Molecular Biophysics and Biochemistry Faculty

Koelle, Michael R

Director of Undergraduate Studies

Research Interests:C. Elegans; G Protein; Neurotransmission; RGS Protein; Serotonin; Molecular Genetics; Neurobiology; Neurotransmitters; Proteins and Macromolecules; Receptors

Baserga, Susan J

Director of Medical Studies

Research Interests:Ribosome biogenesis; RRNA processing; U3 RNP structure and function; RNA helicases; Polymerase I transcription and processing

Koleske, Anthony J

Director of Graduate Admissions

Research Interests:Neuronal morphogenesis and degeneration; Stress; Schizophrenia; Cell migration; Cancer; Metastasis; Adhesion receptors

Biederer, Thomas

Research Interests:Biochemistry of membrane proteins; Molecular and cellular neuroscience; Synapse formation

Brudvig, Gary W

Research Interests:photosystem II; EPR spectroscopy; metalloproteins; artificial photosynthesis

De La Cruz, Enrique M.

Research Interests:Cytoskeleton; RNA helicases; Kinetics; Thermodynamics; Polymer Mechanics; Processivity

DiMaio, Daniel C.

Research Interests:Molecular Biology of Tumor Viruses; Mechanisms of Viral Carcinogenesis; Molecular Basis of Cell Growth Regulation and Senescence; Manipulating Cells and Viruses with Artificial Transmembrane Proteins; Oncogenes; Senescence; Signal Transduction; Trans-membrane Proteins; Tumor Suppressor Genes; Virology; Virus

Engelman, Donald Max

Research Interests:Helix Interactions; Lipid Bilayers; Membranes; Physical Biochemistry; Protein Folding; Proteins

Garen, Alan

Research Interests:Development; Genetics; Medical Sciences; Molecular Biology

Gerstein, Mark B

Research Interests:Biochemistry; Bioinformatics; Biophysics; Computational Biology; DNA; Genomics; Molecular Simulation; Proteins; Sequence Alignment; Structural Biology

Grindley, Nigel D. F.

Research Interests:Serine recombinases; site specific recombination; mechanisms of protein-DNA transactions; DNA polymerases

Hochstrasser, Mark W

Research Interests:Adenosinetriphosphatase; Cell Growth Regulation; Chemical Cleavage; Chemical Conjugate; Chimeric Protein; Enzyme Activity; Enzyme Complex; Enzyme Mechanism; Enzyme Structure; Fungal Genetics; Gene Deletion Mutation; Immunoelectron Microscopy; Isozyme; Mass Spectrometry; Mutant; Proteasome; Protein Degradation; Protein Purification; Proteinase; Protooncogene; Saccharomyces Cerevisiae; Transcription Factor; Ubiquitin

Joyce, Catherine M

Research Interests:DNA polymerase pathway; Dbh polymerase

Konigsberg, William H

Research Interests:Blood Coagulation; DNA Replication; Genetics; Proteins and Macromolecules

Lengyel, Peter

Research Interests:p200 family proteins; mammalian differentiation; cell proliferation; interferons

Miller, I George, Jr

Research Interests:Epstein-Barr Virus (EBV); Kaposi's Sarcoma-Associated Herpesvirus (KSHV); Tumor virology

Clinical Interests:Viral diseases; Hodgkin's Disease; Kaposi's Sarcoma; Lymphoma; Multiple Myeloma

Miranker, Andrew D

Research Interests:Conformational changes in proteins which give rise to a special class of protein complex known as amyloid fibrils

Moore, Peter B

Research Interests:RNA Structures

Pollard, Thomas Dean

Research Interests:Cytokinesis; cellular motility; role of actin filaments and myosin motors

Regan, Lynne J

Research Interests:Mental retardation; Protein-protein interactions; Fragile X Mental Retardation Protein (FMRP); Protein-based nanomaterials

Rhoades, Elizabeth

Research Interests:Protein-Protein Interactions; Disordered Proteins; Protein Aggregation; Protein Folding; Fluorescence Spectroscopy

Schlieker, Christian

Research Interests:DYT1 Dystonia, Membrane dynamics; Torsin ATPases; Alternative nuclear transport (nuclear egress); Protein quality control; viral pathogenesis

Shulman, Robert G

Research Interests:Nuclear magnetic resonance (NMR); metabolic pathways in vivo

Simon, Matthew

Research Interests:Chemical biology; Large non-coding RNAs; Epigenetic regulation; Histone modifications

Soll, Dieter G

Research Interests:Aminoacyl-tRNA Synthesis; Functional Genomics; Life Science Biological; Mechanism of Translation

Solomon, Mark J

Research Interests:Cell cycle; Ubiquitin-mediated proteolysis; Anaphase-promoting Complex

Steitz, Joan A

Research Interests:Autoantibodies; Gene Expression; RNA; RNA Processing; SnRNPs; Viral Transformation

Steitz, Thomas A

Research Interests:Protein Structure; Proteins and Macromolecules; Protein Nucleic Acid Complexes; X-ray Crystallography

Strobel, Scott A

Research Interests:Antibiotics; Nucleic Acid Bioorganic Chemistry; Ribosome; Ribozyme; RNA Catalysis; RNA-Protein Interaction; Translation; Riboswitches, Biofuels; Endophytes; Natural Product Discovery

Summers, William C

Research Interests:History of molecular biology; Development of target theory; History of Manchurian Plague, 1910-1911

Sung, Patrick

Research Interests:Repair of DNA double-strand breaks; Repair by homologous recombination; Repair by DNA end-joining

Wang, Hongwei

Research Interests:Cryo-electron microscopy; Cytoskeleton dynamics; RNA quality control; RNA interference

Williams, Kenneth R

Research Interests:protein profiling; phosphoproteomics; protein posttranslational modification

Wolin, Sandra L

Research Interests:Noncoding RNAs; RNA surveillance; RNA damage; Autoimmune disease; Environmental stress

Xiong, Yong

Research Interests:Innate immune systems; HIV; fatty acid synthase (FAS); polyketide synthase (PKS); Viral vectors