Matthew Simon

Assistant Professor of Molecular Biophysics and Biochemistry; Assistant Professor of Molecular Biophysics and Biochemistry (starting next year)

Research Interests

Chemical biology; Large non-coding RNAs; Epigenetic regulation; Histone modifications

Research Summary

My laboratory develops chemical and molecular approaches to study chromatin biology, with a focus on large non-coding RNAs.

Selected Publications

  • Simon, M.D., Chu, F., Racki, L.R., de la Cruz, C.C., Burlingame, A.L., Panning, B., Narlikar, G.J., and Shokat, K.M. The site-specific installation of methyl-lysine analogs into recombinant histones. Cell, 2007, 128, 1003-1012.
  • Simon, M.D., Wang C.I., Kharchenko, P., West, J.A., Chapman, B.A., Alekseyenko, A.A., Borowsky, M.L., Kuroda, M.I., Kingston, R.E. The Genomic Binding-Sites of a Non- Coding RNA. Proc Natl Acad Sci, 2011, 108, 20497-20502.

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