; Genetics; Proteins and Macromolecules

Lengyel, Peter

Research Interests:p200 family proteins; mammalian differentiation; cell proliferation; interferons

Miller, I George, Jr

Research Interests:Epstein-Barr Virus (EBV); Kaposi's Sarcoma-Associated Herpesvirus (KSHV); Tumor virology

Clinical Interests:Viral diseases; Hodgkin's Disease; Kaposi's Sarcoma; Lymphoma; Multiple Myeloma

Miranker, Andrew

Research Interests:Conformational changes in proteins which give rise to a special class of protein complex known as amyloid fibrils

Modis, Yorgo

Research Interests:Bacterial Infections; Biochemistry; Biophysics; Disease Resistance; Immune System; Immune System Disorders; Immunology; Infectious Diseases or Agents; Inflammatory Bowel Disease; Natural Processes Health Safety Medical; Pathogenesis; Receptors; Structural Biology; Structure or Function (Health or Safety or Medical); Vaccine

Moore, Peter

Research Interests:RNA Structures

Pollard, Thomas

Research Interests:Cytokinesis; cellular motility; role of actin filaments and myosin motors

Regan, Lynne

Research Interests:Mental retardation; protein-protein interactions; Fragile X Mental Retardation Protein (FMRP); protein-based nanomaterials

Rhoades, Elizabeth

Research Interests:Protein-Protein Interactions; Disordered Proteins; Protein Aggregation; Protein Folding; Fluorescence Spectroscopy

Schlieker, Christian

Research Interests:Alternative nuclear transport (nuclear egress), Protein quality control and its relation to viral pathogenesis, DYT1 Dystonia

Shulman, Robert

Research Interests:Nuclear magnetic resonance (NMR); metabolic pathways in vivo

Simon, Matthew

Research Interests:Chemical biology; Large non-coding RNAs; Epigenetic regulation; Histone modifications

Snyder, Michael

Research Interests:cell division; cell morphogenesis; sex specific gene expression; human genome characterization

Soll, Dieter

Research Interests:Aminoacyl-tRNA Synthesis; Functional Genomics; Life Science Biological; Mechanism of Translation

Solomon, Mark

Research Interests:Cell cycle; Ubiquitin-mediated proteolysis; Anaphase-promoting Complex

Steitz, Joan

Research Interests:Autoantibodies; Gene Expression; RNA; RNA Processing; SnRNPs; Viral Transformation

Steitz, Thomas

Research Interests:Protein Structure; Proteins and Macromolecules; Protein Nucleic Acid Complexes; X-ray Crystallography

Strobel, Scott

Research Interests:Antibiotics; Nucleic Acid Bioorganic Chemistry; Ribosome; Ribozyme; RNA Catalysis; RNA-Protein Interaction; Translation; Riboswitches, Biofuels; Endophytes; Natural Product Discovery

Summers, William

Research Interests:History of molecular biology; Development of target theory; History of Manchurian Plague, 1910-1911

Sung, Patrick

Research Interests:Repair of DNA double-strand breaks; repair by homologous recombination; repair by DNA end-joining

Wang, Hongwei

Research Interests:Cryo-electron microscopy; cytoskeleton dynamics; RNA quality control; RNA interference

Williams, Kenneth

Research Interests:protein profiling; phosphoproteomics; protein posttranslational modification

Wolin, Sandra

Research Interests:noncoding RNAs; RNA surveillance, RNA damage; autoimmune disease; environmental stress

Xiong, Yong

Research Interests:Innate immune systems; HIV; fatty acid synthase (FAS); polyketide synthase (PKS); Viral vectors