Mark B Gerstein, PhD

Albert L Williams Professor of Biomedical Informatics and Professor of Molecular Biophysics & Biochemistry, and of Computer Science. Co-Director of the Yale Program in Computational Biology & Bioinformatics

Departments & Organizations

Molecular Biophysics and Biochemistry: Genomics, Genetics, and Bioinformatics

Cancer Center, Yale: Genomics, Genetics, and Epigenetics

Center for RNA Science and Medicine, Yale

Keck: High Performance Computation | NHLBI Proteomics | NIDA Neuroproteomics Center

Office of Student Research

Program in Neurodevelopment and Regeneration

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Biochemistry, Biophysics and Structural Biology: DNA Dynamics; Protein Folding, Dynamics and Degradation | Computational Biology and Bioinformatics: Computational Analysis of Macromolecular Structures; Computational Approaches to Functional and Integrative Genomics; Heterogeneous Database Design and Information Integration; Theoretical Molecular Biology and Computational Algorithms | Molecular Cell Biology, Genetics and Development: Genetics and Genomics

Office of Cooperative Research


After graduating from Harvard summa cum laude with a A.B. in physics in 1989, Prof. Mark Gerstein earned a doctorate in theoretical chemistry and biophysics from Cambridge University in 1993. He did postdoctoral research in bioinformatics at Stanford University from 1993 to 1996. He came to Yale in 1997 as an assistant professor in the Department of Molecular Biophysics and Biochemistry, and since 1999, in the Computer Science Department. He was named an associate professor in 2001, and the following year became co-director of the Yale Computational Biology and Bioinformatics Program. Gerstein has published appreciably in the scientific literature, with >400 publications in total, including a number of them in prominent venues, such as Science, Nature, and Scientific American. His research is focused on bioinformatics, and he is particularly interested in data science & data mining, macromolecular geometry & simulation, and human genome annotation & cancer genomics.

Education & Training

PhD Cambridge University (1992)
Postdoctoral Fellow Stanford University

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