Lingeng Lu MD, PhD
Associate Research Scientist in Epidemiology (Chronic Diseases)
Research Interests
Cancer Etiology; Cancer Diagnostic and Prognostic Markers; Personalized Therapy
Current Projects
1. Non-coding RNA in cancer risk and progression
2. DNA methylation in cancer risk and progression
3. Genome-wide association study on endometrial cancer
4. Case-control studies of endometrial and pancreatic cancer etiologic factors
Selected Publications
- Lu L, Katsaros D, Wiley A, Rigault de la Longrais IA, Puopolo M, Schwartz P, Yu H. 2006. Promoter-specific transcripts of Insulin-like growth factor II in epithelial ovarian cancer. Gynecol Oncol 103:990-995.
- Lu L, Katsaros D, Wiley A, Rigault de la Longrais IA, Risch HA, Puopolo M, Yu H. 2006. “The relationship of insulin-like growth factor-II, insulin-like growth factor binding protein-3 and estrogen receptor-alpha expression to disease progression in epithelial ovarian cancer. Clin Cancer Res 12:1208-1204
- Lu L, Katsaros D, de la Longrais IA, Sochirca O, Yu H. 2007. Hypermethylation of let-7a-3 in epithelial ovarian cancer is associated with low insulin-like growth gactor II and good prognosis. Cancer Res 67: 10117-22
- Lu L, Katsaros D, Wiley A, de la Longrais IA, Puopolo M, Yu H. 2008. Klotho expression in epithelial ovarian cancer and its association with insulin-like growth factors and disease progression. Cancer Invest 26:185-192
- Qian B, Katsaros D, Lu L, Preti M, Durando A, Arisio R, Mu L, Yu H. 2009. High miR-21 expression in breast associated with poor disease-free survival in patients with early stage disease and high TGF-?1. Breast Cancer Res Treat 117:131-40
- Lu L, Katsaros D, Khvaramze S, Qian B, Wu Y, de la Longrais IA, Preti M, Menato G, Yu H. 2009. Pluripotent factor lin-28 and its homologue lin-28B in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II. Eur J Cancer 45:2212-8
- Risch H, Yu H, Lu L, Kidd M. 2010. ABO blood group and the association between Helicobacter pylori seropositivity and risk of pancreas cancer. J Natl Cancer Inst 102:502-5
- Ratner E, Lu L, Boeke M, Barnett R, Nallur S, Chin L, Pelletier C, Blitzblau R, Tassi R, Paranape T, Hui P, Godwin A, Yu H, Risch H, Rutherford T, Schwartz P, Santin A, Matloff E, Zelterman D, Slack F, Weidhaas J. 2010. A Kras-variant in ovarian cancer acts as genetic marker of cancer risk. Cancer Res Jul 20
- Tan H, Wang Q, Wang A, Ye Y, Feng N, Feng X, Lu L, Zheng Y, Xia Z. 2010. Influence of GSTs, CYP2E1 and mEH polymorphisms on 1, 3-butadiene-induced micronucleus frequency in Chinese workers. Toxicol Appl Pharmocol Jul 14
- Lu L, Katsaros D, Zhu Y, Hoffman A, Luca S, Marion CE, Mu L, Risch H, Yu H. 2010. Let-7a regulation of insulin-like growth factors in breast cancer. Breast cancer Res Treat Sep 17.
