Lesley Devine PhD

Associate Research Scientist in Laboratory Medicine; Scientific Director, Cancer Center Immune Monitoring Laboratory

Departments & Organizations

Laboratory Medicine: Immune Monitoring Core Facility


Research Interests

Effects of novel immune therapies on the immune system  more...


Education

  • BS, University of Strathclyde, 1991
  • Ph.D., University College, London, 1995

Selected Publications

  • Differential expression of the human CD8beta splice variants and regulation of the M-2 isoform by ubiquitination. Thakral D, Dobbins J, Devine L, Kavathas PB. J Immunol. 2008 Jun 1;180(11):7431-42.
  • Mapping the binding site on CD8 beta for MHC class I reveals mutants with enhanced binding. Devine L, Thakral D, Nag S, Dobbins J, Hodsdon ME, Kavathas PB. J Immunol. 2006 Sep 15;177(6):3930-8.
  • Location of the epitope for an anti-CD8alpha antibody 53.6.7 which enhances CD8alpha-MHC class I interaction indicates antibody stabilization of a higher affinity CD8 conformation. Devine L, Hodsdon ME, Daniels MA, Jameson SC, Kavathas PB. Immunol Lett. 2004 May 15;93(2-3):123-30.

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